Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Effect of Coating Type on Mechanical Properties and Controlled Drug Release of Pcl/Zein Coated 45S5 Bioactive Glass Scaffolds for Bone Tissue Engineering Publisher Pubmed



Fereshteh Z1, 2, 3 ; Nooeaid P1 ; Fathi M3, 4 ; Bagri A5 ; Boccaccini AR1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Institute of Biomaterials, Department of Materials Science and Engineering, University of Erlangen-Nuremberg, Cauerstrasse 6, Erlangen, 91058, Germany
  2. 2. Institute of Science, High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, 76315117, Iran
  3. 3. Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan, 8415683111, Iran
  4. 4. Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, 02139, MA, United States

Source: Materials Science and Engineering C Published:2015


Abstract

A highly investigated branch of tissue engineering involves the implantation of a highly porous biomaterial scaffold populated with appropriate cells to provide a three-dimensional (3D) environment in which new tissue can grow. As a drawback, the mechanical properties of foam-like BG-based scaffolds are in general poor in terms of strength and toughness for bone tissue engineering applications. Polymer coatings have been proposed to toughen brittle scaffolds, which can be achieved by the formation of a surface coating and by impregnation of microcracks and surface pores with a suitable polymer. The Fourier transform infrared (FTIR) spectra of different scaffolds were recorded on a Nicolet 6700 FTIR spectrometer in transmittance mode in the mid infrared region. Amounts of the released drugs at specified time periods were plotted as percentage of drug released versus time. The drug release evaluation was performed using 5 samples for each time up to 14 days and obtained results were expressed as the mean values and standard deviations.
Related Docs
View other Related Docs
1. Preparation and Characterization of Aligned Porous Pcl/Zein Scaffolds As Drug Delivery Systems Via Improved Unidirectional Freeze-Drying Method, Materials Science and Engineering C (2016)
2. Mechanical Properties and Drug Release Behavior of Pcl/Zein Coated 45S5 Bioactive Glass Scaffolds for Bone Tissue Engineering Application, Data in Brief (2015)
3. Evaluation of Physical, Mechanical and Biological Properties of Bioglass/Titania Scaffold Coated With Poly (3-Hydroxybutyrate)-Chitosan for Bone Tissue Engineering Applications, Materials Technology (2020)
4. Physical, Mechanical and Biological Performance of Phb-Chitosan/Mwcnts Nanocomposite Coating Deposited on Bioglass Based Scaffold: Potential Application in Bone Tissue Engineering, International Journal of Biological Macromolecules (2020)
5. Evaluation of the Effects of Zein Incorporation on Physical, Mechanical, and Biological Properties of Polyhydroxybutyrate Electrospun Scaffold for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2023)
6. Synthesis and Characterization of Bioactive Glass Coated Forsterite Scaffold for Tissue Engineering Applications, Journal of Alloys and Compounds (2017)
7. Development of Porous Photopolymer Resin-Swcnt Produced by Digital Light Processing Technology Using for Bone Femur Application, Archives of Bone and Joint Surgery (2021)
8. Evaluation of the Effects of Nano-Tio2 on Bioactivity and Mechanical Properties of Nano Bioglass-P3hb Composite Scaffold for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2016)
Experts (# of related papers)
View all Related Experts
Saeed Karbasi (52)
Mohammad Rafienia (40)
Other Related Docs
9. Evaluation of Physical and Mechanical Properties of Fi-Tri-Calcium Phosphate/Poly-3-Hydroxybutyrate Nanocomposite Scaffold for Bone Tissue Engineering Application, Scientia Iranica (2017)
10. Evaluation of Mechanical Property and Bioactivity of Nano-Bioglass 45S5 Scaffold Coated With Poly-3-Hydroxybutyrate, Journal of Materials Science: Materials in Medicine (2015)
11. Osteoconductive Visible Light-Crosslinkable Nanocomposite for Hard Tissue Engineering, Colloids and Surfaces A: Physicochemical and Engineering Aspects (2022)
12. In Vitro Study of the Recruitment and Expansion of Mesenchymal Stem Cells at the Interface of a Cu-Doped Pcl-Bioglass Scaffold, Biomimetics (2022)
13. In Vitro Bioactivity of Baghdadite-Coated Pcl –Graphene Nanocomposite Scaffolds: Mechanism of Baghdadite and Apatite Formation, Materials Technology (2020)
14. Evaluation of Physical, Mechanical and Biological Properties of Β-Tri-Calcium Phosphate/Poly-3-Hydroxybutyrate Nano Composite Scaffold for Bone Tissue Engineering Application, Materials Technology (2021)
15. Effects of Bioglass Nanoparticles on Bioactivity and Mechanical Property of Poly(3-Hydroxybutirate) Scaffolds, Scientia Iranica (2013)
16. The Journey of Multifunctional Bone Scaffolds Fabricated From Traditional Toward Modern Techniques, Bio-Design and Manufacturing (2020)
17. A Novel Nano-Composite Scaold for Cartilage Tissue Engineering, Scientia Iranica (2018)
18. A Ternary Nanocomposite Fibrous Scaffold Composed of Poly(Ε-Caprolactone)/Gelatin/Gehlenite (Ca2al2sio7): Physical, Chemical, and Biological Properties in Vitro, Polymers for Advanced Technologies (2021)
19. Physical, Mechanical, and Biological Performance of Chitosan-Based Nanocomposite Coating Deposited on the Polycaprolactone-Based 3D Printed Scaffold: Potential Application in Bone Tissue Engineering, International Journal of Biological Macromolecules (2023)
20. Synergetic Effect of Bioglass and Nano Montmorillonite on 3D Printed Nanocomposite of Polycaprolactone/Gelatin in the Fabrication of Bone Scaffolds, International Journal of Biological Macromolecules (2024)
21. Review of Recent Advances in Bone Scaffold Fabrication Methods for Tissue Engineering for Treating Bone Diseases and Sport Injuries, Tissue and Cell (2024)
22. The Electrospun Poly(Ε-Caprolactone)/Fluoridated Hydroxyapatite Nanocomposite for Bone Tissue Engineering, Polymers for Advanced Technologies (2020)
23. Scaffold Percolative Efficiency: In Vitro Evaluation of the Structural Criterion for Electrospun Mats, Journal of Materials Science: Materials in Medicine (2010)
24. Plant Protein-Based Nanoparticles and Their Biomedical Applications, Nanomaterials and Plant Potential (2019)
25. Fabrication of 3D Porous Polyurethane-Graphene Oxide Scaffolds by a Sequential Two-Step Processing for Non-Load Bearing Bone Defects, Physica Scripta (2024)
26. A Femoral Shape Porous Scaffold Bio-Nanocomposite Fabricated Using 3D Printing and Freeze-Drying Technique for Orthopedic Application, Materials Chemistry and Physics (2022)
27. Pcl/Agarose 3D-Printed Scaffold for Tissue Engineering Applications: Fabrication, Characterization, and Cellular Activities, Research in Pharmaceutical Sciences (2023)
28. Electrospun Captopril-Loaded Pcl-Carbon Quantum Dots Nanocomposite Scaffold: Fabrication, Characterization, and in Vitro Studies, Polymers for Advanced Technologies (2020)
29. Fabrication and Characterization of 3D Nanostructured Polycaprolactone-Gelatin/Nanohydroxyapatite-Nanoclay Scaffolds for Bone Tissue Regeneration, Journal of Polymers and the Environment (2024)
30. Physical and Mechanical Properties of a Poly-3-Hydroxybutyratecoated Nanocrystalline Hydroxyapatite Scaffold for Bone Tissue Engineering, Journal of Porous Materials (2012)
31. Preparation of a Novel Biodegradable Nanocomposite Scaffold Based on Poly (3-Hydroxybutyrate)/Bioglass Nanoparticles for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2010)
32. A Novel Flexible, Conductive, and Three-Dimensional Reduced Graphene Oxide/Polyurethane Scaffold for Cell Attachment and Bone Regeneration, Materials and Design (2022)
33. A Modular Approach to 3D-Printed Bilayer Composite Scaffolds for Osteochondral Tissue Engineering, Journal of Materials Science: Materials in Medicine (2024)
34. Tunable Cellular Interactions and Physical Properties of Nanofibrous Pcl-Forsterite: Gelatin Scaffold Through Sequential Electrospinning, Composites Science and Technology (2013)
35. Fabrication and Characterization of 3D-Printed Composite Scaffolds of Coral-Derived Hydroxyapatite Nanoparticles/Polycaprolactone/Gelatin Carrying Doxorubicin for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2024)
36. Preparation and Characterization of Poly Ε-Caprolactone-Gelatin/Multi-Walled Carbon Nanotubes Electrospun Scaffolds for Cartilage Tissue Engineering Applications, International Journal of Polymeric Materials and Polymeric Biomaterials (2020)
37. Preparation of Fibrin/Poly Vinyl Alcohol Electrospun Nanofibers Scaffold for Tissue Engineering Applications, Journal of Isfahan Medical School (2016)
38. 3D Printed Polylactic Acid-Based Nanocomposite Scaffold Stuffed With Microporous Simvastatin-Loaded Polyelectrolyte for Craniofacial Reconstruction, International Journal of Biological Macromolecules (2024)
39. Blood Compatibility and Cell Response Improvement of Poly Glycerol Sebacate/Poly Lactic Acid Scaffold for Vascular Graft Applications, Journal of Biomedical Materials Research - Part A (2021)
40. Fabrication of Elastin Additive on Polymethyl Methacrylate and Hydroxyapatite-Based Bioactive Bone Cement, Materials Chemistry and Physics (2022)
41. Cytocompatibility and Antibacterial Properties of Coaxial Electrospun Nanofibers Containing Ciprofloxacin and Indomethacin Drugs, Polymers (2022)
42. Synthetic Electrospun Nanofibers As a Supportive Matrix in Osteogenic Differentiation of Induced Pluripotent Stem Cells, Journal of Biomaterials Science, Polymer Edition (2022)
43. Polycaprolactone/Gelatin/Hydroxyapatite Nanocomposite Scaffold Seeded With Stem Cells From Human Exfoliated Deciduous Teeth to Enhance Bone Repair: In Vitro and in Vivo Studies, Materials Technology (2022)
44. Controlled Gentamicin- Strontium Release As a Dual Action Bone Agent: Combination of the Porous Titanium Scaffold and Biodegradable Polymers, Journal of Alloys and Compounds (2017)
45. Preparation and Characterization of 3D Nanocomposite Scaffold From Bioactive Glass/Β-Tricalcium Phosphate Via Robocasting Method for Bone Tissue Engineering, Journal of Non-Crystalline Solids (2022)
46. Investigation of the Mechanical Properties of a Bony Scaffold for Comminuted Distal Radial Fractures: Addition of Akermanite Nanoparticles and Using a Freeze-Drying Technique, Journal of the Mechanical Behavior of Biomedical Materials (2021)
47. Chondrogenesis of Mesenchymal Stromal Cells on the 3D Printed Polycaprolactone/Fibrin/Decellular Cartilage Matrix Hybrid Scaffolds in the Presence of Piascledine, Journal of Biomaterials Science, Polymer Edition (2024)
48. Comparative Evaluation of Hydroxyapatite and Nano-Bioglass in Two Forms of Conventional Micro-And Nano-Particles in Repairing Bone Defects (An Animal Study), Indian Journal of Dental Research (2015)
49. Effect of Calcium Silicate Nanoparticle on Surface Feature of Calcium Phosphates Hybrid Bio-Nanocomposite Using for Bone Substitute Application, Powder Technology (2020)
50. In Vivo and in Vitro Evaluation of Poly (Lactide-Co-Glycolide)/Bioactive Glass Nanocomposite Coating, Advanced Materials Research (2014)