Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
A Review on Drug Delivery Systems Containing Polymer Nanocomposites for Breast Cancer Treatment Publisher



Mohammadpourharatbar A1 ; Zare Y1 ; Rhee KY2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Biomaterials and Tissue Engineering Research Group, Department of Interdisciplinary Technologies, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
  2. 2. Department of Mechanical Engineering (BK21 Four), College of Engineering, Kyung Hee University, Yongin, South Korea

Source: Polymer Reviews Published:2024


Abstract

Breast cancer (BC) is one of the most common malignant cancers among women and the second leading cause of cancer-related deaths. Conventional treatments for BC are effective; however, they have several drawbacks, such as poor bioavailability and substantial side effects. On the other hand, using drug delivery systems (DDSs) have numerous benefits, such as suitable cancer targeting, reduced side effects, and controlled drug release. In recent years, DDSs have become a hotspot for the delivery of anti-BC drugs. The purpose of this review is to explore the progress of recent research on anti-BC drugs and the applications of polymer nanocomposites (PNCs) as DDSs for the treatment of BC. Moreover, this review summarizes important advances in the synthesis, preparation, and application of PNCs, using various nanomaterials and polymers, as nanocarriers for the treatment of BC. The challenges and opportunities associated with future clinical applications of PNCs in the treatment of BC are discussed. © 2023 Taylor & Francis Group, LLC.
Related Docs
View other Related Docs
1. Graphene-Based Electrochemical Biosensors for Breast Cancer Detection, Biosensors (2023)
2. Graphene Oxide Nanoarchitectures in Cancer Therapy: Drug and Gene Delivery, Phototherapy, Immunotherapy, and Vaccine Development, Environmental Research (2023)
3. Electrochemical Biosensors Based on Polymer Nanocomposites for Detecting Breast Cancer: Recent Progress and Future Prospects, Advances in Colloid and Interface Science (2022)
4. Prospects and Challenges of Anticancer Agents’ Delivery Via Chitosan-Based Drug Carriers to Combat Breast Cancer: A Review, Carbohydrate Polymers (2021)
5. Chitosan/Agarose/Graphene Oxide Nanohydrogel As Drug Delivery System of 5-Fluorouracil in Breast Cancer Therapy, Journal of Drug Delivery Science and Technology (2023)
6. Simulation of Electrical Conductivity for Polymer Silver Nanowires Systems, Scientific Reports (2023)
7. Codelivery of Hydrophobic and Hydrophilic Drugs by Graphene-Decorated Magnetic Dendrimers, Langmuir (2018)
8. A Review on Non-Enzymatic Electrochemical Biosensors of Glucose Using Carbon Nanofiber Nanocomposites, Biosensors (2022)
Experts (# of related papers)
View all Related Experts
Mona Navaei-Nigjeh (5)
Fatemeh Atyabi (2)
Other Related Docs
9. Graphene Aerogel Nanoparticles for In-Situ Loading/Ph Sensitive Releasing Anticancer Drugs, Colloids and Surfaces B: Biointerfaces (2020)
10. Novel Carboxymethyl Cellulose-Halloysite-Polyethylene Glycol Nanocomposite for Improved 5-Fu Delivery, International Journal of Biological Macromolecules (2023)
11. Development of Highly Efficient Niosomal Systems for Co-Delivery of Drugs and Genes to Treat Breast Cancer in Vitro and in Vivo, Cancer Nanotechnology (2022)
12. Applications of Iron Oxide Nanoparticles Against Breast Cancer, Journal of Nanomaterials (2022)
13. Assessment of Synthesized Chitosan/Halloysite Nanocarrier Modified by Carbon Nanotube for Ph-Sensitive Delivery of Curcumin to Cancerous Media, International Journal of Biological Macromolecules (2023)
14. Microfluidic-Assisted Synthesis and Modeling of Stimuli-Responsive Monodispersed Chitosan Microgels for Drug Delivery Applications, Scientific Reports (2022)
15. Local Delivery of Chemotherapeutic Agent in Tissue Engineering Based on Gelatin/Graphene Hydrogel, Journal of Materials Research and Technology (2021)
16. Modeling of Electrical Conductivity for Polymer–Carbon Nanofiber Systems, Materials (2022)
17. Synergistic Effects of Doxorubicin Loaded Silk Fibroin Nanoparticles and Cu-Tio2 Nanoparticles for Local Chemo-Sonodynamic Therapy Against Breast Cancer, International Journal of Biological Macromolecules (2025)
18. Synthesis and Characterization of the First Generation of Polyamino-Ester Dendrimer-Grafted Magnetite Nanoparticles From 3-Aminopropyltriethoxysilane (Aptes) Via the Convergent Approach, Silicon (2018)
19. Metal Organic Frameworks (Mofs) As Advanced Functional Materials for Food Applications, ACS Food Science and Technology (2024)
20. Multifunctional Carbon-Based Nanoparticles: Theranostic Applications in Cancer Therapy and Diagnosis, ACS Applied Bio Materials (2023)
21. Orthodontic Adhesive Doped With Nano-Graphene Oxide: Physico-Mechanical and Antimicrobial Properties; [Ортодонтический Адгезив, Активированный Нано-Оксидом Графена: Физико-Механические И Антимикробные Свойства], Folia Medica (2021)
22. A Review of Dna Nanoparticles-Encapsulated Drug/Gene/Protein for Advanced Controlled Drug Release: Current Status and Future Perspective Over Emerging Therapy Approaches, International Journal of Biological Macromolecules (2024)
23. Predicting of Electrical Conductivity for Polymer-Mxene Nanocomposites, Journal of Materials Research and Technology (2024)
24. Prediction of Interphase Parameters for Nanocellulose Composites Using a Modified Halpin–Tsai Approach, Cellulose (2023)
25. Improving Curcumin Constraints With Ph-Responsive Chitosan Based Graphene Oxide/Montmorillonite Nanohybrid Modified Agarose in Breast Cancer Therapy, BioNanoScience (2024)
26. Micelle-Based Nanoparticles With Stimuli-Responsive Properties for Drug Delivery, Nanotechnology Reviews (2024)
27. A Ph-Sensitive Nanocarrier Based on Bsa-Stabilized Graphene-Chitosan Nanocomposite for Sustained and Prolonged Release of Anticancer Agents, Scientific Reports (2021)
28. A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications, International Journal of Polymeric Materials and Polymeric Biomaterials (2021)
29. Modeling of Electrical Conductivity for Graphene-Based Systems by Filler Morphology and Tunneling Length, Diamond and Related Materials (2023)
30. Microfluidic-Assisted Synthesis and Modelling of Monodispersed Magnetic Nanocomposites for Biomedical Applications, Nanotechnology Reviews (2020)
31. Co-Loading of Cisplatin and Methotrexate in Nanoparticle-Based Pcl-Peg System Enhances Lung Cancer Chemotherapy Effects, Journal of Cluster Science (2022)
32. The Smart Nanocarrier Containing Zein/Starch Co-Biopolymers Enhanced by Graphitic Carbon Nitride; Exploring Opportunities in Brain Cancer Treatment, International Journal of Biological Macromolecules (2024)
33. Recent Advances and Trends in Nanoparticles Based Photothermal and Photodynamic Therapy, Photodiagnosis and Photodynamic Therapy (2022)
34. Pegylation of Graphene/Iron Oxide Nanocomposite: Assessment of Release of Doxorubicin, Magnetically Targeted Drug Delivery and Photothermal Therapy, Applied Nanoscience (Switzerland) (2020)
35. Biosensing Applications of Polyaniline (Pani)-Based Nanocomposites: A Review, Polymer Reviews (2021)
36. Targeted Cancer Therapy Through Antibody Fragments-Decorated Nanomedicines, Journal of Controlled Release (2017)
37. Effect of Contact Resistance on the Electrical Conductivity of Polymer Graphene Nanocomposites to Optimize the Biosensors Detecting Breast Cancer Cells, Scientific Reports (2022)
38. Influences of Graphene Morphology and Contact Distance Between Nanosheets on the Effective Conductivity of Polymer Nanocomposites, Journal of Materials Research and Technology (2023)
39. Photothermal Therapy-Mediated Autophagy in Breast Cancer Treatment: Progress and Trends, Life Sciences (2022)
40. Revisiting Structure-Property Relationship of Ph-Responsive Polymers for Drug Delivery Applications, Journal of Controlled Release (2017)
41. Stimuli-Responsive Mesoporous Silica Nps As Non-Viral Dual Sirna/Chemotherapy Carriers for Triple Negative Breast Cancer, Molecular Therapy Nucleic Acids (2017)
42. Targeted Ph- and Redox-Responsive Aus/Micelles With Low Cmc for Highly Efficient Sonodynamic Therapy of Metastatic Breast Cancer, Biomaterials Advances (2024)
43. Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery, Smart internal stimulus-responsive nanocarriers for drug and gene delivery (2015)
44. A Model for Predicting Tensile Modulus of Polymer Nanocomposites Reinforced With Cellulose Nanocrystals, Cellulose (2023)
45. Effect of Contact Number Among Graphene Nanosheets on the Conductivities of Tunnels and Polymer Composites, Scientific Reports (2023)
46. Smart Stimuli-Responsive Implantable Drug Delivery Systems for Programmed and On-Demand Cancer Treatment: An Overview on the Emerging Materials, Chemical Engineering Journal (2022)
47. Synthesis and Characterization of Cellulose, Β-Cyclodextrin, Silk Fibroin-Based Hydrogel Containing Copper-Doped Cobalt Ferrite Nanospheres and Exploration of Its Biocompatibility, Journal of Nanostructure in Chemistry (2023)
48. Development of Kovacs Model for Electrical Conductivity of Carbon Nanofiber–Polymer Systems, Scientific Reports (2023)
49. The Potential Use of Bacteria and Their Derivatives As Delivery Systems for Nanoparticles in the Treatment of Cancer, Journal of Drug Targeting (2025)
50. Catalase-Gold Nanoaggregates Manipulate the Tumor Microenvironment and Enhance the Effect of Low-Dose Radiation Therapy by Reducing Hypoxia, Biomedicine and Pharmacotherapy (2023)