Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Encapsulation of Bioactives Within Electrosprayed Κ-Carrageenan Nanoparticles Publisher Pubmed



Fani N1 ; Enayati MH1 ; Rostamabadi H2 ; Falsafi SR3
Authors

Source: Carbohydrate Polymers Published:2022


Abstract

In this study, an electrospray synthesis approach was utilized in which a solution mixture of a sensitive bioactive agent, D-limonene (DL, R-(+)-Limonene), and a nature-inspired polymer, κ-carrageenan (κC) was applied to design DL-κC nanoparticles (NPs) in a one step process. The engineered DL-κC NPs displayed spherical morphology and the maximum encapsulation efficiency of NPs was about 97 % by altering the mass ratio of DL to κC. The developed DL-κC NPs showed a pH-dependent release manner in vitro. Both photostability and thermostability of DL were promoted by increasing the κC concentration, and >85 % of the original DL could be preserved following 120 min of UV-light exposure in the NPs with 0.5 % κC. The results demonstrated that electrosprayed κC NPs are promising candidates for the design of high-loading pH-sensitive NPs for encapsulation of highly sensitive bioactive agents. © 2022
Related Docs
View other Related Docs
1. Seed Gum-Based Delivery Systems and Their Application in Encapsulation of Bioactive Molecules, Critical Reviews in Food Science and Nutrition (2023)
2. Design and Formulation of Nano/Micro-Encapsulated Natural Bioactive Compounds for Food Applications, Application of Nano/Microencapsulated Ingredients in Food Products (2020)
3. Insights Into Whey Protein-Based Carriers for Targeted Delivery and Controlled Release of Bioactive Components, Food Hydrocolloids (2022)
Experts (# of related papers)
View all Related Experts
Hadis Rostamabadi (15)
Gholamreza Askari (2)
Other Related Docs
4. Protein-Polysaccharide Interactions for the Fabrication of Bioactive-Loaded Nanocarriers: Chemical Conjugates and Physical Complexes, Pharmacological Research (2022)
5. Recent Advances in Electrospun Protein Fibers/Nanofibers for the Food and Biomedical Applications, Advances in Colloid and Interface Science (2023)
6. Basil Seed Gum Promotes the Electrospinnability of Wpi for Co-Encapsulation of Zno Nanoparticles and Curcumin, Carbohydrate Polymers (2022)
7. A Robust Emulsion Gel Based on Κ-Carrageenan and Dialdehyde Starch for Stimuli-Responsive of Hydrophobic Bioactive Agents, International Journal of Biological Macromolecules (2025)
8. Lycopene Nanodelivery Systems; Recent Advances, Trends in Food Science and Technology (2022)
9. Recent Advances in Oral Delivery of Bioactive Molecules: Focus on Prebiotic Carbohydrates As Vehicle Matrices, Carbohydrate Polymers (2022)
10. Limonene Loaded Cyclodextrin Nanosponge: Preparation, Characterization, Antibacterial Activity and Controlled Release, Food Bioscience (2021)
11. The Role of Emulsification Strategy on the Electrospinning of Β-Carotene-Loaded Emulsions Stabilized by Gum Arabic and Whey Protein Isolate, Food Chemistry (2022)
12. Recent Advances in Food Applications of Phenolic-Loaded Micro/Nanodelivery Systems, Critical Reviews in Food Science and Nutrition (2023)
13. Possible Health Risks Associated With Nanostructures in Food, Safety and Regulatory Issues of Nanoencapsulated Food Ingredients (2021)
14. Nanoencapsulation of Essential Oils From Industrial Hemp (Cannabis Sativa L.) By-Products Into Alfalfa Protein Nanoparticles, Food Chemistry (2022)
15. Genetically Engineered Viral Vectors and Organic-Based Non-Viral Nanocarriers for Drug Delivery Applications, Advanced Healthcare Materials (2022)
16. Ovalbumin, an Outstanding Food Hydrocolloid: Applications, Technofunctional Attributes, and Nutritional Facts, a Systematic Review, Food Hydrocolloids (2023)
17. Biomedical Applications of Lignin-Based Nanoparticles, Nanoparticles and their Biomedical Applications (2020)
18. Introduction to Bioactive Compounds: Definition, Advantages, and Limitations, (2025)
19. Nanoparticle Applications: A Comparative Study of Combining Nanoparticles With Cold Atmospheric Plasma Versus Electroporation Techniques, Advances in Natural Sciences: Nanoscience and Nanotechnology (2025)
20. Thermosensitive Folic Acid-Targeted Poly (Ethylene-Co-Vinyl Alcohol) Hemisuccinate Polymeric Nanoparticles for Delivery of Epirubicin to Breast Cancer Cells, Iranian Polymer Journal (English Edition) (2016)