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Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Development of Car-Nk Cells Targeting Cscc-Specific Antigens for Precision Immunotherapy

Mohammad Ahmadvand

Mohammad Ahmadvand

Associate Professor of Laboratory Hematology and Blood Banking

Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center

Tehran University of Medical Sciences

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1. Allogeneic Cart Progress: Platforms, Current Progress and Limitations, Frontiers in Immunology (2025)

2. Dyskeratosis Congenita Future: Hematopoietic Stem Cell Transplantation or Gene Therapy?, Gene Reports (2025)

3. Engineered Exosomes: Advanced Nanocarriers for Targeted Therapy and Drug Delivery in Hematological Malignancies, Cancer Nanotechnology (2025)

4. Evaluating the Safety and Feasibility of Allogeneic Nk Cell Infusion in High-Risk Lymphoma Patients Post-Autologous Stem Cell Transplantation, Discover Oncology (2025)

5. Ex Vivo-Expanded and Activated Haploidentical Natural Killer Cells Infusion Before Autologous Stem Cell Transplantation in High-Risk Neuroblastoma: A Phase I/Ii Pilot Study, Cancer Immunology, Immunotherapy (2025)

6. Immunotherapy With Ex Vivo–Expanded Donor-Derived Nk Cells After Haploidentical Hsct in Pediatric Patients With Aml: A Phase I Pilot Study, Current Research in Translational Medicine (2025)

7. Plasma-Circulating Mir-638, Mir-6511B-5P, Mir-3613-5P, Mir-455-3P, Mir-5787, and Mir-548A-3P As Noninvasive Biomarkers of Immune Reconstitution Post-Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients, Transplant Immunology (2025)

8. Reduced Cish Expression by Sirna Knockdown in Natural Killer Cells Promotes Anti-Tumor Effects Against Gastric Cancer Cell Lines, Discover Oncology (2025)

9. Revolutionizing Cancer Treatment: Engineering Mesenchymal Stem Cell-Derived Small Extracellular Vesicles, Cancer Cell International (2025)

10. Snhg14 Lncrna As a Prognostic Biomarker in Adult Non-M3 Aml Patients, Hematology/oncology and stem cell therapy (2025)

11. Car-Nk Cells As Promising Immune Therapeutics: Platforms and Current Progress, International Journal of Cancer Management (2024)

12. Cell Therapy Using Anti-Nkg2a Pretreated Natural Killer Cells in Patients With Hepatocellular Carcinoma, Advanced Pharmaceutical Bulletin (2024)

13. Circulating Micrornas As the Achilles Forte of Diagnostics and Prognostics in Acute Graft Versus Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation, Gene Reports (2024)

14. Comprehensive Analysis of the Role of Ubiquitin-Specific Peptidases in Colorectal Cancer: A Systematic Review, World Journal of Gastrointestinal Oncology (2024)

15. Correction: Ubiquitin-Specific Proteases (Usps) in Leukemia: A Systematic Review (Bmc Cancer, (2024), 24, 1, (894), 10.1186/S12885-024-12614-X), BMC Cancer (2024)

16. Cytokine-Treated Natural Killer Cells Derived From Cord Blood Haematopoietic Stem Cells Exhibit Potential Cytotoxicity Against Cancer Cells, International Journal of Cancer Management (2024)

17. Diagnosis of Cutaneous Acute Graft‑Versus‑Host Disease Through Circulating Plasma Mir-638, Mir-6511B-5P, Mir-3613-5P, Mir-455-3P, Mir-5787, and Mir-548A-3P As Prospective Noninvasive Biomarkers Following Allogeneic Hematopoietic Stem Cell Transplantation, Clinical Transplantation (2024)

18. Efficacy and Safety of Adoptive T-Cell Therapy in Treating Cytomegalovirus Infections Post-Haematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis, Reviews in Medical Virology (2024)

19. Immune Checkpoints and Ncrnas: Pioneering Immunotherapy Approaches for Hematological Malignancies, Cancer Cell International (2024)

20. Immunologic Responses to the Third and Fourth Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Vaccines in Cell Therapy Recipients: A Systematic Review and Meta-Analysis, Virology Journal (2024)

21. The Effect of Circulating Exosomes Obtained From Young and Old Individuals on the Aging Related Htert and P16 Expression in Hematopoietic Stem Cells, Natural Products Journal (2024)

22. Ubiquitin-Specific Proteases (Usps) in Leukemia: A Systematic Review, BMC Cancer (2024)

23. Upregulation of Lnc-Foxd2-As1, Cdc45, and Cdk1 in Patients With Primary Non-M3 Aml Is Associated With a Worse Prognosis, Blood Research (2024)

24. Abnormal Promoter Methylation of Nucleotide-Binding Oligomerization Domain Containing 2 (Nod2) Gene in the Pathogenesis of Crohn’S Disease, Acta Medica Iranica (2023)

25. Cancer Immunotherapy Via Stem Cell-Derived Nk Cells, Immunotherapy (2023)

26. Chemo-Immune Cell Therapy by Intratumoral Injection of Adoptive Nk Cells With Capecitabine in Gastric Cancer Xenograft Model, BioImpacts (2023)

27. Evaluation of Safety and Immunogenicity of a Recombinant Receptor-Binding Domain (Rbd)-Tetanus Toxoid (Tt) Conjugated Sars-Cov-2 Vaccine (Pastocovac) in Recipients of Autologous Hematopoietic Stem Cell Transplantation Compared to the Healthy Controls; a Prospective, Open-Label Clinical Trial, Vaccines (2023)

28. High Expression of Long Noncoding Rna Norad Is Associated With Poor Clinical Outcomes in Non-M3 Acute Myeloid Leukemia Patients, Hematology/ Oncology and Stem Cell Therapy (2023)

29. Homologous Versus Heterologous Prime-Boost Covid-19 Vaccination in Autologous Hematopoietic Stem Cell Transplantation Recipients: A Blinded Randomized Controlled Trial, Frontiers in Immunology (2023)

30. Investigation of Kir/Hla Relationship and Other Clinical Variables After T-Cell-Replete Haploidentical Bone Marrow Transplantation in Patients With Acute Myeloid Leukemia (Aml), BMC Immunology (2023)

31. Investigation of Kir/Hla Relationship and Other Clinical Variables After T-Cell-Replete Haploidentical Bone Marrow Transplantation in Patients With Acute Myeloid Leukemia (Aml), BMC Immunology (2023)

32. Phase I Non-Randomized Clinical Trial of Allogeneic Natural Killer Cells Infusion in Acute Myeloid Leukemia Patients, BMC Cancer (2023)

33. Safety and Feasibility Study of Ex Vivo Expanded Allogeneic-Nk Cells Infusion in Patients With Acute Pneumonia Caused by Covid-19, Pilot and Feasibility Studies (2023)

34. The Influence of Kir Gene Polymorphisms and Kir-Ligand Binding on Outcomes in Hematologic Malignancies Following Haploidentical Stem Cell Transplantation: A Comprehensive Review, Current Cancer Drug Targets (2023)

35. The Influence of Kir Gene Polymorphisms and Kir-Ligand Binding on Outcomes in Hematologic Malignancies Following Haploidentical Stem Cell Transplantation: A Comprehensive Review, Current Cancer Drug Targets (2023)

36. The Role of Ubiquitin-Specific Peptidases in Colorectal Cancer: A Systematic Review Protocol, Asia Pacific Journal of Cancer Biology (2023)

37. Three Doses of a Recombinant Conjugated Sars-Cov-2 Vaccine Early After Allogeneic Hematopoietic Stem Cell Transplantation: Predicting Indicators of a High Serologic Response—A Prospective, Single-Arm Study, Frontiers in Immunology (2023)

38. A Comparative Study of the Bone Marrow and Umbilical Cord-Derived Mesenchymal Stem Cells (Mscs) Efficiency on Generating Msc-Educated Macrophages (Mems), Asian Pacific Journal of Cancer Prevention (2022)

39. Association of Aberrant Promoter Methylation Changes in the Suppressor of Cytokine Signaling 3 (Socs3) Gene With Susceptibility to Crohn's Disease, Avicenna Journal of Medical Biotechnology (2022)

40. Identification of Mir-195-5P As a Novel Prognostic Biomarker for Colorectal Cancer, Molecular Biology Reports (2022)

41. In Vitro Generation of Bk Polyomavirus-Specific T Cells for Adoptive Cell Therapy in Refractory Cystitis Hemorrhagic Patients After Hematopoietic Stem Cell Transplantation, BMC Immunology (2022)

42. The Long-Term Outcome and Efficacy of Pr1/Bcr-Abl Multipeptides Vaccination in Chronic Myeloid Leukemia: Results of a 7-Year Longitudinal Investigation, Iranian Journal of Blood and Cancer (2022)

43. Use of Expanded Carrier Screening for Retrospective Diagnosis of Two Deceased Siblings With Van Maldergem Syndrome 2: Case Report, Asian Biomedicine (2022)

44. Adaptive Nk Cell Therapy Modulated by Anti-Pd-1 Antibody in Gastric Cancer Model, Frontiers in Pharmacology (2021)

45. Circulating Mir-455-3P, Mir-5787, and Mir-548A-3P As Potential Noninvasive Biomarkers in the Diagnosis of Acute Graft-Versus-Host Disease: A Validation Study, Annals of Hematology (2021)

46. Fas-670A>G Gene Polymorphism and the Risk of Allograft Rejection After Organ Transplantation: A Systematic Review and Meta-Analysis, Blood Research (2021)

47. Influence of Follicular Fluid and Seminal Plasma on the Expression of Endometrial Receptivity Genes in Endometrial Cells, Cell Journal (2021)

48. Molecular Genetics of Cleidocranial Dysplasia, Fetal and Pediatric Pathology (2021)

49. Young Breast Cancer: Novel Gene Methylation in Wbc, Asian Pacific Journal of Cancer Prevention (2021)

50. Differential Micrornas Expression in Acute Graft-Versus-Host Disease As Potential Diagnostic Biomarkers, Bone Marrow Transplantation (2020)

51. Upregulated Mir-410 Is Linked to Poor Prognosis in Colorectal Cancer, British Journal of Biomedical Science (2020)

52. Association and in Silico Investigations of Mir-302C Insertion/Deletion Variant As a Novel Biomarker With Susceptibility to Gastric Cancer, Journal of Cellular Biochemistry (2019)

53. Clinical Significance of Cell-Free Dna As a Prognostic Biomarker in Patients With Diffuse Large B-Cell Lymphoma, Blood Research (2019)

54. Identification of Mir-125A As a Novel Plasma Diagnostic Biomarker for Chronic Lymphoblastic Leukemia, Clinical Laboratory (2019)

55. Micrornas As Potential Diagnostic, Prognostic, and Predictive Biomarkers for Acute Graft-Versus-Host Disease, Biology of Blood and Marrow Transplantation (2019)

56. A Novel 8-Bp Duplication in Adat3 Causes Mild Intellectual Disability, Human Genome Variation (2018)

57. Altered Expression of Malat 1 Lncrna in Chronic Lymphocytic Leukemia Patients, Correlation With Cytogenetic Findings, Blood Research (2018)

58. Expression Analysis of Pvt1, Ccdc26, and Ccat1 Long Noncoding Rnas in Acute Myeloid Leukemia Patients, Genetic Testing and Molecular Biomarkers (2018)

59. Low Expression of Long Noncoding Rna Irain Is Associated With Poor Prognosis in Non-M3 Acute Myeloid Leukemia Patients, Genetic Testing and Molecular Biomarkers (2018)

60. Over Expression of Circulating Mir-155 Predicts Prognosis in Diffuse Large B-Cell Lymphoma, Leukemia Research (2018)

61. Prognostic Value of Runx1 Mutations in Aml: A Meta-Analysis, Asian Pacific Journal of Cancer Prevention (2018)

62. Another Novel Missense Mutation in Arsb Gene in Iran, Acta Medica Iranica (2017)

63. Genetic, Hematologic and Psychological Aspects of Leukemia, Cancer Genetics and Psychotherapy (2017)

64. Kleefstra Syndrome: The First Case Report From Iran, Acta Medica Iranica (2017)

65. Methylomics of Breast Cancer: Seeking Epimarkers in Peripheral Blood of Young Subjects, Tumor Biology (2017)