Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Non-Viral Delivery Systems for Breast Cancer Gene Therapy
Mina Mirian
Mina Mirian

Associate Professor of Molecular Medicine

Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences

Isfahan University of Medical Sciences

Related Documents
1. In Vitro and in Vivo Evaluation of Novel Dtx-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes, Recent Patents on Anti-Cancer Drug Discovery (2020)
2. Boron Phenyl Alanine Targeted Ionic Liquid Decorated Chitosan Nanoparticles for Mitoxantrone Delivery to Glioma Cell Line, Pharmaceutical Development and Technology (2021)
3. Co-Delivery of Dasatinib and Mir-30A by Liposomes Targeting Neuropilin-1 Receptors for Triple-Negative Breast Cancer Therapy, Journal of Materials Chemistry B (2024)
4. Fabrication and Evaluation of a Dual-Targeting Nanoparticle Mediated Crispr/Cas9 Delivery to Combat Drug Resistance in Breast Cancer Cells, Journal of Drug Delivery Science and Technology (2023)
5. Synthesis and in Vitro Evaluation of Self-Assembling Biocompatible Heparin-Based Targeting Polymeric Micelles for Delivery of Doxorubicin to Leukemic Cells, Research in Pharmaceutical Sciences (2025)
6. Her-2 Aptamer-Targeted Ecoflex® Nanoparticles Loaded With Docetaxel Promote Breast Cancer Cells Apoptosis and Anti-Metastatic Effect, IET Nanobiotechnology (2019)
7. Hyaluronic Acid-Conjugated Gliadin Nanoparticles for Targeted Delivery of Usnic Acid in Breast Cancer: An in Vitro / in Vivo Translational Study, Journal of Drug Delivery Science and Technology (2023)
8. Comparing the Transfection Efficiency of Cationic Monomer Ratios in Vinylimidazole and Aminoethyl Methacrylate Copolymers, International Journal of Pharmaceutics: X (2025)
9. Co-Delivery of Interferon Regulatory Factor 5 (Irf5) Sirna and Dasatinib by a Disulfide Bond Bearing Polymeric Carrier for Enhanced Anti-Inflammatory Effects, International Journal of Biological Macromolecules (2024)
10. Bio-Membrane Selex As a New Approach for Selecting Ss-Dna Aptamers That Bind to the Hydatid Cyst Laminated Layer, Current Molecular Medicine (2023)
All Documents
1. Comparing the Transfection Efficiency of Cationic Monomer Ratios in Vinylimidazole and Aminoethyl Methacrylate Copolymers, International Journal of Pharmaceutics: X (2025)
2. Synthesis and in Vitro Evaluation of Self-Assembling Biocompatible Heparin-Based Targeting Polymeric Micelles for Delivery of Doxorubicin to Leukemic Cells, Research in Pharmaceutical Sciences (2025)
3. A Forsterite-Reinforced Polypropylene Fumarate/Methoxy Polyethylene Glycol-Hydrogel Enriched With Flavonoid Nanoparticles Enhances Osteoconductivity, Materials Advances (2024)
4. Biocompatible Nanocomposite Scaffolds Based on Carrageenan Incorporating Hydroxyapatite and Hesperidin Loaded Nanoparticles for Bone Tissue Regeneration, Polymers for Advanced Technologies (2024)
5. Co-Delivery of Dasatinib and Mir-30A by Liposomes Targeting Neuropilin-1 Receptors for Triple-Negative Breast Cancer Therapy, Journal of Materials Chemistry B (2024)
6. Co-Delivery of Interferon Regulatory Factor 5 (Irf5) Sirna and Dasatinib by a Disulfide Bond Bearing Polymeric Carrier for Enhanced Anti-Inflammatory Effects, International Journal of Biological Macromolecules (2024)
7. Hypoxia-Preconditioned Wj-Msc Spheroid-Derived Exosomes Delivering Mir-210 for Renal Cell Restoration in Hypoxia-Reoxygenation Injury, Stem Cell Research and Therapy (2024)
8. Intersecting Pathways: The Role of Hybrid E/M Cells and Circulating Tumor Cells in Cancer Metastasis and Drug Resistance, Drug Resistance Updates (2024)
9. Keratinocyte Exosomes for Topical Delivery of Tofacitinib in Treatment of Psoriasis: An in Vitro/ in Vivo Study in Animal Model of Psoriasis, Pharmaceutical Research (2024)
10. Microrna-219 in the Central Nervous System: A Potential Theranostic Approach, Research in Pharmaceutical Sciences (2024)
11. Pepgen-P15 Delivery to Bone: A Novel 3D Printed Scaffold for Enhanced Bone Regeneration, Journal of Drug Delivery Science and Technology (2024)
12. Spirulina Protein Concentrate Hydrogel Reinforced by Hydroxyapatite Nanoparticles and Hydroxychloroquin: A Novel Platform for Bone Regeneration, Materials Today Communications (2024)
13. Targeted Delivery of Liposomal Ribociclib to Slc7a5 Transporters in Breast Cancer Cells, Investigational New Drugs (2024)
14. Targeting Vimentin: A Multifaceted Approach to Combatting Cancer Metastasis and Drug Resistance, Cancer and Metastasis Reviews (2024)
15. Anderson-Type Manganese Polyoxomolybdate Hybrid Nanocomposite for Boosting Drug Delivery Against Breast Cancer, Journal of Drug Delivery Science and Technology (2023)
16. Anderson-Type Manganese Polyoxomolybdate Hybrid Nanocomposite for Boosting Drug Delivery Against Breast Cancer, Journal of Drug Delivery Science and Technology (2023)
17. Bio-Membrane Selex As a New Approach for Selecting Ss-Dna Aptamers That Bind to the Hydatid Cyst Laminated Layer, Current Molecular Medicine (2023)
18. Crispr Technology: A Versatile Tool to Model, Screen, and Reverse Drug Resistance in Cancer, European Journal of Cell Biology (2023)
19. Crosstalk of Transcriptional Regulators of Adaptive Immune System and Micrornas: An Insight Into Differentiation and Development, Cells (2023)
20. Exosomes As Efficient Platforms for Delivering Adenosine-Tetra Peptide Conjugate to Pancreatic Cancer Cells: An in Vitro/In Silico Study, Journal of Drug Delivery Science and Technology (2023)
21. Fabrication and Evaluation of a Dual-Targeting Nanoparticle Mediated Crispr/Cas9 Delivery to Combat Drug Resistance in Breast Cancer Cells, Journal of Drug Delivery Science and Technology (2023)
22. Gene Network Analysis of Oxaliplatin-Resistant Colorectal Cancer to Target a Crucial Gene Using Chitosan/Hyaluronic Acid/Protamine Polyplexes Containing Crispr-Cas9, Biochimica et Biophysica Acta - General Subjects (2023)
23. Hyaluronic Acid-Conjugated Gliadin Nanoparticles for Targeted Delivery of Usnic Acid in Breast Cancer: An in Vitro / in Vivo Translational Study, Journal of Drug Delivery Science and Technology (2023)
24. Investigation of Biological Effects of New Tetrazole Compounds on Cancer Cell Lines (Hela, Mcf-7) and Common Microorganisms (Staphylococcus Aureus, Escherichia Coli, Candida Albicans), Journal of Isfahan Medical School (2023)
25. Peptide-Based Pegylated Polyurethane Nanoparticles for Paclitaxel Delivery in Hela Cancer Cells: The Art of the Architecture Design in Nanocarriers, Polymer Bulletin (2023)
26. Smart Redox-Sensitive Micelles Based on Chitosan for Dasatinib Delivery in Suppressing Inflammatory Diseases, International Journal of Biological Macromolecules (2023)
27. The Circadian Rhythm: An Influential Soundtrack in the Diabetes Story, Frontiers in Endocrinology (2023)
28. Thermosensitive Tmpo-Oxidized Lignocellulose/Cationic Agarose Hydrogel Loaded With Deferasirox Nanoparticles for Photothermal Therapy in Melanoma, International Journal of Biological Macromolecules (2023)
29. Circadian and Immunity Cycle Talk in Cancer Destination: From Biological Aspects to in Silico Analysis, Cancers (2022)
30. Design, Synthesis, and Cytotoxicity Evaluation of Novel Indole-Acylhydrazone Derivatives of 4-Pyridinone As Potential Histone Deacetylase-2 Inhibitors, Research in Pharmaceutical Sciences (2022)
31. Evaluation of Thermosensitive Chitosan Hydrogel Containing Gefitinib Loaded Cellulose Acetate Butyrate Nanoparticles in a Subcutaneous Breast Cancer Model, International Journal of Pharmaceutics (2022)
32. Evolocumab, a Pcsk9 Inhibitor, Protects Human Endothelial Cells Against H2o2-Induced Oxidative Stress, Archives of Physiology and Biochemistry (2022)
33. Expression of Recombinant Insulin-Like Growth Factor-Binding Protein-3 Receptor in Mammalian Cell Line and Prokaryotic (Escherichia Coli) Expression Systems, Advanced Biomedical Research (2022)
34. Fabrication and Optimization of Electrospun Polymeric Nanofibers Loaded With 5-Fluorouracil and Rosemary Extract, Pharmaceutical Nanotechnology (2022)
35. Glutathione Targeted Tragacanthic Acid-Chitosan As a Non-Viral Vector for Brain Delivery of Mirna-219A-5P: An in Vitro/In Vivo Study, International Journal of Biological Macromolecules (2022)
36. Local Delivery of Usnic Acid Loaded Rhamnolipid Vesicles by Gelatin / Tragacanth Gum / Montmorillonite/ Vanillin Cryogel Scaffold for Expression of Osteogenic Biomarkers and Antimicrobial Activity, Journal of Drug Delivery Science and Technology (2022)
37. Myrsinane-Type Diterpenes From Euphorbia Gedrosiaca With Cell Growth Inhibitory Activity and Apoptotic Effects on Melanoma Cancer Cells, Fitoterapia (2022)
38. Ph-Responsive Glucosamine Anchored Polydopamine Coated Mesoporous Silica Nanoparticles for Delivery of Anderson-Type Polyoxomolybdate in Breast Cancer, Journal of Microencapsulation (2022)
39. Ph-Responsive Glucosamine Anchored Polydopamine Coated Mesoporous Silica Nanoparticles for Delivery of Anderson-Type Polyoxomolybdate in Breast Cancer, Journal of Microencapsulation (2022)
40. Redox Responsive Polymeric Micelles of Gellan Gum/Abietic Acid for Targeted Delivery of Ribociclib, International Journal of Biological Macromolecules (2022)
41. Thermo-Responsive Hydrogels Based on Methylcellulose/Persian Gum Loaded With Taxifolin Enhance Bone Regeneration: An in Vitro/In Vivo Study, Cellulose (2022)
42. 4-Hydroxyhalcone Effects on Cisplatin-Induced Genotoxicity Model, Toxicology Research (2021)
43. Boron Phenyl Alanine Targeted Chitosan–Pnipaam Core–Shell Thermo-Responsive Nanoparticles: Boosting Drug Delivery to Glioblastoma in Bnct, Drug Development and Industrial Pharmacy (2021)
44. Boron Phenyl Alanine Targeted Ionic Liquid Decorated Chitosan Nanoparticles for Mitoxantrone Delivery to Glioma Cell Line, Pharmaceutical Development and Technology (2021)
45. Co-Delivery of Rituximab Targeted Curcumin and Imatinib Nanostructured Lipid Carriers in Non-Hodgkin Lymphoma Cells, Journal of Liposome Research (2021)
46. Effect of Bassorin (Derived From Gum Tragacanth) and Halloysite Nanotubes on Physicochemical Properties and the Osteoconductivity of Methylcellulose-Based Injectable Hydrogels, International Journal of Biological Macromolecules (2021)
47. Fabrication and Characterization of Injectable Thermosensitive Hydrogel Containing Dipyridamole Loaded Polycaprolactone Nanoparticles for Bone Tissue Engineering, Journal of Drug Delivery Science and Technology (2021)
48. Generation of Hbsag Dna Aptamer Using Modified Cell-Based Selex Strategy, Molecular Biology Reports (2021)
49. Holothurin B Isolated From Holothuria Atra Inhibits Angiogenesis More Potent Than Curcumin in Vitro, Research Journal of Pharmacognosy (2021)
50. Pegylated Multifunctional Ph-Responsive Targeted Polymeric Micelles for Ovarian Cancer Therapy: Synthesis, Characterization and Pharmacokinetic Study, International Journal of Polymeric Materials and Polymeric Biomaterials (2021)
51. Simvastatin Nanosuspensions Prepared Using a Combination of Ph-Sensitive and Timed-Release Approaches for Potential Treatment of Colorectal Cancer, Pharmaceutical Development and Technology (2021)
52. The Molecular Basis of Covid-19 Pathogenesis, Conventional and Nanomedicine Therapy, International Journal of Molecular Sciences (2021)
53. Apamin Administration Impact on Mir-219 and Mir-155-3P Expression in Cuprizone Induced Multiple Sclerosis Model, Molecular Biology Reports (2020)
54. Covalent Triazine-Based Polyimine Framework As a Biocompatible Ph-Dependent Sustained-Release Nanocarrier for Sorafenib: An in Vitro Approach, Journal of Molecular Liquids (2020)
55. Development of a Rp-Hplc Method for Analysis of Docetaxel in Tumor-Bearing Mice Plasma and Tissues Following Injection of Docetaxel-Loaded Ph Responsive Targeting Polymeric Micelles, Research in Pharmaceutical Sciences (2020)
56. Encapsulation of Imatinib in Targeted Kit-5 Nanoparticles for Reducing Its Cardiotoxicity and Hepatotoxicity, Anti-Cancer Agents in Medicinal Chemistry (2020)
57. Hydroxychloroquine Effects on Mir-155-3P and Mir-219 Expression Changes in Animal Model of Multiple Sclerosis, Metabolic Brain Disease (2020)
58. In Vitro and in Vivo Evaluation of Novel Dtx-Loaded Multifunctional Heparin-Based Polymeric Micelles Targeting Folate Receptors and Endosomes, Recent Patents on Anti-Cancer Drug Discovery (2020)
59. Micrornas As the Actors in the Atherosclerosis Scenario, Journal of Physiology and Biochemistry (2020)
60. Micrornas As the Actors in the Atherosclerosis Scenario, Journal of Physiology and Biochemistry (2020)
61. Novel Ph-Triggered Biocompatible Polymeric Micelles Based on Heparin–Α-Tocopherol Conjugate for Intracellular Delivery of Docetaxel in Breast Cancer, Pharmaceutical Development and Technology (2020)
62. Preparation and Characterization of Dry Powder Containing Sunitinib Loaded Phbv Nanoparticles for Enhanced Pulmonary Delivery, Journal of Drug Delivery Science and Technology (2020)
63. Preparation and Evaluation of Inhalable Dry Powder Containing Glucosamine-Conjugated Gefitinib Slns for Lung Cancer Therapy, Drug Development and Industrial Pharmacy (2020)
64. Targeted Nanoparticles for Co-Delivery of 5-Fu and Nitroxoline, a Cathepsin B Inhibitor, in Hepg2 Cells of Hepatocellular Carcinoma, Anti-Cancer Agents in Medicinal Chemistry (2020)
65. The Effect of Pramlintide, an Antidiabetic Amylin Analogue, on Angiogenesis-Related Markers in Vitro, Research in Pharmaceutical Sciences (2020)
66. Development of Α4 Integrin Dna Aptamer As a Potential Therapeutic Tool for Multiple Sclerosis, Journal of Cellular Biochemistry (2019)
67. Development of Α4 Integrin Dna Aptamer As a Potential Therapeutic Tool for Multiple Sclerosis, Journal of Cellular Biochemistry (2019)
68. Her-2 Aptamer-Targeted Ecoflex® Nanoparticles Loaded With Docetaxel Promote Breast Cancer Cells Apoptosis and Anti-Metastatic Effect, IET Nanobiotechnology (2019)
69. Novel Palladium Complex: Cytotoxicity Against Cisplatin-Resistant K562 Cells, Iranian Journal of Pharmaceutical Research (2019)
70. Synthesis of Pectin-Deoxycholic Acid Conjugate for Targeted Delivery of Anticancer Drugs in Hepatocellular Carcinoma, International Journal of Biological Macromolecules (2019)
71. Construction and Characterization of Human Embryonic Kidney-(Hek)-293T Cell Overexpressing Truncated Α4 Integrin, Research in Pharmaceutical Sciences (2018)
72. Construction and Characterization of Human Embryonic Kidney-(Hek)-293T Cell Overexpressing Truncated Α4 Integrin, Research in Pharmaceutical Sciences (2018)
73. Disruption of Sox6 Gene Using Crispr/Cas9 Technology for Gamma-Globin Reactivation: An Approach Towards Gene Therapy of Β-Thalassemia, Journal of Cellular Biochemistry (2018)
74. Induction of Apoptosis in Toxoplasma Gondii Infected Hela Cells by Cisplatin and Sodium Azide and Isolation of Apoptotic Bodies and Potential Use for Vaccination Against Toxoplasma Gondii, Iranian Journal of Parasitology (2018)
75. Plga-Peg-Ra-Based Polymeric Micelles for Tumor Targeted Delivery of Irinotecan, Pharmaceutical Development and Technology (2018)
76. Using Enzyme-Linked Aptamer Assay to Detect Hepatitis B Surface Antigen in Comparison to Enzyme-Linked Immunosorbent Assay, Journal of Isfahan Medical School (2018)
77. Evaluation of Cytotoxic Effects of a Dinuclearpalladacycle Derivative, Biphosphinic Complex, on Cisplatin-Resistant Ht-29 Cells, Journal of Reports in Pharmaceutical Sciences (2017)
78. Oligonucleotide Aptamers: Potential Novel Molecules Against Viral Hepatitis, Research in Pharmaceutical Sciences (2017)
79. Synthesis and Characterization of Insulin/Zirconium Phosphate@Tio2 Hybrid Composites for Enhanced Oral Insulin Delivery Applications, Drug Development and Industrial Pharmacy (2017)
80. The Silencing Effect of Mir-30A on Itga4 Gene Expression in Vitro: An Approach for Gene Therapy, Research in Pharmaceutical Sciences (2017)
81. The Silencing Effect of Mir-30A on Itga4 Gene Expression in Vitro: An Approach for Gene Therapy, Research in Pharmaceutical Sciences (2017)
82. Antiproliferative Effect of a Synthetic Aptamer Mimicking Androgen Response Elements in the Lncap Cell Line, Cancer Gene Therapy (2016)
83. Exposition of Hepatitis B Surface Antigen (Hbsag) on the Surface of Hek293t Cell and Evaluation of Its Expression, Research in Pharmaceutical Sciences (2016)
84. Targeted Delivery of Doxorubicin to Breast Cancer Cells by Magnetic Lhrh Chitosan Bioconjugated Nanoparticles, International Journal of Biological Macromolecules (2016)
85. Cytotoxic Evaluation of Volatile Oil From Descurainia Sophia Seeds on Mcf-7 and Hela Cell Lines, Research in Pharmaceutical Sciences (2015)
86. Cytotoxicity and Antiangiogenic Effects of Rhus Coriaria, Pistacia Vera and Pistacia Khinjuk Oleoresin Methanol Extracts, Research in Pharmaceutical Sciences (2015)
87. Methotrexate-Grafted-Oligochitosan Micelles As Drug Carriers: Synthesis and Biological Evaluations, Journal of Materials Science: Materials in Medicine (2015)
88. In Vitro Cytotoxicity Studies of Palladacyclic Complexes Containing the Symmetric Diphosphine Bridging Ligand. Studies of Their Interactions With Dna and Bsa, European Journal of Medicinal Chemistry (2014)
89. Nanofibrous Chitosan-Polyethylene Oxide Engineered Scaffolds: A Comparative Study Between Simulated Structural Characteristics and Cells Viability, BioMed Research International (2014)
90. Cytotoxic Evaluation of Different Extracts of Taxus Baccata Against Mda-Mb-468, Hela and K562 Cancer Cell Lines, Journal of Isfahan Medical School (2013)
91. Dinuclear Bridged Biphosphinic and Mononuclear Cyclopalladated Complexes of Benzylamines: Synthesis, Structural Characterization and Antitumor Activity, Polyhedron (2013)
92. Hydroxypyridinone Derivatives: Synthesis and Cytotoxic Evaluation, Journal of Reports in Pharmaceutical Sciences (2013)
93. In Vitro Cytotoxic Evaluation of Some Synthesized Cox-2 Inhibitor Derivatives Against a Panel of Human Cancer Cell Lines, Research in Pharmaceutical Sciences (2013)
94. Effect of Molecular Weight and Molar Ratio of Dextran on Self-Assembly of Dextran Stearate Polymeric Micelles As Nanocarriers for Etoposide, Journal of Nanomaterials (2012)
95. Prevalence and Risk Factors of Hiv, Syphilis, Hepatitis B and C Among Female Prisoners in Isfahan, Iran, Hepatitis Monthly (2012)
96. Synthesis and Cytotoxic Evaluation of Some Novel Sulfonamide Derivatives Against a Few Human Cancer Cells, Iranian Journal of Pharmaceutical Research (2011)