Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Malleatin a and B: New Premyrsine-Type Diterpenes From Euphorbia Malleata With Cytotoxic Effects Against A2780 Wild and A2780 R-Cis Ovarian Cancer Cell Lines in Mono or Combination Treatment With Cisplatin
Fatemeh Shafiee
Fatemeh Shafiee

Associate Professor of Pharmaceutical Biotechnology

Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences

Isfahan University of Medical Sciences

All Documents
1. Apoptosis-Inducing Proteins With Reduced Expression in Breast Cancer: A Review Article, Biochemistry and Biophysics Reports (2025)
2. An Investigation to Find the Correlation Between Lupus Anticoagulant and Coagulation Abnormalities in Covid-19 Patients; a Narrative Review, Journal of Nephropathology (2024)
3. Dna Fragmentation Factor 40-Based Therapeutic Approaches for Cancer: A Review Article, Medical Oncology (2024)
4. Intein Based Fusion Proteins: Great Tags for the Soluble Production and Convenient Purification of Recombinant Proteins, Iranian Journal of Biotechnology (2024)
5. Kinetic Studies, Molecular Docking, and Antioxidant Activity of Novel 1,3-Diphenyl Pyrazole-Thiosemicarbazone With Anti-Tyrosinase and Anti-Melanogenesis Properties, Bioorganic Chemistry (2024)
6. Kinetic Studies, Molecular Docking, and Antioxidant Activity of Novel 1,3-Diphenyl Pyrazole-Thiosemicarbazone With Anti-Tyrosinase and Anti-Melanogenesis Properties, Bioorganic Chemistry (2024)
7. Optimization of the Production of Soluble Recombinant Tev Protease in Two E. Coli Strains, Avicenna Journal of Medical Biotechnology (2024)
8. Production of Recombinant Dna Fragmentation Factor 40 in Fusion to an Antimicrobial Peptide From Spider Venom and Evaluation of Its Cytotoxic Effects, Research in Pharmaceutical Sciences (2024)
9. Recombinant Production of Interleukin-1 Receptor Antagonist in Fusion to Albumin Binding Domain With Potential Affinity to Human Serum Albumin, Research in Pharmaceutical Sciences (2024)
10. Recombinant Production of Tp4-Lyc1, a New Chimeric Peptide With Targeted Cytotoxicity to Hela Cells, Avicenna Journal of Medical Biotechnology (2024)
11. Andrographolide Protects Against Doxorubicin-And Arsenic Trioxide-Induced Toxicity in Cardiomyocytes, Molecular Biology Reports (2023)
12. Arsenic Polyoxotungstate-Zeolitic Imidazolate Framework-8 As a Potential Selective Anti-Cancer Nano Platform, Journal of Inorganic and Organometallic Polymers and Materials (2023)
13. Design and Construction of Scfv-Pe35kdel As a Novel Immunotoxin Against Human Epidermal Growth Factor Receptor 2 for Cancer Therapy, Biotechnology Letters (2023)
14. Development and Evaluation of Wafer Loaded With Sertaconazole Solid Dispersion for the Treatment of Oral Candidiasis, Brazilian Journal of Pharmaceutical Sciences (2023)
15. Invasive Fungal Infections in Hematologic Malignancies: Incidence, Management, and Antifungal Therapy, Journal of Research in Medical Sciences (2023)
16. Invasive Fungal Infections in Hematologic Malignancies: Incidence, Management, and Antifungal Therapy, Journal of Research in Medical Sciences (2023)
17. Preparation and in Vitro Evaluation of Inhalation Powder Containing Fluconazole Nanoparticles for the Treatment of Fungal Lung Infections, Journal of Isfahan Medical School (2023)
18. The Antimicrobial Effects of Tp4-Lyc1 Fusion Protein Against Multidrug-Resistant A. Baumannii, Journal of Isfahan Medical School (2023)
19. The Effectiveness of Colistin/Levofloxacin Compared to Colistin/Meropenem in the Treatment of Ventilator-Associated Pneumonia (Vap) Caused by Carbapenem-Resistant Acinetobacter Baumannii: A Randomized Controlled Clinical Trial, Research in Pharmaceutical Sciences (2023)
20. Antibiotic Resistance Pattern of Helicobacter Pylori Strains Isolated From Patients in Isfahan, Iran, Journal of Research in Medical Sciences (2022)
21. Br2, a Buforin Derived Cancer Specific Cell Penetrating Peptide for Targeted Delivering of Toxic Agents: A Review Article, International Journal of Peptide Research and Therapeutics (2022)
22. Cytotoxic and Apoptotic Effects of Flavonoids and a Geraniol Derivative From Artemisia Kermanensis on Normal and Breast Cancer Cell Lines, Research Journal of Pharmacognosy (2022)
23. Cytotoxicity and Apoptosis Assay of Novel Cyclomyrsinol Diterpenes Against Breast Cancer Cell Lines, World Journal of Traditional Chinese Medicine (2022)
24. In Vitro Evaluation the Anti-Melanogenic Effects of Various Extracts of Oat Seeds, Iranian Journal of Pharmaceutical Sciences (2022)
25. Internalizing Rgd, a Great Motif for Targeted Peptide and Protein Delivery: A Review Article, Drug Delivery and Translational Research (2022)
26. L-Carnitine Supplementation Ameliorates Insulin Resistance in Critically Ill Acute Stroke Patients: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial, Research in Pharmaceutical Sciences (2022)
27. Pramlintide: An Amylin Analogue Protects Endothelial Cells Against Oxidative Stress Through Regulating Oxidative Markers and Nf-Κb Expression, International Journal of Preventive Medicine (2022)
28. Rational Design of a New Variant of Reteplase With Optimized Physicochemical Profile and Large-Scale Production in Escherichia Coli, World Journal of Microbiology and Biotechnology (2022)
29. Recombinant Production of a Mutant Form of Soluble Il-6 Receptor With Inhibitory Effects Against Interleukin-6, Iranian Journal of Biotechnology (2022)
30. An Innovative Approach to Fabricate a Thermosensitive Melatonin-Loaded Conductive Pluronic/Chitosan Hydrogel for Myocardial Tissue Engineering, Journal of Applied Polymer Science (2021)
31. Antimicrobial Susceptibility Pattern of Carbapenemase-Producing Gram-Negative Nosocomial Bacteria at Al Zahra Hospital, Isfahan, Iran, Iranian Journal of Microbiology (2021)
32. Corrigendum To: “Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications” [Biomed. Pharmacother. 139 (2021) 111599] (Biomedicine & Pharmacotherapy (2021) 139, (S075333222100384x), (10.1016/J.Biopha.2021.111599)), Biomedicine and Pharmacotherapy (2021)
33. Corrigendum To: “Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications” [Biomed. Pharmacother. 139 (2021) 111599] (Biomedicine & Pharmacotherapy (2021) 139, (S075333222100384x), (10.1016/J.Biopha.2021.111599)), Biomedicine and Pharmacotherapy (2021)
34. Cytotoxicity and Apoptosis Inducing Effects of Some Lathyrane and Tigliane Diterpenes Against Breast Cancer Cell Lines, Traditional and Integrative Medicine (2021)
35. Dff40-Irgd, a Novel Chimeric Protein With Efficient Cytotoxic and Apoptotic Effects Against Triple-Negative Breast Cancer Cells, Biotechnology Letters (2021)
36. In Vitro Synergistic Effect of Colistin and Ampicillin/Sulbactam With Several Antibiotics Against Clinical Strains of Multi-Drug Resistant Acinetobacter Baumannii, Indian Journal of Medical Microbiology (2021)
37. Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications, Biomedicine and Pharmacotherapy (2021)
38. Novel and Emerging Mutations of Sars-Cov-2: Biomedical Implications, Biomedicine and Pharmacotherapy (2021)
39. Recombinant Production and One-Step Purification of Il-1Ra in Escherichia Coli and Evaluation of Its Il-1 Antagonizing Efficacy, Iranian Journal of Immunology (2021)
40. Survivin Promoter-Driven Dff40 Gene Expression Sensitizes Melanoma Cancer Cells to Chemotherapy, International Journal of Toxicology (2021)
41. Coenzyme Q10 Improves the Survival and Reduces Inflammatory Markers in Septic Patients, Bratislava Medical Journal (2020)
42. Evaluation of Cytotoxic and Apoptotic Effects of Dt386-Br2: A Promising Anticancer Fusion Protein, Journal of Reports in Pharmaceutical Sciences (2020)
43. Expression and One Step Intein-Mediated Purification of Biologically Active Human G-Csf in Escherichia Coli, Molecular Biology Reports (2020)
44. In Silico Design of Two Novel Fusion Proteins, P28-Il-24 and P28-M4, Targeted to Breast Cancer Cells, Research in Pharmaceutical Sciences (2020)
45. Persicoimidate Isolated From Allium Ampeloprasum Subsp. Persicum With Apoptotic Effects Against Breast Cancer Cell Lines, Iranian Journal of Pharmaceutical Sciences (2020)
46. Expression, Purification, and Cytotoxic Evaluation of Il24-Br2 Fusion Protein, Research in Pharmaceutical Sciences (2019)
47. Targeted Diphtheria Toxin-Based Therapy: A Review Article, Frontiers in Microbiology (2019)
48. Introduction of a Novel Cancer Cell Targeted Fusion Protein: Dt386-Br2, Annals of Oncology (2018)
49. In-Vivo Evaluation of Dt386-Br2, a Promising Anticancer Fusion Protein, in Mice Model, Journal of Isfahan Medical School (2017)
50. Recombinant Production and Intein-Mediated Purification of an Antimicrobial Peptide, Br2, International Journal of Peptide Research and Therapeutics (2017)
51. Expression and Purification of Truncated Diphtheria Toxin, Dt386, in Escherichia Coli: An Attempt for Production of a New Vaccine Against Diphtheria, Research in Pharmaceutical Sciences (2016)
52. Production and Evaluation of Cytotoxic Effects of Dt386-Br2 Fusion Protein As a Novel Anti-Cancer Agent, Journal of Microbiological Methods (2016)
53. Isolation and Characterization of a New Thermoalkalophilic Lipase From Soil Bacteria, Iranian Journal of Pharmaceutical Research (2015)
54. Optimization of the Expression of Reteplase in Escherichia Coli Top10 Using Arabinose Promoter, Jundishapur Journal of Natural Pharmaceutical Products (2015)