Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Dual Drug Delivery System of Plga Nanoparticles to Reverse Drug Resistance by Altering Bax/Bcl-2
Mohammad Reza Khoshayand
Mohammad Reza Khoshayand

Associate Professor of Pharmaceuticals, Cosmetics and Toiletries Control

Department Food and Drug Control

School of Pharmacy

Pharmaceutical Sciences Research Center

Tehran University of Medical Sciences

Related Documents
1. Dual Drug Delivery System of Plga Nanoparticles to Reverse Drug Resistance by Altering Bax/Bcl-2, Journal of Drug Delivery Science and Technology (2018)
All Documents
1. Metal-Organic Frameworks Mil-101(Fe) and Mil-53(Al) As Efficient Adsorbents for Dispersive Micro-Solid-Phase Extraction of Sorafenib in Plasma and Wastewater, Coupled With Hplc-Uv Analysis, Journal of Chromatographic Science (2025)
2. Optimization of Mangiferin From Mango (Mangifera Indica L.) Leaves Using Response Surface Methodology, Jundishapur Journal of Natural Pharmaceutical Products (2025)
3. Characterization and Genome Analysis of a Broad Host Range Lytic Phage Vb_Sens_Tums_E19 Against Salmonella Enterica and Its Efficiency Evaluation in the Liquid Egg, Canadian Journal of Microbiology (2024)
4. Comparative Study of Dispersive Micro-Solid Phase Extraction of Nandrolone Using Mil-53(Al) and Zif-8 in Human Plasma, Journal of Analytical Chemistry (2024)
5. Comparison of Testosterone Extraction From Human Plasma Using Mofs (Mil-53(Al) and Zif-8)-Based D-Μ-Spe Coupled to Hplc–Uv, Chromatographia (2024)
6. Detecting Olive Oil Fraud With Near-Infrared Spectroscopy and Chemometrics: A Modern Safety Control Approach, Jundishapur Journal of Natural Pharmaceutical Products (2024)
7. Development of Non-Destructive Methods for the Assessment of Authenticity of Sports Whey Protein Supplements, Food Additives and Contaminants - Part A (2024)
8. Development, Optimization, and Characterization of Vitamin C-Fortified Oleogel-Based Chewable Gels and a Novel Nondestructive Analysis Method for the Vitamin C Assay, Food Production, Processing and Nutrition (2024)
9. Dispersive Micro-Solid Phase Extraction Based on Two Mofs As Highly Effective Adsorbents for Analysis of Nilotinib in Plasma and Wastewater, DARU, Journal of Pharmaceutical Sciences (2024)
10. Corrigendum to “Dual Drug Delivery System of Plga Nanoparticles to Reverse Drug Resistance by Altering Bax/Bcl-2” [J. Drug Deliv. Sci. Technol. 47 (2018) 291–298, (S1773224718301825), (10.1016/J.Jddst.2018.07.019)], Journal of Drug Delivery Science and Technology (2023)
11. Design of Experiments Approach for the Development of a Validated Method to Determine the Exenatide Content in Poly(Lactide-Co-Glycolide) Microspheres, European Journal of Pharmaceutics and Biopharmaceutics (2023)
12. Evaluation of Important Human Cyp450 Isoforms and P-Glycoprotein Phenotype Changes and Genotype in Type 2 Diabetic Patients, Before and After Intensifying Treatment Regimen Using Geneva Cocktail, Basic and Clinical Pharmacology and Toxicology (2023)
13. Identification and Quantification of Ciprofloxacin, Enrofloxacin and Difloxacin Residues in Milk Using Excitation-Emission Fluorescence and Second-Order Standard Addition Methods, Chemometrics and Intelligent Laboratory Systems (2023)
14. Impact of Obesity and Bariatric Surgery on Metabolic Enzymes and P-Glycoprotein Activity Using the Geneva Cocktail Approach, Journal of Personalized Medicine (2023)
15. Isolation, Characterization, and Genome Analysis of a Broad Host Range Salmonella Phage Vb_Sens_Tums_E4: A Candidate Bacteriophage for Biocontrol, Veterinary Research Communications (2023)
16. Isolation, Characterization, and Genomic Analysis of Vb_Paep_Tums_P121, a New Lytic Bacteriophage Infecting Pseudomonas Aeruginosa, Archives of Virology (2023)
17. Isolation, Characterization, and Genomic Analysis of Vb_Paes_Tums_P81, a Lytic Bacteriophage Against Pseudomonas Aeruginosa, Virus Genes (2023)
18. The Optimization of Fenugreek Seeds (Trigonella Foenum-Graecum L.) Extraction by Response Surface Methodology Based on Β-Sitosterol, Journal of Medicinal Plants (2023)
19. Detection and Quantification of Adulteration in Turmeric by Spectroscopy Coupled With Chemometrics, Journal fur Verbraucherschutz und Lebensmittelsicherheit (2022)
20. Formulation, Characterization, and Bioactivity Assessments of a Laccase-Based Mouthwash, Journal of Drug Delivery Science and Technology (2022)
21. Green Synthesis, Characterization, and Biological Evaluation of Hydroxyl-Capped Tellurium Nanoparticles, Journal of Sciences# Islamic Republic of Iran (2022)
22. Multivariate Analysis of Food Fraud: A Review of Nir Based Instruments in Tandem With Chemometrics, Journal of Food Composition and Analysis (2022)
23. Bisphenol-A in Biological Samples of Breast Cancer Mastectomy and Mammoplasty Patients and Correlation With Levels Measured in Urine and Tissue, Scientific Reports (2021)
24. Development of an Enzyme-Enhancer System to Improve Laccase Biological Activities, International Journal of Biological Macromolecules (2021)
25. Optimization of Chitosan-Based Polyelectrolyte Nanoparticles for Gene Delivery, Using Design of Experiment: In Vitro and in Vivo Study, Materials Science and Engineering C (2021)
26. Potential of Chitosan/Alginate Nanoparticles As a Non-Viral Vector for Gene Delivery: Formulation and Optimization Using D-Optimal Design, Materials Science and Engineering C (2021)
27. Analysis of Residual Moisture in a Freeze-Dried Sample Drug Using a Multivariate Fitting Regression Model, Microchemical Journal (2020)
28. Combination of Thermal and Biological Treatments for Bio-Removal and Detoxification of Some Recalcitrant Synthetic Dyes by Betaine-Induced Thermostabilized Laccase, Environmental Technology and Innovation (2020)
29. Combining Chemometrics and the Technique for the Order of Preference by Similarity to Ideal Solution: A New Approach to Multiple-Response Optimization of Hplc Compared to Desirability Function, Microchemical Journal (2020)
30. Design of Experiment, Preparation, and in Vitro Biological Assessment of Human Amniotic Membrane Extract Loaded Nanoparticles, Current Pharmaceutical Biotechnology (2020)
31. Electromembrane Extraction of Phenytoin From Biological Fluids: A Survey on the Effects of Molecularly Imprinted Polymer and Carbon Nanotubes on Extraction Efficiency, Microchemical Journal (2020)
32. Response Surface Methodology for Statistical Optimization of Chitosan/Alginate Nanoparticles As a Vehicle for Recombinant Human Bone Morphogenetic Protein-2 Delivery, International Journal of Nanomedicine (2020)
33. Second-Order Universal Calibration, Talanta (2020)
34. Simultaneous Determination of Nine Sunscreen Agents by Hplc and Chemometric Analysis, Journal of Cosmetic Science (2019)
35. The Prevalence of the Genetic Polymorphism of Gstm1, Gstt1 and Gstp1 and Its Relationship With Clinical Criteria of Multiple Sclerosis (Ms) Patients in Tehran, Journal of Babol University of Medical Sciences (2019)
36. The Prevalence of the Genetic Polymorphism of Gstm1, Gstt1 and Gstp1 and Its Relationship With Clinical Criteria of Multiple Sclerosis (Ms) Patients in Tehran, Journal of Babol University of Medical Sciences (2019)
37. Applications and Opportunities of Experimental Design for the Dispersive Liquid–Liquid Microextraction Method – a Review, Talanta (2018)
38. Characterization and Classification of Iranian Honey Based on Physicochemical Properties and Antioxidant Activities, With Chemometrics Approach, Iranian Journal of Pharmaceutical Research (2018)
39. Characterization of Folic Acid Surface-Coated Selenium Nanoparticles and Corresponding in Vitro and in Vivo Effects Against Breast Cancer, Archives of Medical Research (2018)
40. Determination of Biological Activity of Recombinant Reteplase Using Clot Lysis Time and Activated Partial Thromboplastin Time (Aptt) Lysis Methods: A Comparative Study, Iranian Journal of Pharmaceutical Research (2018)
41. Dual Drug Delivery System of Plga Nanoparticles to Reverse Drug Resistance by Altering Bax/Bcl-2, Journal of Drug Delivery Science and Technology (2018)
42. Effect of Powder Sizes, Ph of Water, Ultrasound and Method of Distillation on Extraction of Fennel Essential Oil and Anethole Content, Iranian Journal of Pharmaceutical Sciences (2018)
43. Enhanced Production and Characterization of a Highly Stable Extracellular Protease From an Extreme Halophilic Isolate Salicola Marasensis, Iranian Journal of Pharmaceutical Research (2018)
44. Ocular Implant Containing Bevacizumab-Loaded Chitosan Nanoparticles Intended for Choroidal Neovascularization Treatment, Journal of Biomedical Materials Research - Part A (2018)
45. Optimization of Rpdt Fusion Protein Expression by Escherichia Coli in Pilot Scale Fermentation: A Statistical Experimental Design Approach, AMB Express (2018)
46. Prolonged Injectable Formulation of Nafarelin Using in Situ Gel Combination Delivery System, Pharmaceutical Development and Technology (2018)
47. Application of Polyaniline–Multiwalled Carbon Nanotubes Composite Fiber for Determination of Benzaldehyde in Injectable Pharmaceutical Formulations by Solid-Phase Microextraction Gc–Fid Using Experimental Design, Journal of Analytical Chemistry (2017)
48. Correlation Between Heavy Metal Exposure and Gstm1 Polymorphism in Iranian Multiple Sclerosis Patients, Neurological Sciences (2017)
49. Correlation Between Heavy Metal Exposure and Gstm1 Polymorphism in Iranian Multiple Sclerosis Patients, Neurological Sciences (2017)
50. Delignification and Detoxification of Peanut Shell Bio-Waste Using an Extremely Halophilic Laccase From an Aquisalibacillus Elongatus Isolate, Extremophiles (2017)
51. Detection of Adulteration in Iranian Saffron Samples by 1H Nmr Spectroscopy and Multivariate Data Analysis Techniques, Metabolomics (2017)
52. Effect of Nonionic Surfactants (Dodecyl Maltoside and Polysorbate 20) on Prevention of Aggregation and Conformational Changes of Recombinant Human Ifnβ_1B Induced by Light, Iranian Journal of Pharmaceutical Research (2017)
53. Improved Production and Characterization of a Highly Stable Laccase From the Halophilic Bacterium Chromohalobacter Salexigens for the Efficient Delignification of Almond Shell Bio-Waste, International Journal of Biological Macromolecules (2017)
54. Nanoparticulate Fingolimod Delivery System Based on Biodegradable Poly (3-Hydroxybutyrate-Co-3-Hydroxyvalerate) (Phbv): Design, Optimization, Characterization and In-Vitro Evaluation, Pharmaceutical Development and Technology (2017)
55. Screening for Type Ii L-Asparaginases: Lessons From the Genus Halomonas, Iranian Journal of Pharmaceutical Research (2017)
56. Biocatalytic Conversion and Detoxification of Imipramine by the Laccase-Mediated System, International Biodeterioration and Biodegradation (2016)
57. Blood Concentrations of Cadmium and Lead in Multiple Sclerosis Patients From Iran, Iranian Journal of Pharmaceutical Research (2016)
58. Fabrication and Biological Evaluation of Chitosan Coated Hyaluronic Acid-Docetaxel Conjugate Nanoparticles in Cd44+ Cancer Cells, DARU# Journal of Pharmaceutical Sciences (2016)
59. L-Asparaginase Activity in Cell Lysates and Culture Media of Halophilic Bacterial Isolates, Iranian Journal of Pharmaceutical Research (2016)
60. Preparation of a New Nanoparticle Cd(Ii)-Imprinted Polymer and Its Application for Selective Separation of Cadmium(Ii) Ions From Aqueous Solutions and Determination Via Inductively Coupled Plasma Optical Emission Spectrometry, Desalination and Water Treatment (2016)
61. Biosynthesis of Tellurium Nanoparticles by Lactobacillus Plantarum and the Effect of Nanoparticle-Enriched Probiotics on the Lipid Profiles of Mice, IET Nanobiotechnology (2015)
62. Chitosan Polyplex Nanoparticle Vector for Mir-145 Expression in Mcf-7: Optimization by Design of Experiment, International Journal of Biological Macromolecules (2015)
63. Controlled Release of Rhegf and Rhbfgf From Electrospun Scaffolds for Skin Regeneration, Journal of Biomedical Materials Research - Part A (2015)
64. Effects of Heating and Acidic Solutions of Vinegar and Oxymel on Milk Coagulation for Identification and Quantification of Resulting Α-Lactalbumin and Β-Lactoglobulin Proteins in the Final Whey Product, Analytical Chemistry Letters (2015)
65. Efficient Decolorization and Detoxification of Reactive Orange 7 Using Laccase Isolated From Paraconiothyrium Variabile, Kinetics and Energetics, Journal of the Taiwan Institute of Chemical Engineers (2015)
66. Isolation and Structural Characterization of Coryxin, a Novel Cyclic Lipopeptide From Corynebacterium Xerosis Ns5 Having Emulsifying and Anti-Biofilm Activity, Colloids and Surfaces B: Biointerfaces (2015)
67. Laccase-Catalyzed Decolorization and Detoxification of Acid Blue 92: Statistical Optimization, Microtoxicity, Kinetics, and Energetics, Journal of Environmental Health Science and Engineering (2015)
68. Medium-Based Optimization of an Organic Solvent-Tolerant Extracellular Lipase From the Isolated Halophilic Alkalibacillus Salilacus, Extremophiles (2015)
69. Preventing Aggregation of Recombinant Interferon Beta-1B in Solution by Additives: Approach to an Albumin-Free Formulation, Advanced Pharmaceutical Bulletin (2015)
70. Ciprofloxacin Loaded Alginate/Chitosan and Solid Lipid Nanoparticles, Preparation, and Characterization, Journal of Dispersion Science and Technology (2012)
71. Optimization of Freeze-Drying Condition of Amikacin Solid Lipid Nanoparticles Using D-Optimal Experimental Design, Pharmaceutical Development and Technology (2012)
72. Development and Optimization of Solid Lipid Nanoparticles of Amikacin by Central Composite Design, Journal of Liposome Research (2010)