Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Immunization With a Novel Chimeric Peptide Representing B and T Cell Epitopes From Her2 Extracellular Domain (Her2 Ecd) for Breast Cancer
Abbas Jafarian
Abbas Jafarian

Professor of Pharmacology

Department of Pharmacology and Toxicology, School of Pharmacy and Pharmaceutical Sciences

Isfahan University of Medical Sciences

All Documents
1. Toxicity Effect of Hypnea Flagelliformis Algae on Cancerous Mitochondria Obtained From Rat Model of Hepatocellular Carcinoma, Asian Pacific Journal of Cancer Prevention (2024)
2. The Effects of Astragalus Polysaccharides, Tragacanthin, and Bassorin on Methotrexate-Resistant Acute Lymphoblastic Leukemia, Research in Pharmaceutical Sciences (2023)
3. Modulatory Effects of Dexrazoxane Against Genotoxicity and Lipid Peroxidation Induced by Idarubicin in Hepg2 Cells, International Journal of Cancer Management (2018)
4. Magnetic Polyvinyl Caprolactam–Polyvinyl Acetate–Polyethylene Glycol Micelles for Docetaxel Delivery in Breast Cancer: An in Vitro Study on Two Cell Lines of Breast Cancer, Pharmaceutical Development and Technology (2017)
5. Protective Effect of Amifostine on Busulfan Induced Dna Damage in Human Hepatoma Cells, Toxicology Mechanisms and Methods (2017)
6. Study of the Role of Sirna Mediated Promoter Methylation in Dnmt3b Knockdown and Alteration of Promoter Methylation of Cdh1, Gstp1 Genes in Mda-Mb -453 Cell Line, Iranian Journal of Pharmaceutical Research (2017)
7. A Comparison of the Effect of Certain Inorganic Salts on Suppression Acute Skin Irritation by Human Biometric Assay: A Randomized, Double-Blind Clinical Trial, Journal of Research in Medical Sciences (2016)
8. Biomimetic Proopiomelanocortin Suppresses Capsaicin-Induced Sensory Irritation in Humans, Research in Pharmaceutical Sciences (2016)
9. Cytotoxic Effects of Pinus Eldarica Essential Oil and Extracts on Hela and Mcf-7 Cell Lines, Research in Pharmaceutical Sciences (2016)
10. Lovastatin Prevents Bleomycin-Induced Dna Damage to Hepg2 Cells, Research in Pharmaceutical Sciences (2016)
11. Optimization of Vasopressin Type 2 Receptor Expression in Escherichia Coli Bl21, Jundishapur Journal of Natural Pharmaceutical Products (2016)
12. Role of Recombinant Human Erythropoietin Loading Chitosan-Tripolyphosphate Nanoparticles in Busulfan-Induced Genotoxicity: Analysis of Dna Fragmentation Via Comet Assay in Cultured Hepg2 Cells, Toxicology in Vitro (2016)
13. The Effect of Persian Juniperus Excelsa Extracts on Cell-Cycle Phases of Mcf-7 Breast Cancer Cell Line, Journal of Isfahan Medical School (2016)
14. Evaluation of Genoprotective Effects of Hydroalcoholic and Polyphenolic Extracts of Quince by Comet Assay, Journal of Reports in Pharmaceutical Sciences (2015)
15. Evaluation of Protective Effect of Amifostine on Dacarbazine Induced Genotoxicity, Research in Pharmaceutical Sciences (2015)
16. Evaluation of the Genoprotective Effect of Polyphenolic, Hydroalcoholic and Aqueous Extracts of Red Apple, Toxicology International (2015)
17. Improved Biological Activity of a Single Chain Antibody Fragment Against Human Epidermal Growth Factor Receptor 2 (Her2) Expressed in the Periplasm of Escherichia Coli, Protein Expression and Purification (2015)
18. Optimization of a Single-Chain Antibody Fragment Overexpression in Escherichia Coli Using Response Surface Methodology, Research in Pharmaceutical Sciences (2015)
19. Production and Characterization of New Anti-Her2 Monoclonal Antibodies, Monoclonal Antibodies in Immunodiagnosis and Immunotherapy (2015)
20. Assessment of the Deoxyribonucleic Acid Damage Caused by Occupational Exposure to Chemical Compounds in Isfahan Polyacryl Company, Journal of Research in Medical Sciences (2014)
21. Comparing Different Sterol Containing Solid Lipid Nanoparticles for Targeted Delivery of Quercetin in Hepatocellular Carcinoma, Journal of Liposome Research (2014)
22. Cytotoxic Effects of Chloroform and Hydroalcoholic Extracts of Aerial Parts of Cuscuta Chinensis and Cuscuta Epithymum on Hela, Ht29 and Mda-Mb-468 Tumor Cells, Research in Pharmaceutical Sciences (2014)
23. Functional Expression of a Single-Chain Antibody Fragment Against Human Epidermal Growth Factor Receptor 2 (Her2) in Escherichia Coli, Journal of Industrial Microbiology and Biotechnology (2014)
24. Immunization With a Novel Chimeric Peptide Representing B and T Cell Epitopes From Her2 Extracellular Domain (Her2 Ecd) for Breast Cancer, Tumor Biology (2014)
25. Phytoremediation of Benzene, Toluene, Ethylbenzene and Xylene Contaminated Air by D. Deremensis and O. Microdasys Plants, Journal of Environmental Health Science and Engineering (2014)
26. Antigenotoxic Effects of Methanolic and Aqueous Extracts of Kelussia Odoratissima Mozaffarian Against Damage Induced by Methyl Methanesulfonate, Journal of Isfahan Medical School (2013)
27. Biodistribution of Amikacin Solid Lipid Nanoparticles After Pulmonary Delivery, BioMed Research International (2013)
28. Comparison of Bleomycin-Induced Pulmonary Apoptosis Between Nmri Mice and C57bl/6 Mice, Research in Pharmaceutical Sciences (2013)
29. Heavy Metal Contamination of Vegetables in Isfahan, Iran, Research in Pharmaceutical Sciences (2013)
30. Hypnotic Effect of Salvia Reuterana Boiss for Treatment of Insomnia, Journal of Medicinal Plants (2013)
31. In Silico Design of Discontinuous Peptides Representative of B and T-Cell Epitopes From Her2-Ecd As Potential Novel Cancer Peptide Vaccines, Asian Pacific Journal of Cancer Prevention (2013)
32. In Vitro Anti-Bacterial and Anti-Adherence Effects of Lactobacillus Delbrueckii Subsp Bulgaricus on Escherichia Coli, Research in Pharmaceutical Sciences (2013)
33. Preventive Effect of Cinnamon Essential Oil on Lipid Oxidation of Vegetable Oil, ARYA Atherosclerosis (2013)
34. Quantitative Evaluation of Dnmt3b Promoter Methylation in Breast Cancer Patients Using Differential High Resolution Melting Analysis, Research in Pharmaceutical Sciences (2013)
35. The Effects of Chloroform, Ethyl Acetate and Methanolic Extracts of Brassica Rapa L. on Cell-Mediated Immune Response in Mice, Research in Pharmaceutical Sciences (2013)
36. Determination of Aflatoxin M1 in Breast Milk Samples in Isfahan, Iran, Journal of Isfahan Medical School (2012)
37. Does the Tissue Engineering Architecture of Poly(3-Hydroxybutyrate) Scaffold Affects Cell-Material Interactions?, Journal of Biomedical Materials Research - Part A (2012)
38. Evaluation of Dna Damage of Hydro-Alcoholic and Aqueous Extract of Echium Amoenum and Nardostachys Jatamansi, Journal of Research in Medical Sciences (2012)
39. Genotoxic Effects of Some L-[(Benzofuran-2-Yl)-Phenylmethyl]-Imidazoles on Mcf-7 Cell Line, Research in Pharmaceutical Sciences (2012)
40. Genotoxicity Evaluation of Aqueous Extracts of Cotoneaster Discolor and Alhagi Pseudalhagi by Comet Assay, Journal of Research in Medical Sciences (2012)
41. Linear and Conformational B Cell Epitope Prediction of the Her 2 Ecd-Subdomain Iii by in Silico Methods, Asian Pacific Journal of Cancer Prevention (2012)
42. Optimization of Freeze-Drying Condition of Amikacin Solid Lipid Nanoparticles Using D-Optimal Experimental Design, Pharmaceutical Development and Technology (2012)
43. Targeting Etoposide to Acute Myelogenous Leukaemia Cells Using Nanostructured Lipid Carriers Coated With Transferrin, Nanotechnology (2012)
44. The Effects of Methanolic, Chloroform, and Ethylacetate Extracts of the Cucurbita Pepo L. on the Delay Type Hypersensitivity and Antibody Production, Research in Pharmaceutical Sciences (2012)
45. Mutation of the Histidin Residue of the Drh Motif in Vasopressin V2 Receptor Expression and Function, DARU, Journal of Pharmaceutical Sciences (2010)
46. The Effect of Aspartate-Lysine-Isoleucine and Aspartate-Arginine-Tyrosine Mutations on the Expression and Activity of Vasopressin V2 Receptor Gene, Iranian Biomedical Journal (2010)
47. Effect of Long-Lasting Phenobarbital Administration on the Volume of Hippocampal Regions in Rat, Journal of Isfahan Medical School (2009)
48. Evaluation of in Vitro Cytotoxic Effects of Juniperus Foetidissima and Juniperus Sabina Extracts Against a Panel of Cancer Cells, Iranian Journal of Pharmaceutical Research (2009)
49. The Effect of At1 Receptor Blockade on Bax and Bcl-2 Expression in Bleomycin-Induced Pulmonary Fibrosis, Daru (2009)
50. A Comparison Between Osteogenic Index, Gross and Skeletal Abnormalities in the Embryo of Treated Mice With Herbal Lavandula Officinalis and Those With Chemical Phenytoin Antiepileptic Drugs, Journal of Applied Animal Research (2008)
51. A New Spectrophotometric Method for Direct Determination of Iron (Iii) in Serum, Daru (2008)
52. Identification of an Isolate of Pseudomonas Aeroginosa Deposited in Ptcc As a Pha Producer Strain: Comparison of Three Different Bacterial Genomic Dna Extraction Methods, Journal of Biological Sciences (2008)
53. The Role of Strain Variation in Bax and Bcl-2 Expression in Murine Bleomycin-Induced Pulmonary Fibrosis, Pakistan Journal of Biological Sciences (2008)
54. Development and Time-Course of Bleomycin-Induced Pulmonary Fibrosis in Nmri Mice, Daru (2007)
55. Colon-Specific Delivery of Mesalazine Chitosan Microspheres, Journal of Microencapsulation (2006)
56. Effects of Silymarin on the Proliferation and Glutathione Levels of Peripheral Blood Mononuclear Cells From Β-Thalassemia Major Patients, International Immunopharmacology (2006)
57. Pneumonia Associated With a Single Intratracheal Dose of Bleomycin in Mice, Lab Animal (2006)
58. Anxiolytic Effects of Salvia Reuterana Boiss. on the Elevated Plus-Maze Model of Anxiety in Mice, Journal of Ethnopharmacology (2005)
59. Characterization of the Monoclonal Anti-Substance P Antibody Derived From Nc1/34, Medical Journal of the Islamic Republic of Iran (2005)
60. Cytotoxic Effects of Essential Oils of Some Iranian Citrus Peels, Iranian Journal of Pharmaceutical Research (2005)
61. Cytotoxic Evaluations of Iranian Conifers on Cancer Ells, Pharmaceutical Biology (2005)
62. Fibrinolytic Effects of Ginkgo Biloba Extract, Experimental and Clinical Cardiology (2005)
63. Acute and Chronic Effects of Nitrendipine on Naloxone Precipitated Morphine Withdrawal in Mice, Iranian Journal of Pharmaceutical Research (2004)
64. Anxiolytic Effects of Echium Amoenum on the Elevated Plus-Maze Model of Anxiety in Mice, Fitoterapia (2004)
65. Optimization of Enzymatic Synthesis of Ampicillin Using Cross-Linked Aggregates of Penicillin G Acylase, Iranian Journal of Pharmaceutical Research (2004)
66. Cytotoxic Effects of the Extracts of Iranian Taxus Baccata and Cupressus Horizentalis on Cancer Cells, Iranian Journal of Pharmaceutical Research (2003)
67. Pharmacologic Characterization of Bronchospasm Induced by Substance P (Sp) and Sp Fragments in Guinea-Pig, Daru (2003)
68. The Effects of Allium Hirtifolium Boiss. on Cell-Mediated Immune Response in Mice, Iranian Journal of Pharmaceutical Research (2003)