Isfahan University of Medical Sciences

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Faculty Members have conducted research related to the Optimization of the Basal Medium for Improving Production and Secretion of Taxanes From Suspension Cell Culture of Taxus Baccata L
Mohammad Reza Mofid
Mohammad Reza Mofid

Professor of Clinical Biochemistry

Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences

Bioinformatics Research Center

Isfahan University of Medical Sciences

All Documents
1. Role of Igfbp-3 in Human Diseases Relying on Different Cell Signaling Pathways, Advanced Biomedical Research (2025)
2. Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease, Journal of Mazandaran University of Medical Sciences (2024)
3. Clinicopathological Correlation of Insulin-Like Growth Factor Binding Protein 3 and Their Death Receptor in Patients With Gastric Cancer, Research in Pharmaceutical Sciences (2024)
4. The Human Kinome: Its Role and Importance in Cancer and the Associated Therapeutic Strategies, Journal of Babol University of Medical Sciences (2024)
5. Alleviation of Cognitive Deficits in a Rat Model of Glutamate-Induced Excitotoxicity, Using an N-Type Voltage-Gated Calcium Channel Ligand, Extracted From Agelena Labyrinthica Crude Venom, Frontiers in Molecular Neuroscience (2023)
6. Corrigendum: Alleviation of Cognitive Deficits in a Rat Model of Glutamate-Induced Excitotoxicity, Using an N-Type Voltage-Gated Calcium Channel Ligand, Extracted From Agelena Labyrinthica Crude Venom (Front. Mol. Neurosci., (2023), 16, (1123343), 10.3389/Fnmol.2023.1123343), Frontiers in Molecular Neuroscience (2023)
7. Development of a Novel and Efficient Hcdc Process for Heterologous Production of Ambystoma Mexicanum Epidermal Lipoxygenase (Ambloxe) in E. Coli, Iranian Journal of Chemistry and Chemical Engineering (2023)
8. Inhibition of Mouse Colon Cancer Growth Following Immunotherapy With a Fraction of Hydatid Cyst Fluid, Experimental Parasitology (2023)
9. Optimization of Degenerate Pcr Conditions for Reducing Error Rates in Detection of Pks and Nrps Gene Groups in Actinomycetes, Avicenna Journal of Medical Biotechnology (2023)
10. Purified Native Protein Extracted From the Venom of Agelena Orientalis Attenuates Memory Defects in the Rat Model of Glutamate-Induced Excitotoxicity, Protein Journal (2023)
11. The Synergic Effects of Presynaptic Calcium Channel Antagonists Purified From Spiders on Memory Elimination of Glutamate-Induced Excitotoxicity in the Rat Hippocampus Trisynaptic Circuit, Frontiers in Molecular Biosciences (2023)
12. Ameliorative Effects of Omega-Lycotoxin-Gsp2671e Purified From the Spider Venom of Lycosa Praegrandis on Memory Deficits of Glutamate-Induced Excitotoxicity Rat Model, Frontiers in Pharmacology (2022)
13. Blood Igms From Healthy Donors and Patients With Systemic Lupus Erythematosus Reduce the Inflammatory Properties of Platelets From Healthy Donors, Immunobiology (2022)
14. Expression of Recombinant Insulin-Like Growth Factor-Binding Protein-3 Receptor in Mammalian Cell Line and Prokaryotic (Escherichia Coli) Expression Systems, Advanced Biomedical Research (2022)
15. Anti-Cancer Immunoprotective Effects of Immunization With Hydatid Cyst Wall Antigens in a Non-Immunogenic and Metastatic Triple-Negative Murine Mammary Carcinoma Model, International Immunopharmacology (2021)
16. Efficient Process Development for High-Level Production, Purification, Formulation, and Characterization of Recombinant Mecasermin in Escherichia Coli, Biotechnology and Applied Biochemistry (2021)
17. Novel Approach to Overcome Defects of Cell-Selex in Developing Aptamers Against Aspartate Β-Hydroxylase, ACS Omega (2021)
18. The Effect of Agelena Labyrinthica Total Venom and Its Agatoxin Fraction on the Kainic Acid-Induced Cognitive Disorder in Rat, Journal of Isfahan Medical School (2021)
19. The Effect of Omega-Lycotoxin on the Cognitive Impairment Induced by Kainic Acid in Rats, Iranian Journal of Toxicology (2021)
20. Alginate Hydrogel Enriched With Ambystoma Mexicanum Epidermal Lipoxygenase-Loaded Pectin Nanoparticles for Enhanced Wound Healing, Journal of Biomaterials Applications (2020)
21. An Innovative Cell Selection Approach in Developing Human Cells Overexpressing Aspartyl/Asparaginyl Β-Hydroxylase, Research in Pharmaceutical Sciences (2020)
22. Aptamer-Based Approaches for in Vitro Molecular Detection of Cancer, Research in Pharmaceutical Sciences (2020)
23. Insulin-Like Growth Factor Binding Protein 3 Chemosensitizes Pancreatic Ductal Adenocarcinoma Through Its Death Receptor, Pancreatology (2020)
24. Purification of Soluble Membrane-Bound Ambystoma Mexicanum Epidermal Lipoxygenase From E. Coli and Its Growth Effect on Human Fetal Foreskin Fibroblast, Protein Journal (2020)
25. The Effect of Terminal Groups and Halogenation of Klvff Peptide on Its Activity As an Inhibitor of Β-Amyloid Aggregation, Journal of Peptide Science (2020)
26. Effect of Hydatid Cyst Fluid Antigens on Induction of Apoptosis on Breast Cancer Cells, Advanced Biomedical Research (2019)
27. Expression and Production of Recombinant Scorpine As a Potassium Channel Blocker Protein in Escherichia Coli, Biotechnology and Applied Biochemistry (2019)
28. Expression and Production of Recombinant Scorpine As a Potassium Channel Blocker Protein in Escherichia Coli, Biotechnology and Applied Biochemistry (2019)
29. Identifying the Most Effective Hydatid Cyst Fluid Fraction for Anticancer Vaccination of 4T1 Breast Tumor-Bearing Mice, International Journal of Preventive Medicine (2019)
30. Investigation of Factors Influencing Oxygen Content in Halobacterium Salinarum Growth Medium for Improved Bacteriorhodopsin Production, International Journal of Industrial Chemistry (2019)
31. Over-Expression of Low-Density Lipoprotein Receptor-Related Protein-1 Is Associated With Poor Prognosis and Invasion in Pancreatic Ductal Adenocarcinoma, Pancreatology (2019)
32. Over-Expression of Low-Density Lipoprotein Receptor-Related Protein-1 Is Associated With Poor Prognosis and Invasion in Pancreatic Ductal Adenocarcinoma, Pancreatology (2019)
33. The Insulin-Like Growth Factor Binding Protein-3 and Its Death Receptor in Pancreatic Ductal Adenocarcinoma Poor Prognosis, Journal of Cellular Physiology (2019)
34. The Insulin-Like Growth Factor Binding Protein-3 and Its Death Receptor in Pancreatic Ductal Adenocarcinoma Poor Prognosis, Journal of Cellular Physiology (2019)
35. Effect of Hydatid Cyst Antigens on Inhibition of Melanoma Cancer Growth in Mouse Model, Cellular and Molecular Biology (2018)
36. Immobilization of Lactoperoxidase on Graphene Oxide Nanosheets With Improved Activity and Stability, Biotechnology Letters (2018)
37. In Silico Interaction of Insulin-Like Growth Factor Binding Protein 3 With Insulin-Like Growth Factor 1, Research in Pharmaceutical Sciences (2018)
38. Serum-Based Microrna Biomarkers for Major Depression: Mir-16, Mir-135A, and Mir-1202, Journal of Research in Medical Sciences (2018)
39. Studies on the Kinetics of Antibacterial Agent Production in Two Actinomycete Strains, F9 and Is5, Isolated From Soil Samples, Iran, Iranian Journal of Science and Technology, Transaction A: Science (2018)
40. Bench-Scale Overproduction and Purification of Recombinant Gcsf in Escherichia Coli Fed-Batch Process, Journal of Applied Pharmaceutical Science (2017)
41. Excellent Biofouling Alleviation of Thermoexfoliated Vermiculite Blended Poly(Ether Sulfone) Ultrafiltration Membrane, ACS Applied Materials and Interfaces (2017)
42. Recombinant Production, Purification and Characterization of Vessel Dilator in E. Coli, Protein Expression and Purification (2017)
43. The Interaction of Insulin-Like Growth Factor Binding Protein 3 (Igfbp-3) in Insulin-Like Growth Factor (Igf)-Independent System, Journal of Isfahan Medical School (2017)
44. Efficient Process Development of Recombinant Human Granulocyte Colony-Stimulating Factor (Rh-Gcsf) Production in Escherichia Coli, Iranian Biomedical Journal (2015)
45. Enhanced Production of Insulin-Like Growth Factor I Protein in Escherichia Coli by Optimization of Five Key Factors, Iranian Journal of Pharmaceutical Research (2015)
46. The Effect of Cell Disruption Techniques and Chaotropic Agents on the Downstream Purification Process of Mecasermin Produced As Inclusion Body in E. Coli, Research in Pharmaceutical Sciences (2015)
47. Cloning and Expression of Epidermal Lipoxygenase From Ambystoma Mexicanum (Loxe) in Escherichia Coli, Journal of Isfahan Medical School (2014)
48. High Overexpression and Purification of Optimized Bacterio-Opsin From Halobacterium Salinarum R1 in E. Coli, Applied Biochemistry and Biotechnology (2014)
49. Recombinant Production of Mecasermin in E. Coli Expression System, Research in Pharmaceutical Sciences (2014)
50. The Antimicrobial Effects and Metabolomic Footprinting of Carboxyl-Capped Bismuth Nanoparticles Against Helicobacter Pylori, Applied Biochemistry and Biotechnology (2014)
51. Anti-Oxidative and Anti-Inflammatory Effects of Ginger in Health and Physical Activity: Review of Current Evidence, International Journal of Preventive Medicine (2013)
52. Expression and Purification of Pfu Dna Polymerase Belonging to the B Family Polymerase, Journal of Isfahan Medical School (2013)
53. Molecular Cloning and Characterization of the Phenylalanine Aminomutase Gene From Taxus Baccata L, Iranian Journal of Biotechnology (2013)
54. The Effect and Mechanism of Action of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 in Human Breast Cancer; a Systematic Review, Journal of Isfahan Medical School (2013)
55. Biosynthesis of Bismuth Nanoparticles Using Serratia Marcescens Isolated From the Caspian Sea and Their Characterisation, IET Nanobiotechnology (2012)
56. Enhanced Taxane Production and Secretion From Taxus Baccata Cell Culture by Adding Dimethylsulfoxide, Biotechnology and Applied Biochemistry (2012)
57. Heterologous Virus-Induced Gene Silencing As a Promising Approach in Plant Functional Genomics, Molecular Biology Reports (2012)
58. Ligation Independent Cloning of Polycistronic, Genetically Modified, Humab4d5-8 F (Ab') 2, in Bacterial Plasmid, Avicenna Journal of Medical Biotechnology (2012)
59. Optimization of the Basal Medium for Improving Production and Secretion of Taxanes From Suspension Cell Culture of Taxus Baccata L, DARU, Journal of Pharmaceutical Sciences (2012)
60. Comparison of Epothilone and Taxol Binding in Yeast Tubulin Using Molecular Modeling, Avicenna Journal of Medical Biotechnology (2011)
61. Rapid Germination and Development of Taxus Baccata L. by in Vitro Embryo Culture and Hydroponic Growth of Seedlings, In Vitro Cellular and Developmental Biology - Plant (2011)
62. Creation of Tenecteplase-Producing Cho Cell Line Using Site-Specific Integrase From the Phage Φc31, Yakhteh (2010)
63. Investigation of a Medicinal and Ornamental Plant Propagation, the Cereus Peruvianus Mill. and Using Tissue Culture Technique, Journal of Medicinal Plants (2010)
64. Quantification of Ergovaline Using Hplc and Mass Spectrometry in Iranian Neotyphodium Infected Tall Fescue, Research in Pharmaceutical Sciences (2010)