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Clinical Trials, Patents, and Marketed Products of Nanocurcumin-Based Anticancer Drug Delivery Systems Publisher



Hassanizadeh S1 ; Askari G1, 2 ; Kesharwani P3 ; Bagherniya M1, 2 ; Sahebkar A4, 5
Authors
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Authors Affiliations
  1. 1. Nutrition and Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Anesthesia and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India
  4. 4. Applied Biomedical Research Center, Mashhad University Of Medical Sciences, Mashhad, Iran
  5. 5. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University Of Medical Sciences, Mashhad, Iran

Source: Curcumin-Based Nanomedicines as Cancer Therapeutics Published:2024


Abstract

Globally, cancer is a disease that seriously impacts the population. Successful treatment and prevention of this life-threatening disease require new treatment methods. Recently, research has focused on natural compounds and development of more efficient drug delivery systems. Curcumin is a natural compound with antitumor, antioxidant, and antiinflammatory properties. However, it has low bioavailability in aquatic environments. To improve the bioavailability of curcumin and its anticancer properties, researchers have used nanocurcumin. There are dietary supplements, herbal medicines, and food additives containing nanocurcumin available worldwide. A good safety profile has been reported for these products. A summary of recent human clinical trials that have evaluated nanocurcumin's anticancer activity is presented in this chapter, as well as a review of patents, marketed nanocurcumin products, and various nanocurcumin delivery systems. © 2024 Elsevier Inc. All rights are reserved including those for text and data mining AI training and similar technologies.
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