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Biomedical Applications of Superparamagnetic Nanoparticles in Molecular Scale Publisher



Rahman M1 ; Saei AA2, 3, 4 ; Amiri H5, 6 ; Mahmoudi M3, 7
Authors
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Authors Affiliations
  1. 1. Department of Chemical Engineering and Materials Science, University of California Davis, United States
  2. 2. Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Nanotechnology, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
  5. 5. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
  6. 6. Department of Radiology, Radboud University Medical Center, Nijmegen, Netherlands
  7. 7. Division of Cardiovascular Medicine, Stanford University (School of Medicine), Stanford, United States

Source: Current Organic Chemistry Published:2015


Abstract

Magnetic nanoparticles and especially superparamagnetic iron oxide nanoparticles (SPIONs) have found innumerable applications in bioscience and biotechnology. Accommodation of active molecules and forming homogeneous dispersion in solution, combined with easy capture by external magnetic fields has made them favorable candidates for molecular scale applications such as sensing and detection, imaging, targeted delivery, toxin decorporation, catalysis and pathogen removal. This review summarizes the recent advances and challenges in the above-mentioned applications. © 2015 Bentham Science Publishers.
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