Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Prevalence and Resistance Patterns of Uropathogens in Critically Ill Patients at a Tertiary Care Hospital in Tehran: Implications for Antimicrobial Stewardship in Developing Countries
Mojtaba Mojtahedzadeh
Mojtaba Mojtahedzadeh

Professor of Critical Care Pharmarcotherapy

Department Clinical Pharmacy

School of Pharmacy

Sina Hospital

Medicinal Plants Research Center

Tehran University of Medical Sciences

All Documents
1. Beyond the Walls of the Icu: A Story of Survival, Family Resilience, and Silent Struggles-Editorial, Archives of Anesthesiology and Critical Care (2025)
2. Can the Neuroprotective Effects of Memantine Prevent the Complications of Brain Injuries? a Systematic Review of Animal Models, Brain Injury (2025)
3. Clinical Evaluation of Umifenovir As a Potential Antiviral Therapy for Covid-19: A Multi-Center, Randomized, Controlled Clinical Trial, Oman Medical Journal (2025)
4. Clinical Investigation of Protective Effects of Melatonin on Patients With Acute Ischemic Stroke, Archives of Anesthesiology and Critical Care (2025)
5. Investigating the Agreement of Hypomagnesemia Diagnosis in Three Perimeter of Serum, Urine, and Red Blood Cell in Intensive Care Unit: Pilot Study, Archives of Anesthesiology and Critical Care (2025)
6. Massive Gastrointestinal Bleeding, Consequences Interactions of Apixaban, Diltiazem and Aspirin: Case Report, Archives of Anesthesiology and Critical Care (2025)
7. Perioperative Use of Pregabalin Vs. Duloxetine for Pain Management of Knee Fracture Surgery: A Double-Blind Randomized Clinical Trial, Iranian Journal of Pharmaceutical Research (2025)
8. Predictors of Mortality for Severe Covid-19: A Descriptive Analysis From an Intensive Care Unit of a Tertiary Care Center, Archives of Anesthesiology and Critical Care (2025)
9. Prevalence and Resistance Patterns of Uropathogens in Critically Ill Patients at a Tertiary Care Hospital in Tehran: Implications for Antimicrobial Stewardship in Developing Countries, Microbial Drug Resistance (2025)
10. Renal Impact of a High-Loading Dose of Amikacin in Critically Ill Patients, Pharmaceutical Sciences (2025)
11. Sepsis Management in a Case of Myasthenic Crisis: A Case Report, Archives of Anesthesiology and Critical Care (2025)
12. The Effectiveness of Unfractionated Heparin Vs. Low Molecular Weight (Enoxaparin) in Acute Respiratory Distress Syndrom (Ards) and Metabolic Dysfunction: An Old Drug for New Indication!, BMC Immunology (2025)
13. Warfarin Without Therapeutic Monitoring Is a Rodenticide, But This Time It Kills the Patient: A Warfarin Toxicity Case Report, Archives of Anesthesiology and Critical Care (2025)
14. 6-Gingerol Anti-Inflammatory and Antioxidant Properties Protect Against Heart and Liver Dysfunction in Rats With Sepsis, Pharmacological Research - Modern Chinese Medicine (2024)
15. Effects of Hypertonic Sodium Lactate on Intracranial Pressure in Patients With Traumatic Brain Injury: A Systematic Review and Meta-Analysis on Clinical Trial Studies, Basic and Clinical Neuroscience (2024)
16. Enhancing Analgesia in Acute Renal Colic Pain: A Randomized Controlled Trial of Gabapentin Adjunct to Ketorolac-Based Regimen, Frontiers in Pain Research (2024)
17. Familial Hypokalemic Periodic Paralysis Attack Following Sars- Cov- 2 Infection: A Case Report, Archives of Anesthesiology and Critical Care (2024)
18. High Dose of Vitamin C in Septic and Critically Ill Patients With Covid-19: A Narrative Review, Journal of Nutrition and Food Security (2024)
19. Intragastric Botulinum Toxin Injection and Botulism: An Alarm for Clinicians, Case Reports in Critical Care (2024)
20. Oral Regimen for High Dose Methotrexate Urine Alkalinization: A Systematic Review and Meta-Analysis, DARU# Journal of Pharmaceutical Sciences (2024)
21. Successful Treatment of Pulmonary Embolism Causing Cardiac Arrests With Reteplase During Neurosurgery: A Case Report, Archives of Anesthesiology and Critical Care (2024)
22. 3D Self-Assembled Nanocarriers for Drug Delivery, Drug Metabolism Reviews (2023)
23. Correlation of Biofilm Formation, Virulence Factors, and Phylogenetic Groups Among Escherichia Coli Strains Causing Urinary Tract Infection: A Global Systematic Review and Meta‑Analysis, Journal of Research in Medical Sciences (2023)
24. Effect of Famotidine on Covid-19: Killing Virus or Opposing Ards?, Pulmonary Therapy (2023)
25. Effect of Vitamin C on Coagulation Factors and Endothe-Lium Function in Patients With Sepsis, Frontiers in Emergency Medicine (2023)
26. Limonene, Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 (2023)
27. Metabolic Modeling-Based Drug Repurposing in Statin: An Overview of Mechanistic Approaches in the Management of Craniocerebral Trauma, Journal of Cellular and Molecular Anesthesia (2023)
28. A Repurposed Drug Screen for Regulating Metabolic Disease: An Overview in the Management of Traumatic Brain Injury; [Una Deteccion De Drogas Reutilizada Para Regular La Enfermedad Metabolica: Una Descripcion General En El Manejo De La Lesion Cerebral Traumatica], Revista Latinoamericana de Hipertension (2022)
29. Adopting Clinical Practice Guidelines for Pharmacologic Managementofacutespinalcordinjuryfromadeveloped World Context to a Developing Global Region, Archives of Iranian Medicine (2022)
30. Can Intra-Abdominal Pressure Predict the Pharmacokinetics of Aminoglycosides in Critically Ill Patients With Intra-Abdominal Sepsis?, American Journal of Therapeutics (2022)
31. Efficacy of Glucocorticoid Administration in Patients With Cardiac Arrest: A Systematic Review of Clinical Studies, Current Medicinal Chemistry (2022)
32. Efficacy of Lacosamide in the Treatment of Non-Convulsive Seizure and Non-Convulsive Status Epilepticus in Septic Pa-Tients: A Narrative Review, Frontiers in Emergency Medicine (2022)
33. Evaluation of Amikacin Dosing Schedule in Critically Ill Elderly Patients With Different Stages of Renal Dysfunction, European Journal of Hospital Pharmacy (2022)
34. Evaluation of Intravenous Phenobarbital Pharmacokinetics in Critically Ill Patients With Brain Injury, Acta Medica Iranica (2022)
35. Management of a Critically Ill Patient With Covid-19-Related Fulminant Myocarditis: A Case Report, Respiratory Medicine Case Reports (2022)
36. Pharmacokinetic Study of High-Dose Oral Rifampicin in Critically Ill Patients With Multidrug-Resistant Acinetobacter Baumannii Infection, DARU# Journal of Pharmaceutical Sciences (2022)
37. Pharmacologic Therapies of Pain in Patients With Spinal Cord Injury: A Systematic Review, Spinal Cord Series and Cases (2022)
38. Predictors of Mortality Among Covid-19 Patients Admitted to Intensive Care Units: A Single-Center Study in Tehran, Iran, Archives of Iranian Medicine (2022)
39. Recent Trends and Innovations in Biosensors Development for Biomarkers Towards Monitoring Traumatic Brain Injury, Biosensors and Bioelectronics: X (2022)
40. Relationship Between Amikacin Pharmacokinetics and Biological Parameters Associated With Organ Dysfunction: A Case Series Study of Critically Ill Patients With Intra-Abdominal Sepsis, European Journal of Hospital Pharmacy (2022)
41. Remdesivir Administration in Covid-19 Patients With Renal Impairment: A Systematic Review, American Journal of Therapeutics (2022)
42. The First Report of Bacteroides Fragilis and Bacteroides Thetaiotaomicron Relative Abundance in Obese Iranian Population, Jundishapur Journal of Natural Pharmaceutical Products (2022)
43. Ultrasonic Cardiac Output Monitoring in Intubated Patients With and Without Covid-19 in the Icu: A Prospective Cohort Study, Frontiers in Emergency Medicine (2022)
44. Antibiotic Therapy in Sepsis: No Next Time for a Second Chance!, Journal of Clinical Pharmacy and Therapeutics (2021)
45. Bowel Obstruction Caused by Persimmon Phytobezoars: A Case Report, International Journal of Medical Toxicology and Forensic Medicine (2021)
46. Clinical Effectiveness of a High Dose Versus the Standard Dose of Meropenem in Ventilator-Associated Pneumonia Caused by Multidrug-Resistant Bacteria: A Randomized, Single-Blind Clinical Trial, Infectious Disorders - Drug Targets (2021)
47. Effect of Heart Rate Control With Amiodarone Infusion on Hemodynamic and Clinical Outcomes in Septic Shock Patients With Tachycardia: A Prospective, Single-Arm Clinical Study, Journal of Pharmaceutical Health Care and Sciences (2021)
48. Efficacy and Safety of Different Dosage of Recombinant Tissue-Type Plasminogen Activator (Rt-Pa) in the Treatment of Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis, Iranian Journal of Pharmaceutical Research (2021)
49. Evaluating the Neuroprotective Effect of Melatonin on Patients With Hemorrhagic Stroke Using Serum S100b Protein As a Prognostic Marker, Jundishapur Journal of Natural Pharmaceutical Products (2021)
50. Evaluating the Neuroprotective Effect of Melatonin on Patients With Hemorrhagic Stroke Using Serum S100b Protein As a Prognostic Marker, Jundishapur Journal of Natural Pharmaceutical Products (2021)
51. Evaluation of the Effects of Melatonin Supplementation on Coagulation in Patients With Haemorrhagic Stroke; a Randomized, Double-Blind, Controlled Trial, Frontiers in Emergency Medicine (2021)
52. Possible Role of Selective Serotonin Reuptake Inhibitors (Ssris) in Clinical Outcome of Covid-19 Patients, Frontiers in Emergency Medicine (2021)
53. Protective Effects of Intravenous Magnesium Sulfate in Stroke Patients Receiving Amiodarone: A Randomized Controlled Trial, Advances in Experimental Medicine and Biology (2021)
54. Short-Term Effects of Metformin on Cardiac and Peripheral Blood Cells Following Cecal Ligation and Puncture-Induced Sepsis, Drug Research (2021)
55. Systematic Review: Effectiveness of Herbal Oral Care Products on Ventilator-Associated Pneumonia, Phytotherapy Research (2021)
56. A Perspective on Erythropoietin As a Potential Adjuvant Therapy for Acute Lung Injury/Acute Respiratory Distress Syndrome in Patients With Covid-19, Archives of Medical Research (2020)
57. A Review on the Protective Effects of Metformin in Sepsis-Induced Organ Failure, Cell Journal (2020)
58. Area Under the Curve-Based Dosing of Vancomycin in Critically Ill Patients Using 6-Hour Urine Creatinine Clearance Measurement, Critical Care Research and Practice (2020)
59. Evaluation of Amikacin Pharmacokinetics in Critically Ill Patients With Intra-Abdominal Sepsis, Advanced Pharmaceutical Bulletin (2020)
60. Evaluation of Epithelial Lining Fluid Concentration of Amikacin in Critically Ill Patients With Ventilator-Associated Pneumonia, Journal of Intensive Care Medicine (2020)
61. Evaluation of Neuroprtective Effects of L-Carnitine and Fat Emulsion in the Cva Patients: A Prospective, Randomized, Double Blind, Clinical Trial, Iranian Journal of Pharmaceutical Research (2020)
62. Extraction and Evaluation of Outer Membrane Vesicles From Two Important Gut Microbiota Members, Bacteroides Fragilis and Bacteroides Thetaiotaomicron, Cell Journal (2020)
63. Metformin Attenuates Brain Injury by Inhibiting Inflammation and Regulating Tight Junction Proteins in Septic Rats, Cell Journal (2020)
64. Pharmacological Treatments of Covid-19, Pharmacological Reports (2020)
65. A Cost-Effectiveness Analysis of Albumin in Septic Shock: A Patient-Level Data Analysis, Clinical Therapeutics (2019)
66. A Randomized Controlled Trial on the Efficacy, Safety, and Pharmacokinetics of Metformin in Severe Traumatic Brain Injury, Journal of Neurology (2019)
67. Is Albumin-Based Resuscitation in Severe Sepsis and Septic Shock Justifiable? an Evidence From a Cost-Effectiveness Evaluation, Ethiopian journal of health sciences (2019)
68. Management of Hypotension and Bradycardia Caused by Spinal Cord Injury. the Usefulness of Midodrine and Methylxanthines, Iranian Journal of Pharmaceutical Research (2019)
69. Response to Letter to the Editor: Fluid Volume, Fluid Balance and Patient Outcome in Severe Sepsis and Septic Shock: A Systematic Review, Journal of Critical Care (2019)
70. Adaptation of the Pharmacological Management of Delirium in Icu Patients in Iran: Introduction and Definition, Iranian Journal of Psychiatry (2018)
71. Analgesic and Sedative Agents Used in the Intensive Care Unit: A Review, Journal of Cellular Biochemistry (2018)
72. Cotreatment With Furosemide and Hypertonic Saline Decreases Serum Neutrophil Gelatinase-Associated Lipocalin (Ngal) and Serum Creatinine Concentrations in Traumatic Brain Injury: A Randomized, Single-Blind Clinical Trial, Iranian Journal of Pharmaceutical Research (2018)
73. Differentiating the Effects of Prophylactic Unfractionated Heparin Infusion by Rotational Thromboelastometry in Sepsis, Point of Care (2018)
74. Fluid Volume, Fluid Balance and Patient Outcome in Severe Sepsis and Septic Shock: A Systematic Review, Journal of Critical Care (2018)
75. High-Dose Amikacin for Achieving Serum Target Levels in Critically Ill Elderly Patients, Infection and Drug Resistance (2018)
76. Monomethyl Fumarate Alleviates Sepsis-Induced Hepatic Dysfunction by Regulating Tlr-4/Nf-Κb Signalling Pathway, Life Sciences (2018)
77. Neuroprotective Agents in the Intensive Care Unit, Journal of Pharmacopuncture (2018)
78. Prevalence of Candidemia and Associated Candida Subtypes Following Severe Sepsis in Non-Neutropenic Critically Ill Patients, Acta Biomedica (2018)
79. Randomized Trial of Carnitine for the Prevention of Perioperative Atrial Fibrillation, Seminars in Thoracic and Cardiovascular Surgery (2018)
80. The Role of Epigenetic Alterations Involved in Sepsis: An Overview, Current Pharmaceutical Design (2018)
81. Therapeutic Effects of Oral Liothyronine on Aluminum Phosphide Poisoning As an Adjuvant Therapy: A Clinical Trial, Human and Experimental Toxicology (2018)
82. Effect of Calories Delivered on Clinical Outcomes in Critically Ill Patients: Systemic Review and Meta-Analysis, Indian Journal of Critical Care Medicine (2017)
83. Effect of Hypertonic Saline 5% on Early Graft Function and Urinary Interleukin 18 and Neutrophil Gelatinase-Associated Lipocalin in Deceased-Donor Kidney Transplantation, Iranian Journal of Pharmaceutical Research (2017)
84. The Effect of High-Dose Parenteral Sodium Selenite in Critically Ill Patients Following Sepsis: A Clinical and Mechanistic Study, Indian Journal of Critical Care Medicine (2017)
85. The Effect of Osmotherapy and Tight Control of Acidosis on Early Graft Function Among Deceased- Donor Kidney Transplant Recipients: A Randomized Controlled Trial, International Journal of Organ Transplantation Medicine (2017)
86. The Role of Magnesium Sulfate in the Intensive Care Unit, EXCLI Journal (2017)
87. Vasopressin in Septic Shock; Assessment of Sepsis Biomarkers: A Randomized, Controlled Trial, Indian Journal of Critical Care Medicine (2017)
88. Vasopressin in Septic Shock; Assessment of Sepsis Biomarkers: A Randomized, Controlled Trial, Indian Journal of Critical Care Medicine (2017)
89. Achievement of Vancomycin Therapeutic Goals in Critically Ill Patients: Early Individualization May Be Beneficial, Critical Care Research and Practice (2016)
90. Achievement of Vancomycin Therapeutic Goals in Critically Ill Patients: Early Individualization May Be Beneficial, Critical Care Research and Practice (2016)
91. Analgesic Efficacy of Nephrostomy Tract Infiltration of Bupivacaine and Ketamine After Tubeless Percutaneous Nephrolithotomy: A Prospective Randomized Trial, Iranian Journal of Pharmaceutical Research (2016)
92. Comparison of the Effects of Subcutaneous Versus Continuous Infusion of Heparin on Key Inflammatory Parameters Following Sepsis, Anesthesiology and Pain Medicine (2016)
93. Predictive Values of Urinary Interleukin 18 and Neutrophil Gelatinase-Associated Lipocalin for Delayed Graft Function Diagnosis in Kidney Transplantation, Iranian Journal of Pathology (2016)
94. Randomized Trial of the Effect of Magnesium Sulfate Continuous Infusion on Il-6 and Crp Serum Levels Following Abdominal Aortic Aneurysm Surgery, Iranian Journal of Pharmaceutical Research (2016)
95. The Therapeutic Role of Vasopressin on Improving Lactate Clearance During and After Vasogenic Shock: Microcirculation, Is It the Black Box?, Acta Medica Iranica (2016)
96. The Therapeutic Role of Vasopressin on Improving Lactate Clearance During and After Vasogenic Shock: Microcirculation, Is It the Black Box?, Acta Medica Iranica (2016)
97. Early Goal-Directed Therapy Reduces Mortality in Adult Patients With Severe Sepsis and Septic Shock: Systematic Review and Meta-Analysis, Indian Journal of Critical Care Medicine (2015)
98. Effect of Magnesium on Functional Outcome and Paraclinical Parameters of Patients Undergoing Supratentorial Craniotomy for Brain Tumors: A Randomized Controlled Trial, Acta Neurochirurgica (2015)
99. Immunomodulatory Effect of Hypertonic Saline in Hemorrhagic Shock, DARU# Journal of Pharmaceutical Sciences (2015)
100. Potential Effect of L-Carnitine on the Prevention of Myocardial Injury After Coronary Artery Bypass Graft Surgery, Journal of Tehran University Heart Center (2015)
101. The Effect of Curcumin on Some of Traditional and Non-Traditional Cardiovascular Risk Factors: A Pilot Randomized, Double-Blind, Placebo-Controlled Trial, Iranian Journal of Pharmaceutical Research (2015)
102. The Effect of Parenteral Selenium on Outcomes of Mechanically Ventilated Patients Following Sepsis: A Prospective Randomized Clinical Trial, Annals of Intensive Care (2015)
103. Towards Future Indications of Therapeutic Utilization of Stem Cells: A Case Report of Application After Hypoxic Encephalopathy, Iranian Journal of Public Health (2015)
104. Comparison of the Effects of Enoxaparin and Heparin on Inflammatory Biomarkers in Patients With St-Segment Elevated Myocardial Infarction: A Prospective Open Label Pilot Clinical Trial, Iranian Journal of Pharmaceutical Research (2014)
105. Reliability of Calcium-Binding Protein S100b Measurement Toward Optimization of Hyperosmolal Therapy in Traumatic Brain Injury, European Review for Medical and Pharmacological Sciences (2013)
106. Risk Factors and Prognostic Factors of Acute Renal Failure in Patients Admitted to an Intensive Care Unit, Tehran-Iran, Iranian Journal of Pharmacology and Therapeutics (2009)