Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Design and Optimization of Plga-Based Tribulus Terrestris Loaded Nanoparticles
Farid Dorkoosh
Farid Dorkoosh

Professor of Pharmaceutics

Department Pharmaceutics

School of Pharmacy

Tehran University of Medical Sciences

Related Documents
1. Investigation of Effective Parameters on Size of Paclitaxel Loaded Plga Nanoparticles, Advanced Pharmaceutical Bulletin (2018)
All Documents
1. A Novel Controlled Release Implant of Insulin Based on Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Polymer Prepared by Extrusion, Turkish Journal of Pharmaceutical Sciences (2024)
2. Antibacterial Activity of a Silver-Incorporated Vancomycin-Modified Mesoporous Silica Against Methicillin-Resistant Staphylococcus Aureus, Journal of Biomaterials Applications (2024)
3. Development, Optimization, and Characterization of Vitamin C-Fortified Oleogel-Based Chewable Gels and a Novel Nondestructive Analysis Method for the Vitamin C Assay, Food Production, Processing and Nutrition (2024)
4. Hierarchical Porous Bio Polyurethane Film As an Implantable Delivery System for Sustained Release of Insulin: Synthesis, Characterization, and In-Vitro Evaluation, Reactive and Functional Polymers (2024)
5. Preparation, Characterization and in Vitro Evaluation of Insulin-Phbv Nanoparticles/Alginate Hydrogel Composite System for Prolonged Delivery of Insulin, Journal of Pharmaceutical Sciences (2024)
6. Review of Recent Preclinical and Clinical Research on Ligand-Targeted Liposomes As Delivery Systems in Triple Negative Breast Cancer Therapy, Journal of Liposome Research (2024)
7. Co-Delivery of Paclitaxel and Regorafenib by F127/Tpgs Mixed Micelles for Triple Negative Breast Cancer Treatment, Journal of Drug Delivery Science and Technology (2023)
8. Nanomedicine “New Food for an Old Mouth”: Novel Approaches for the Treatment of Covid-19, Drug Delivery Letters (2023)
9. Targeted Delivery of Anticancer Drug Loaded Charged Plga Polymeric Nanoparticles Using Electrostatic Field, Macromolecular Bioscience (2023)
10. The Influence of Polymer Type and Concentration on the Metoprolol Mass Transfer in Extended-Release Tablet of Metoprolol Succinate, Journal of Chemical and Petroleum Engineering (2023)
11. Uv Spectroscopy: A Novel Method for Determination of Degree of Substitution of Phthaloyl Group As Amine Protector in Chitosan, Zeitschrift fur Physikalische Chemie (2023)
12. Co-Delivery Systems: Hope for Clinical Application?, Drug Delivery and Translational Research (2022)
13. Electrospun Fibers: Versatile Approaches for Controlled Release Applications, International Journal of Polymer Science (2022)
14. In-Depth Multidisciplinary Review of the Usage, Manufacturing, Regulations & Market of Dietary Supplements, Journal of Drug Delivery Science and Technology (2022)
15. Magnetic Hydrogel for Cartilage Tissue Regeneration As Well As a Review on Advantages and Disadvantages of Different Cartilage Repair Strategies, BioMed Research International (2022)
16. Oral Delivery of Therapeutic Peptides and Proteins: Technology Landscape of Lipid-Based Nanocarriers, Advanced Drug Delivery Reviews (2022)
17. Telemedicine, Computer Aided Pharmaceutics and Drug Delivery: an Application Guide for Students and Researchers of Pharmaceutical Sciences (2022)
18. Theranostic Applications of Stimulus-Responsive Systems Based on Fe2 O3, Pharmaceutical Nanotechnology (2022)
19. A Novel Approach for Development of Intraocular Biodegradable Ranibizumab Implant: A Solution for Stability of Protein Activity, Advanced Pharmaceutical Bulletin (2021)
20. Application of Chloroquine As an Endosomal Escape Enhancing Agent: New Frontiers for an Old Drug, Expert Opinion on Drug Delivery (2021)
21. Cardiac Tissue Engineering, Biomaterial Scaffolds, and Their Fabrication Techniques, Polymers for Advanced Technologies (2021)
22. Chloroquine Assisted Delivery of Microrna Mimic Let-7B to Nsclc Cell Line by Pamam (G5)-Ha Nano-Carrier, Current Drug Delivery (2021)
23. Design and in Vitro Evaluation of a Slow-Release Intraocular Implant of Betamethasone, AAPS PharmSciTech (2021)
24. Effect of Oral Administration of Gnrha+Nanoparticles of Chitosan in Oogenesis Acceleration of Goldfish Carassius Auratus, Fish Physiology and Biochemistry (2021)
25. Nanobodies As Powerful Pulmonary Targeted Biotherapeutics Against Sars-Cov-2, Pharmaceutical Point of View, Biochimica et Biophysica Acta - General Subjects (2021)
26. Nanomedicine and Chemotherapeutics Drug Delivery: Challenges and Opportunities, Journal of Drug Targeting (2021)
27. Preparation and Pulsatile Release Evaluation of Teriparatide-Loaded Multilayer Implant Composed of Polyanhydride-Hydrogel Layers Using Spin Coating for the Treatment of Osteoporosis, Journal of Pharmaceutical Innovation (2021)
28. Preparation of Carbon Quantum Dots- Quinic Acid for Drug Delivery of Gemcitabine to Breast Cancer Cells, Journal of Drug Delivery Science and Technology (2021)
29. Publish or Perish: An Academic Status Anxiety, Pharmaceutical Nanotechnology (2021)
30. Star-Hyperbranched Waterborne Polyurethane Based on D-Glucose-Poly(Ε-Caprolactone) Core As a Biomaterial Candidate, European Polymer Journal (2021)
31. Adcs, As Novel Revolutionary Weapons for Providing a Step Forward in Targeted Therapy of Malignancies, Current Drug Delivery (2020)
32. Application of Chitosan in Oral Drug Delivery, Functional Chitosan: Drug Delivery and Biomedical Applications (2020)
33. Application of Nano-Based Systems for Drug Delivery and Targeting: A Review, Journal of Nanoparticle Research (2020)
34. Art and Drug Delivery System Design: Dissonance or a Harmony?, Expert Opinion on Drug Delivery (2020)
35. Chloroquine: A Brand-New Scenario for an Old Drug, Expert Opinion on Drug Delivery (2020)
36. Fabrication, Optimization, and in Vitro and in Vivo Characterization of Intra-Vitreal Implant of Budesonide Generally Made of Phbv, AAPS PharmSciTech (2020)
37. Improving the In-Vivo Biological Activity of Fingolimod Loaded Phbv Nanoparticles by Using Hydrophobically Modified Alginate, Drug Development and Industrial Pharmacy (2020)
38. K-Casein Upregulates Osteogenic Differentiation on Bone Marrow Mesenchymal Stem Cells Cultured on Agarose Microcarriers, International Journal of Polymeric Materials and Polymeric Biomaterials (2020)
39. Mitochondrial Delivery of Microrna Mimic Let-7B to Nsclc Cells by Pamam-Based Nanoparticles, Journal of Drug Targeting (2020)
40. Phbv/Plga Nanoparticles for Enhanced Delivery of 5-Fluorouracil As Promising Treatment of Colon Cancer, Pharmaceutical Development and Technology (2020)
41. Temperature-Responsive Methylcellulose-Hyaluronic Hydrogel As a 3D Cell Culture Matrix, Biomacromolecules (2020)
42. A Novel Method for the Simultaneous Determination of 5-Fluorouracil and Oxaliplatin in New Biodegradable Phbv/Plga Nanoparticles, Journal of the Iranian Chemical Society (2019)
43. An Experimental Investigation to the Thermal Conductivity Enhancement of Paraffin Wax As a Phase Change Material Using Diamond Nanoparticles As a Promoting Factor, Heat and Mass Transfer/Waerme- und Stoffuebertragung (2019)
44. Co-Delivery of 5-Fluorouracil and Oxaliplatin in Novel Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate Acid)/Poly(Lactic-Co-Glycolic Acid) Nanoparticles for Colon Cancer Therapy, International Journal of Biological Macromolecules (2019)
45. Comparison of 0.2% Chlorhexidine Mouthwash With and Without Anti-Discoloration System in Patients With Chronic Periodontitis: A Randomized Controlled Clinical Trial, Journal of Advanced Periodontology and Implant Dentistry (2019)
46. Development of Octreotide-Loaded Chitosan and Heparin Nanoparticles: Evaluation of Surface Modification Effect on Physicochemical Properties and Macrophage Uptake, Journal of Pharmaceutical Sciences (2019)
47. Fabrication of Long-Acting Insulin Formulation Based on Poly (3-Hydroxybutyrate-Co-3-Hydroxyvalerate) (Phbv) Nanoparticles: Preparation, Optimization, Characterization, and in Vitro Evaluation, Pharmaceutical Development and Technology (2019)
48. New Folate Receptor Targeted Nano Liposomes for Delivery of 5-Fluorouracil to Cancer Cells: Strong Implication for Enhanced Potency and Safety, Life Sciences (2019)
49. Pegylated Magnetic Mesoporous Silica Nanoparticles Decorated With As1411 Aptamer As a Targeting Delivery System for Cytotoxic Agents, Pharmaceutical Development and Technology (2019)
50. Preparation of Curcumin-Loaded Plga Nanoparticles and Investigation of Its Cytotoxicity Effects on Human Glioblastoma U87mg Cells, Biointerface Research in Applied Chemistry (2019)
51. Sustained Delivery of Olanzapine From Sunflower Oil-Based Polyol-Urethane Nanoparticles Synthesised Through a Cyclic Carbonate Ring-Opening Reaction, IET Nanobiotechnology (2019)
52. A Mechanistic Study of the Effect of Transferrin Conjugation on Cytotoxicity of Targeted Liposomes, Journal of Microencapsulation (2018)
53. A Novel 5-Fluorouracil Targeted Delivery to Colon Cancer Using Folic Acid Conjugated Liposomes, Biomedicine and Pharmacotherapy (2018)
54. Cellulose Acetate Electrospun Nanofibers for Drug Delivery Systems: Applications and Recent Advances, Carbohydrate Polymers (2018)
55. Development and Characterization of Electrosprayed Nanoparticles for Encapsulation of Curcumin, Journal of Biomedical Materials Research - Part A (2018)
56. Effects of Coating Layer and Release Medium on Release Profile From Coated Capsules With Eudragit Fs 30D: An in Vitro and in Vivo Study, Drug Development and Industrial Pharmacy (2018)
57. Folic Acid-Modified Liposomal Drug Delivery Strategy for Tumor Targeting of 5-Fluorouracil, European Journal of Pharmaceutical Sciences (2018)
58. In Vitro and in Vivo Evaluation of Coated Capsules for Colonic Delivery, Journal of Drug Delivery Science and Technology (2018)
59. In-Vitro and In-Vivo Cytotoxicity and Efficacy Evaluation of Novel Glycyl-Glycine and Alanyl-Alanine Conjugates of Chitosan and Trimethyl Chitosan Nano-Particles As Carriers for Oral Insulin Delivery, International Journal of Pharmaceutics (2018)
60. Investigation of Effective Parameters on Size of Paclitaxel Loaded Plga Nanoparticles, Advanced Pharmaceutical Bulletin (2018)
61. In Vivo Evaluation of Ph and Time-Dependent Polymers As Coating Agent for Colonic Delivery Using Central Composite Design, Journal of Drug Delivery Science and Technology (2018)
62. Lipid-Based Nanoparticles for Drug Delivery Systems, Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery (2018)
63. Nanoparticles Prepared From N,N-Dimethyl-N-Octyl Chitosan As the Novel Approach for Oral Delivery of Insulin: Preparation, Statistical Optimization and In-Vitro Characterization, Iranian Journal of Pharmaceutical Research (2018)
64. Ocular Implant Containing Bevacizumab-Loaded Chitosan Nanoparticles Intended for Choroidal Neovascularization Treatment, Journal of Biomedical Materials Research - Part A (2018)
65. Preparation, Evaluation and Optimization of Nanoparticles Composed of Thiolated Triethyl Chitosan: A Potential Approach for Buccal Delivery of Insulin, Journal of Drug Delivery Science and Technology (2018)
66. Preparation, Statistical Optimization and in Vitro Evaluation of Pramipexole Prolonged Delivery System Based on Poly (3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Nanoparticles, Journal of Drug Delivery Science and Technology (2018)
67. Prolonged Injectable Formulation of Nafarelin Using in Situ Gel Combination Delivery System, Pharmaceutical Development and Technology (2018)
68. Synthesis and Characterization of a Novel Peptide-Grafted Cs and Evaluation of Its Nanoparticles for the Oral Delivery of Insulin, in Vitro, and in Vivo Study, International Journal of Nanomedicine (2018)
69. Transferrin Targeted Liposomal 5-Fluorouracil Induced Apoptosis Via Mitochondria Signaling Pathway in Cancer Cells, Life Sciences (2018)
70. A Novel Nanoemulsion-Based Method to Produce Ultrasmall, Water-Dispersible Nanoparticles From Chitosan, Surface Modified With Cell-Penetrating Peptide for Oral Delivery of Proteins and Peptides, International Journal of Nanomedicine (2017)
71. An Estimation of the Potential Utilization in Iranian Pharmaceutical Industry Involved in the Stock Exchange, 2008-2012, Iranian Journal of Pharmaceutical Research (2017)
72. Application of Artificial Neural Networks in the Design and Optimization of a Nanoparticulate Fingolimod Delivery System Based on Biodegradable Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate), Journal of Pharmaceutical Sciences (2017)
73. Efficient Gene Delivery to Primary Human Retinal Pigment Epithelial Cells: The Innate and Acquired Properties of Vectors, International Journal of Pharmaceutics (2017)
74. Encapsulation of Eptifibatide in Rgd-Modified Nanoliposomes Improves Platelet Aggregation Inhibitory Activity, Journal of Thrombosis and Thrombolysis (2017)
75. In Vitro and in Vivo Evaluation of Paclitaxel–Lapatinib-Loaded F127 Pluronic Micelles, Drug Development and Industrial Pharmacy (2017)
76. Liposome-Targeted Delivery for Highly Potent Drugs, Artificial Cells# Nanomedicine and Biotechnology (2017)
77. Nanoparticulate Fingolimod Delivery System Based on Biodegradable Poly (3-Hydroxybutyrate-Co-3-Hydroxyvalerate) (Phbv): Design, Optimization, Characterization and In-Vitro Evaluation, Pharmaceutical Development and Technology (2017)
78. Preparation of Mesalamine Nanoparticles Using a Novel Polyurethane-Chitosan Graft Copolymer, Pharmaceutical Nanotechnology (2017)
79. Preparation, Characterization and in Vivo Evaluation of a Combination Delivery System Based on Hyaluronic Acid/Jeffamine Hydrogel Loaded With Phbv/Plga Blend Nanoparticles for Prolonged Delivery of Teriparatide, European Journal of Pharmaceutical Sciences (2017)
80. Preparation, Characterization, and Optimization of Folic Acid-Chitosan-Methotrexate Core-Shell Nanoparticles by Box-Behnken Design for Tumor-Targeted Drug Delivery, AAPS PharmSciTech (2017)
81. Preparation, Optimization and Physicochemical Characterization of Aripiprazole Loaded Nano-Porous in Situ Forming Implant, Pharmaceutical Nanotechnology (2017)
82. Survival Improvement in Human Retinal Pigment Epithelial Cells Via Fas Receptor Targeting by Mir-374A, Journal of Cellular Biochemistry (2017)
83. The Synthesis of Tamoxifen-Loaded Albumin Nanoparticles by Homogenizers: Optimization and In Vitro Characterization, Journal of Drug Delivery Science and Technology (2017)
84. Design and Characterization of Mesalamine Loaded Nanoparticles for Controlled Delivery System, Nanomedicine Research Journal (2016)
85. Development and Validation of a Rapid Rp-Hplc-Dad Analysis Method for the Simultaneous Quantitation of Paclitaxel and Lapatinib in a Polymeric Micelle Formulation, Scientia Pharmaceutica (2016)
86. Development of Molecularly Imprinted Olanzapine Nano-Particles: In Vitro Characterization and in Vivo Evaluation, AAPS PharmSciTech (2016)
87. Health-Related Quality of Life and Health Utility Values in Beta Thalassemia Major Patients Receiving Different Types of Iron Chelators in Iran, International Journal of Hematology-Oncology and Stem Cell Research (2016)
88. Hyaluronic Acid-Coated Liposomes for Targeted Delivery of Paclitaxel, In-Vitro Characterization and In-Vivo Evaluation, Journal of Controlled Release (2016)
89. Liposomal Formulation for Co-Delivery of Paclitaxel and Lapatinib, Preparation, Characterization and Optimization, Journal of Liposome Research (2016)
90. Mesoporous Silica Nanoparticles Functionalized With Folic Acid/Methionine for Active Targeted Delivery of Docetaxel, OncoTargets and Therapy (2016)
91. Novel Ph-Responsive Multilayer Magnetic Nanoparticles for Controlled Drug Delivery, Journal of the Iranian Chemical Society (2016)
92. Optimization of Rgd-Modified Nano-Liposomes Encapsulating Eptifibatide, Iranian Journal of Biotechnology (2016)
93. Pluronic Based Nano-Delivery Systems; Prospective Warrior in War Against Cancer, Nanomedicine Research Journal (2016)
94. Preparation and Bioavailability Analysis of Ferrous Bis Alanine Chelate As a New Micronutrient for Treatment of Iron Deficiency Anemia, Advanced Pharmaceutical Bulletin (2016)
95. Preparation and Characterization of Nanoparticles Composed of Methylated N-(4-N,N-Dimethyl Aminobenzyl) Chitosan for Oral Delivery of Cyclosporine A, European Journal of Nanomedicine (2016)
96. Preparation and Characterization of Simvastatin Nanoparticles Using Rapid Expansion of Supercritical Solution (Ress) With Trifluoromethane, Journal of Supercritical Fluids (2016)
97. Preparation and Optimization of N-Trimethyl-O-Carboxymethyl Chitosan Nanoparticles for Delivery of Low-Molecular-Weight Heparin, Pharmaceutical Development and Technology (2016)
98. Preparation, Statistical Optimisation and in Vitro Characterisation of Poly (3-Hydroxybutyrate-Co-3-Hydroxyvalerate)/Poly (Lactic-Co-Glycolic Acid) Blend Nanoparticles for Prolonged Delivery of Teriparatide, Journal of Microencapsulation (2016)
99. Development and Validation of Rapid Stability-Indicating Rp-Hplc-Dad Method for the Quantification of Lapatinib and Mass Spectrometry Analysis of Degraded Products, Journal of Chromatographic Science (2015)
100. Development of Acid-Resistant Alginate/Trimethyl Chitosan Nanoparticles Containing Cationic Β-Cyclodextrin Polymers for Insulin Oral Delivery, AAPS PharmSciTech (2015)
101. Economic Burden of Hepatitis B Virus-Related Diseases: Evidence From Iran, Hepatitis Monthly (2015)
102. Elucidation of Molecular Mechanisms Behind the Self-Assembly Behavior of Chitosan Amphiphilic Derivatives Through Experiment and Molecular Modeling, Pharmaceutical Research (2015)
103. Elucidation of Molecular Mechanisms Behind the Self-Assembly Behavior of Chitosan Amphiphilic Derivatives Through Experiment and Molecular Modeling, Pharmaceutical Research (2015)
104. Fabrication and Characterization of Risperidone Implants As an Extended Antipsychotic Delivery System, Exploring the Role of Excipients, Journal of Pharmaceutical Innovation (2015)
105. Hyaluronic Acid Based Micelle for Articular Delivery of Triamcinolone, Preparation, in Vitro and in Vivo Evaluation, International Journal of Pharmaceutics (2015)
106. Oral Self-Nanoemulsifying Peptide Drug Delivery Systems: Impact of Lipase on Drug Release, Journal of Microencapsulation (2015)
107. Pluronic F127 Polymeric Micelles for Co-Delivery of Paclitaxel and Lapatinib Against Metastatic Breast Cancer: Preparation, Optimization and in Vitro Evaluation, Pharmaceutical Development and Technology (2015)
108. Development, Characterizations and Biocompatibility Evaluations of Intravitreal Lipid Implants, Jundishapur Journal of Natural Pharmaceutical Products (2014)
109. Poly[N-(2-Aminoethyl)Ethyleneimine] As a New Non-Viral Gene Delivery Carrier: The Effect of Two Protonatable Nitrogens in the Monomer Unit on Gene Delivery Efficiency, Journal of Pharmacy and Pharmaceutical Sciences (2014)
110. Physicochemical, Pharmaceutical and Biological Approaches Toward Designing Optimized and Efficient Hydrophobically Modified Chitosan-Based Polymeric Micelles As a Nanocarrier System for Targeted Delivery of Anticancer Drugs, Journal of Drug Targeting (2013)
111. Colon Specific Delivery of Budesonide Based on Triple Coated Pellets: In Vitro/In Vivo Evaluation, Acta Pharmaceutica (2012)
112. Development and Evaluation of a Monolithic Floating Drug Delivery System for Acyclovir, Chemical and Pharmaceutical Bulletin (2012)
113. Pectin Film Coated Pellets for Colon-Targeted Delivery of Budesonide: In-Vitro/In-Vivo Evaluation in Induced Ulcerative Colitis in Rat, Iranian Journal of Pharmaceutical Research (2012)
114. Development and Validation of a Rapid Hplc Method for Simultaneous Analysis of Budesonide and Its Novel Synthesized Hemiesters in Colon Specific Formulations, Research in Pharmaceutical Sciences (2011)
115. Development of Novel Budesonide Pellets Based on Codes™ Technology: In Vitro/In Vivo Evaluation in Induced Colitis in Rats, DARU, Journal of Pharmaceutical Sciences (2011)
116. Microencapsulation of Budesonide With Dextran by Spray Drying Technique for Colon-Targeted Delivery: An in Vitro/In Vivo Evaluation in Induced Colitis in Rat, Journal of Microencapsulation (2011)
117. Preparation and in Vitro/In Vivo Evaluation of Dextran Matrix Tablets of Budesonide in Experimental Ulcerative Colitis in Rats, Drug Delivery (2011)
118. Preparation of Budesonide-Dextran Conjugates Using Glutarate Spacer As a Colon-Targeted Drug Delivery System: In Vitro/In Vivo Evaluation in Induced Ulcerative Colitis, Journal of Drug Targeting (2011)
119. Colon Delivery of Budesonide Using Solid Dispersion in Dextran for the Treatment and Secondary Prevention of Ulcerative Colitis in Rat, International Journal of Preventive Medicine (2010)
120. Effectiveness of Budesonide-Succinate-Dextran Conjugate As a Novel Prodrug of Budesonide Against Acetic Acid-Induced Colitis in Rats, International Journal of Colorectal Disease (2010)
121. Permeation Enhancer Effect of Chitosan and Chitosan Derivatives: Comparison of Formulations As Soluble Polymers and Nanoparticulate Systems on Insulin Absorption in Caco-2 Cells, European Journal of Pharmaceutics and Biopharmaceutics (2008)
122. Preparation, Characterization and Antibacterial Activities of Chitosan, N-Trimethyl Chitosan (Tmc) and N-Diethylmethyl Chitosan (Demc) Nanoparticles Loaded With Insulin Using Both the Ionotropic Gelation and Polyelectrolyte Complexation Methods, International Journal of Pharmaceutics (2008)
123. Development and Validation of a Simple Hplc Method for Simultaneous in Vitro Determination of Amoxicillin and Metronidazole at Single Wavelength, Journal of Pharmaceutical and Biomedical Analysis (2007)
124. Influence of Β - Cyclodextrin Complexation on Lovastatin Release From Osmotic Pump Tablets (Opt), Daru (2007)
125. Solid Carriers for Improved Solubility of Glipizide in Osmotically Controlled Oral Drug Delivery System, Drug Development and Industrial Pharmacy (2007)