Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Establishment of an Optimized Chemotherapy-Induced Mouse Model for Premature Ovarian Failure: Protocol and Findings
Fardin Amidi
Fardin Amidi

Professor of Anatomical Sciences

Department Anatomy

School of Medicine

Tehran University of Medical Sciences

All Documents
1. Beneficial Role of Resveratrol on Oxidative Stress in Women With Polycystic Ovary Syndrome: A Randomized Controlled Trial, Reproductive Sciences (2025)
2. Diagnostic Accuracy of Plasma Microrna As a Potential Biomarker for Detection of Endometriosis, Systems Biology in Reproductive Medicine (2025)
3. Embryonic and Neonatal Outcomes Following Double Vitrification/Thawing: A Systematic Review and Meta-Analysis, BMC Pregnancy and Childbirth (2025)
4. Establishment of an Optimized Chemotherapy-Induced Mouse Model for Premature Ovarian Failure: Protocol and Findings, Aging (2025)
5. Exploring the Therapeutic Impact of Salvia Officinalis on Lipid and Oxidative Stress Markers in Patients With Polycystic Ovary Syndrome – a Randomized Placebo-Controlled Clinical Trial, BMC Complementary Medicine and Therapies (2025)
6. How Embryo Retention Affects Assisted Reproductive Technology Outcomes: A Systematic Review and Meta-Analysis, Archives of Gynecology and Obstetrics (2025)
7. Identification of Endometriosis Molecular Regulatory Axes Through Bioinformatics Analysis: Insights Into Lncrnas, Mirnas, and Mrnas, Physiology and Pharmacology (Iran) (2025)
8. Overview of the Effects of Astaxanthin on the Male Reproductive System Focusing on Mechanism Underling Its Action, European Journal of Pharmacology (2025)
9. Paper Strip Sensor Based on Γ-Fe2o3@Prussian Blue Nanozyme for H2o2 Detection, Nanomedicine Journal (2025)
10. Serum Levels of Angiopoietin-Like Protein 6 (Angptl6) in Iranian Women With Polycystic Ovary Syndrome, Journal of Reproduction and Infertility (2025)
11. Vaginal Probiotics As Therapeutic Adjuncts for Improving Embryo Transfer Success Rates: A Systematic Review and Meta-Analysis, BMC Pregnancy and Childbirth (2025)
12. Astaxanthin Improves Assisted Reproductive Technology Outcomes in Poor Ovarian Responders Through Alleviating Oxidative Stress, Inflammation, and Apoptosis: A Randomized Clinical Trial, Journal of Ovarian Research (2024)
13. Astaxanthin Supplementation Impact on Insulin Resistance, Lipid Profile, Blood Pressure, and Oxidative Stress in Polycystic Ovary Syndrome Patients: A Triple-Blind Randomized Clinical Trial, Phytotherapy Research (2024)
14. Astaxanthin Treatment Decreases Pro‐Inflammatory Cytokines and Improves Reproductive Outcomes in Patients With Polycystic Ovary Syndrome Undergoing Assisted Reproductive Technology: A Randomized Clinical Trial, Inflammopharmacology (2024)
15. Effect of Astaxanthin Supplementation on Female Fertility and Reproductive Outcomes: A Systematic Review and Meta-Analysis of Clinical and Animal Studies, Journal of Ovarian Research (2024)
16. Protective Effects of Astaxanthin on Post-Thaw Sperm Quality in Normozoospermic Men, Andrologia (2024)
17. Randomized Clinical Trial of Astaxanthin Supplement on Serum Inflammatory Markers and Er Stress-Apoptosis Gene Expression in Pbmcs of Women With Pcos, Journal of Cellular and Molecular Medicine (2024)
18. Resveratrol Ameliorates Mitochondrial Biogenesis and Reproductive Outcomes in Women With Polycystic Ovary Syndrome Undergoing Assisted Reproduction: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial, Journal of Ovarian Research (2024)
19. The Effect of Adipose-Derived Mesenchymal Stem Cell Transplantation on Ovarian Mitochondrial Dysfunction in Letrozole-Induced Polycystic Ovary Syndrome in Rats: The Role of Pi3k-Akt Signaling Pathway, Journal of Ovarian Research (2024)
20. The Effect of Astaxanthin After Varicocele Surgery on Antioxidant Status and Semen Quality in Infertile Men: A Triple-Blind Randomized Clinical Trial, Food Science and Nutrition (2024)
21. The Modulating Effects of Astaxanthin on Apoptosis in Women With Polycystic Ovarian Syndrome: A Randomized Clinical Trial, Avicenna Journal of Phytomedicine (2024)
22. Association of Dietary Total Antioxidant Capacity, Alternative Healthy Eating Index, and Dietary Inflammatory Index With Semen Quality in Men Seeking Infertility Treatment, Frontiers in Nutrition (2023)
23. Astaxanthin Ameliorates Inflammation, Oxidative Stress, and Reproductive Outcomes in Endometriosis Patients Undergoing Assisted Reproduction: A Randomized, Triple-Blind Placebo-Controlled Clinical Trial, Frontiers in Endocrinology (2023)
24. Astaxanthin Treatment Ameliorates Er Stress in Polycystic Ovary Syndrome Patients: A Randomized Clinical Trial, Scientific Reports (2023)
25. Drosophila Melanogaster Laboratory Rearing for Wolbachia-Based Control Programs, a Component of Dengue Control, Journal of Arthropod-Borne Diseases (2023)
26. Evaluating the Differential Expression of Mir-146A, Mir-222, and Mir-9 in Matched Serum and Follicular Fluid of Polycystic Ovary Syndrome Patients: Profiling and Predictive Value, International Journal of Molecular and Cellular Medicine (2023)
27. Evaluation of Nrf2/Are Signaling Pathway in the Presence of Pentoxifylline As a Cryoprotectant in Mouse Spermatogonial Stem Cells, Biopreservation and biobanking (2023)
28. Evaluation of Nrf2/Are Signaling Pathway in the Presence of Pentoxifylline As a Cryoprotectant in Mouse Spermatogonial Stem Cells, Biopreservation and biobanking (2023)
29. High Anti-Mullerian Hormone Strongly Correlates With Reproductive Outcomes in Women Undergoing Assisted Reproduction, Clinical Laboratory (2023)
30. In Vitro Complete Differentiation of Human Spermatogonial Stem Cells to Morphologic Spermatozoa Using a Hybrid Hydrogel of Agarose and Laminin, International Journal of Biological Macromolecules (2023)
31. Leukemia Inhibitory Factor’S Effect on the Growth and Survival of Sheep’S Follicles of Ovarian Tissue During Vitrification, Cell and Tissue Banking (2023)
32. Quercetin and Polycystic Ovary Syndrome; Inflammation, Hormonal Parameters and Pregnancy Outcome: A Randomized Clinical Trial, American Journal of Reproductive Immunology (2023)
33. Reproductive Outcomes of Water Pipe Smoking: A Scoping Review, Asian Pacific Journal of Reproduction (2023)
34. The Protective Effects of Astaxanthin on Pre-Antral Follicle Degeneration in Ovine Vitrified/Warmed Ovarian Tissue, Cryobiology (2023)
35. Astaxanthin Relieves Busulfan-Induced Oxidative Apoptosis in Cultured Human Spermatogonial Stem Cells by Activating the Nrf-2/Ho-1 Pathway, Reproductive Sciences (2022)
36. Bridging Potential of Taurine-Loading Pcl Conduits Transplanted With Henscs on Resected Sciatic Nerves, Regenerative Therapy (2022)
37. Covid-19 and Varicocele: The Possible Overlap Factors and the Common Therapeutic Approaches, American Journal of Reproductive Immunology (2022)
38. Investigating the Effect of Sulforaphane on Ampk/Akt/Nrf2 Pathway in Human Granulosa-Lutein Cells Under H2o2-Induced Oxidative Stress, European Journal of Obstetrics and Gynecology and Reproductive Biology (2022)
39. Metabolic Risk Factors of Ovarian Cancer: A Review, Jornal Brasileiro de Reproducao Assistida (2022)
40. Protective Roles of Seminal Plasma Exosomes and Microvesicles During Human Sperm Cryopreservation, Reproductive BioMedicine Online (2022)
41. Randomized Controlled Trial of Astaxanthin Impacts on Antioxidant Status and Assisted Reproductive Technology Outcomes in Women With Polycystic Ovarian Syndrome, Journal of Assisted Reproduction and Genetics (2022)
42. The Boosting Effects of Melatonin on the Expression of Related Genes to Oocyte Maturation and Antioxidant Pathways: A Polycystic Ovary Syndrome- Mouse Model, Journal of Ovarian Research (2022)
43. The Comparison the Impact of Flare-Up Gnrh Agonist With Delayed-Start Gnrh Antagonist Protocols on the Ivf Outcome of Poor Responder Patients: A Randomized Controlled Trial, International Journal of Women's Health and Reproduction Sciences (2022)
44. The Effect of Astaxanthin on Motility, Viability, Reactive Oxygen Species, Apoptosis, and Lipid Peroxidation of Human Spermatozoa During the Freezing-Thawing Process, Biopreservation and Biobanking (2022)
45. The Effect of Mitochondria-Targeted Antioxidant Mitoq10 on Redox Signaling Pathway Components in Pcos Mouse Model, Archives of Gynecology and Obstetrics (2022)
46. The Potential Relationship Between Different Human Female Reproductive Disorders and Sperm Quality in Female Genital Tract, Reproductive Sciences (2022)
47. The Role of Embryo Secreted Micrornas in Implantation, Journal of Knowledge and Health in Basic Medical Sciences (2022)
48. A Randomized Exploratory Trial to Assess the Effects of Resveratrol on Vegf and Tnf-Α 2 Expression in Endometriosis Women, Journal of Reproductive Immunology (2021)
49. Antioxidant Supplementations Ameliorate Pcos Complications: A Review of Rcts and Insights Into the Underlying Mechanisms, Journal of Assisted Reproduction and Genetics (2021)
50. Astaxanthin Protects Human Granulosa Cells Against Oxidative Stress Through Activation of Nrf2/Are Pathway and Its Downstream Phase Ii Enzymes, Cell Journal (2021)
51. Cell-Free Dna Discoveries in Human Reproductive Medicine: Providing a New Tool for Biomarker and Genetic Assays in Art, Journal of Assisted Reproduction and Genetics (2021)
52. Cell-Free Mtdna Level and Its Biomarker Potency for Art Outcome Are Different in Follicular Fluid of Pcos and Non-Pcos Women, Mitochondrion (2021)
53. Effect of Sulforaphane on Apoptosis, Reactive Oxygen Species and Lipids Peroxidation of Human Sperm During Cryopreservation, Cryobiology (2021)
54. Effect of Vitrification on Biogenesis Pathway and Expression of Development-Related Micrornas in Preimplantation Mouse Embryos, Cell and Tissue Banking (2021)
55. Male Factors: The Role of Sperm in Preimplantation Embryo Quality, Reproductive Sciences (2021)
56. Metformin Improves Epigenetic Modification Involved in Oocyte Growth and Embryo Development in Polycystic Ovary Syndrome Mice Model, Molecular Reproduction and Development (2021)
57. Overview of Biological Effects of Quercetin on Ovary, Phytotherapy Research (2021)
58. The Effect of Astaxanthin and Metformin on Oxidative Stress in Granulosa Cells of Balb C Mouse Model of Polycystic Ovary Syndrome, Reproductive Sciences (2021)
59. The Modulating Effects of Vitamin D on the Activity of Β-Catenin in the Endometrium of Women With Endometriosis: A Randomized Exploratory Trial, Gynecological Endocrinology (2021)
60. The Protective Effect of Sulforaphane Against Oxidative Stress in Granulosa Cells of Patients With Polycystic Ovary Syndrome (Pcos) Through Activation of Ampk/Akt/Nrf2 Signaling Pathway, Reproductive Biology (2021)
61. The Protective Effect of Sulforaphane Against Oxidative Stress Through Activation of Nrf2/Are Pathway in Human Granulosa Cells, Cell Journal (2021)
62. Altered Th1, Th2, Th17 Balance in Assisted Reproductive Technology Conceived Mice, Journal of Reproductive Immunology (2020)
63. Basal Characterization and in Vitro Differentiation of Putative Stem Cells Derived From the Adult Mouse Ovary, In Vitro Cellular and Developmental Biology - Animal (2020)
64. Does in Vitro Fertilization Affect the Expression of Mirnas and Their Biogenesis Pathway in Preimplantation Mouse Embryos?, Birth Defects Research (2020)
65. Effect of 1,25(Oh)2-Vitamin D3 on Expression and Phosphorylation of Progesterone Receptor in Cultured Endometrial Stromal Cells of Patients With Repeated Implantation Failure, Acta Histochemica (2020)
66. Exposing Mouse Oocytes to Mitoq During in Vitro Maturation Improves Maturation and Developmental Competence, Iranian Journal of Biotechnology (2020)
67. Extracellular Microrna Profiling in Human Follicular Fluid: New Biomarkers in Female Reproductive Potential, Journal of Assisted Reproduction and Genetics (2020)
68. Lighter Than Water Dispersive Liquid-Liquid Microextraction Coupled With High Performance Liquid Chromatography for Determination of Cholecalciferol and Calcifediol From Plasma, Analytical and Bioanalytical Chemistry Research (2020)
69. Potential of Auraptene in Improvement of Oocyte Maturation, Fertilization Rate, and Inflammation in Polycystic Ovary Syndrome Mouse Model, Reproductive Sciences (2020)
70. Resveratrol Treatment in Patients With Polycystic Ovary Syndrome Decreased Pro-Inflammatory and Endoplasmic Reticulum Stress Markers, American Journal of Reproductive Immunology (2020)
71. Antioxidant Effects of Quercetin in Freeze-Thawing Process of Mouse Spermatogonial Stem Cells, Asian Pacific Journal of Reproduction (2019)
72. Effects of Letrozole and Clomiphene Citrate on Wnt Signaling Pathway in Endometrium of Polycystic Ovarian Syndrome and Healthy Women, Biology of Reproduction (2019)
73. Effects of Resveratrol on Vegf & Hif1 Genes Expression in Granulosa Cells in the Angiogenesis Pathway and Laboratory Parameters of Polycystic Ovary Syndrome: A Triple-Blind Randomized Clinical Trial, Journal of Assisted Reproduction and Genetics (2019)
74. Expression Patterns for Tets, Lgr5 and Bmi1 in Cancer Stem-Like Cells Isolated From Human Colon Cancer, Avicenna Journal of Medical Biotechnology (2019)
75. Quercetin Protects Human Granulosa Cells Against Oxidative Stress Via Thioredoxin System, Reproductive Biology (2019)
76. The Modulating Effects of Resveratrol on the Expression of Mmp-2 and Mmp-9 in Endometriosis Women: A Randomized Exploratory Trial, Gynecological Endocrinology (2019)
77. Assessment of Pgc1α-Fndc5 Axis in Granulosa Cells of Pcos Mouse Model, Journal of Reproduction and Infertility (2018)
78. Association of Serum Content of 25-Hydroxy Vitamin D With Semen Quality in Normozoospermic and Oligoasthenoteratozoospermic Men, International Journal of Reproductive BioMedicine (2018)
79. Comparison of the Effects of Vitrification on Gene Expression of Mature Mouse Oocytes Using Cryotop and Open Pulled Straw, International Journal of Fertility and Sterility (2018)
80. Cryoprotective Effect of Resveratrol on Dna Damage and Crucial Human Sperm Messenger Rnas, Possibly Through 5′ Amp-Activated Protein Kinase Activation, Cell and Tissue Banking (2018)
81. Effect of Brain-Derived Neurotrophic Factor (Bdnf) on Sperm Quality of Normozoospermic Men, Human Fertility (2018)
82. Effect of Garlic (Allium Sativum) on Male Fertility: A Systematic Review, Journal of HerbMed Pharmacology (2018)
83. Evaluation of Prooxidant-Antioxidant Balance in in Vitro Fertilization-Conceived Mice, Clinical and Experimental Reproductive Medicine (2018)
84. Expression and Shedding of Cd44 in the Endometrium of Women With Endometriosis and Modulating Effects of Vitamin D: A Randomized Exploratory Trial, Journal of Steroid Biochemistry and Molecular Biology (2018)
85. Expression of Mir-15A, Mir-145, and Mir-182 in Granulosa-Lutein Cells, Follicular Fluid, and Serum of Women With Polycystic Ovary Syndrome (Pcos), Archives of Gynecology and Obstetrics (2018)
86. Roles of Methyltrienolone (R1881) in Akts and Ar Expression Patterns of Cultured Granulosa-Lutein Cells, Journal of Cellular Biochemistry (2018)
87. Study of Tnp1, Tekt1, and Plzf Genes Expression During an in Vitro Three-Dimensional Neonatal Male Mice Testis Culture, Iranian Biomedical Journal (2018)
88. The Effects of Letrozole and Clomiphene Citrate on Ligands Expression of Wnt3, Wnt7a, and Wnt8b in Proliferative Endometrium of Women With Polycystic Ovarian Syndrome, Gynecological Endocrinology (2018)
89. The Wnt/Β-Catenin Signaling in Endometriosis, the Expression of Total and Active Forms of Β-Catenin, Total and Inactive Forms of Glycogen Synthase Kinase-3Β, Wnt7a and Dickkopf-1, European Journal of Obstetrics and Gynecology and Reproductive Biology (2018)
90. Toxicity of Silver Nanoparticles on Different Tissues of Balb/C Mice, Life Sciences (2018)
91. Vitamin D3 Regulates Steroidogenesis in Granulosa Cells Through Amp-Activated Protein Kinase (Ampk) Activation in a Mouse Model of Polycystic Ovary Syndrome, Cell Biochemistry and Function (2018)
92. Bones Morphogenic Protein-4 and Retinoic Acid Combined Treatment Comparative Analysis for in Vitro Differentiation Potential of Murine Mesenchymal Stem Cells Derived From Bone Marrow and Adipose Tissue Into Germ Cells, Microscopy Research and Technique (2017)
93. Comparison of the Effects of Ham'sf10 and Αmem in Combination With Fbs or Bsa in Vitrification/Warming Solution on Quality and Viability of Sheep Ovarian Follicles, Reproduction in Domestic Animals (2017)
94. Differential Expression of Mir-93 and Mir-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating With Different Phenotypes, Scientific Reports (2017)
95. Effect of Brain-Derived Neurotrophic Factor on Sperm Function, Oxidative Stress and Membrane Integrity in Human, Andrologia (2017)
96. Effects of Melatonin on Oocyte Maturation in Pcos Mouse Model, Animal Science Journal (2017)
97. Evaluation of Intracellular Anion Superoxide Level, Heat Shock Protein A2 and Protamine Positive Spermatozoa Percentages in Teratoasthenozoospermia, International Journal of Reproductive BioMedicine (2017)
98. Expression of Akt1 Along With Akt2 in Granulosa-Lutein Cells of Hyperandrogenic Pcos Patients, Archives of Gynecology and Obstetrics (2017)
99. Modulation of Steroidogenesis by Vitamin D3 in Granulosa Cells of the Mouse Model of Polycystic Ovarian Syndrome, Systems Biology in Reproductive Medicine (2017)
100. Protective Features of Resveratrol on Human Spermatozoa Cryopreservation May Be Mediated Through 5’ Amp-Activated Protein Kinase Activation, Andrology (2017)
101. Role of Stromal Derived Factor-1A (Sdf-1A) for Spermatogenesis of Busulfan-Injured Rats, Reproductive Toxicology (2017)
102. Developmental Potential of Vitrified Mouse Testicular Tissue After Ectopic Transplantation, Cell Journal (2016)
103. Effect of Human Recombinant Granulocyte Colony-Stimulating Factor on Rat Busulfan-Induced Testis Injury, Journal of Molecular Histology (2016)
104. Effect of Nerve Growth Factor on Sperm Quality in Asthenozoosprmic Men During Cryopreservation, Reproductive Biology and Endocrinology (2016)
105. Effect of Selenium on Human Sperm Parameters After Freezing and Thawing Procedures, Asian Pacific Journal of Reproduction (2016)
106. Effect of Trolox on Sperm Quality in Normozospermia and Oligozospermia During Cryopreservation, Cryobiology (2016)
107. Efficacy of Crocus Sativus L. on Reduction of Cadmium-Induced Toxicity on Spermatogenesis in Adult Rats, Andrologia (2016)
108. Improving the Efficacy of Cryopreservation of Spermatogonia Stem Cells by Antioxidant Supplements, Cellular Reprogramming (2016)
109. Supplementation of Freezing and Thawing Media With Brain-Derived Neurotrophic Factor Protects Human Sperm From Freeze-Thaw-Induced Damage, Fertility and Sterility (2016)
110. The Role of Antioxidants in Sperm Freezing: A Review, Cell and Tissue Banking (2016)
111. Efect of Met-Anandamide on Prevention of Hyperactivation, Cryo-Capacitation and Acrosome Reaction in Ram Semen Cryopreservation; [Met-Anandamidin Koc Spermasinin Dondurulmasinda Hiperaktivasyon, Kryo-Kapasitasyon Ve Akrozom Reaksiyonunun Onlenmesi Uzerine Etkisi], Kafkas Universitesi Veteriner Fakultesi Dergisi (2015)
112. In Vitro Differentiation Process of Human Wharton’S Jelly Mesenchymal Stem Cells to Male Germ Cells in the Presence of Gonadal and Non-Gonadal Conditioned Media With Retinoic Acid, In Vitro Cellular and Developmental Biology - Animal (2015)
113. Isolation and Enrichment of Mouse Female Germ Line Stem Cells, Cell Journal (2015)
114. Male Germ-Like Cell Differentiation Potential of Human Umbilical Cord Wharton’S Jelly-Derived Mesenchymal Stem Cells in Co-Culture With Human Placenta Cells in Presence of Bmp4 and Retinoic Acid, Iranian Journal of Basic Medical Sciences (2015)
115. Nerve Growth Factor in Human Semen: Effect of Nerve Growth Factor on the Normozoospermic Men During Cryopreservation Process, Iranian Journal of Basic Medical Sciences (2015)
116. Planning Screw Insertion Trajectory in Lumbar Spinal Fusion Using Pre-Operative Ct Images, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society# EMBS (2015)
117. Stem Cell Isolation by a Morphology-Based Selection Method in Postnatal Mouse Ovary, Archives of Medical Science (2015)