Tehran University of Medical Sciences

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Faculty Members have conducted research related to the The Spectrum of Brca1 and Brca2 Pathogenic Sequence Variants in Middle Eastern, North African, and South European Countries
Ashraf Mohammadkhani
Ashraf Mohammadkhani

Associate Professor of Genetics

Digestive Diseases Research Center

Tehran University of Medical Sciences

All Documents
1. Causal Exposures in Pancreatic Cancer Incidence: Insights From Mendelian Randomization Studies, JGH Open (2025)
2. Alzheimer’S Disease and Infectious Agents: A Comprehensive Review of Pathogenic Mechanisms and Microrna Roles, Frontiers in Neuroscience (2024)
3. Burden of Disease Scenarios for 204 Countries and Territories, 2022–2050: A Forecasting Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
4. Burden of Disease Scenarios for 204 Countries and Territories, 2022–2050: A Forecasting Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
5. Global Burden and Strength of Evidence for 88 Risk Factors in 204 Countries and 811 Subnational Locations, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
6. Global Burden and Strength of Evidence for 88 Risk Factors in 204 Countries and 811 Subnational Locations, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
7. Global Burden of 288 Causes of Death and Life Expectancy Decomposition in 204 Countries and Territories and 811 Subnational Locations, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
8. Global Burden of 288 Causes of Death and Life Expectancy Decomposition in 204 Countries and Territories and 811 Subnational Locations, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
9. Global, Regional, and National Burden of Disorders Affecting the Nervous System, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet Neurology (2024)
10. Global, Regional, and National Burden of Disorders Affecting the Nervous System, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet Neurology (2024)
11. Protective Effect of Dehydroepiandrosterone (Dhea) on Pancreatic Cancer Through C-Reactive Protein (Crp) Production Inhibition, Reports of Biochemistry and Molecular Biology (2024)
12. Temporal Patterns of Cancer Burden in Asia, 1990–2019: A Systematic Examination for the Global Burden of Disease 2019 Study, The Lancet Regional Health - Southeast Asia (2024)
13. Temporal Patterns of Cancer Burden in Asia, 1990–2019: A Systematic Examination for the Global Burden of Disease 2019 Study, The Lancet Regional Health - Southeast Asia (2024)
14. A Form of Metabolic-Associated Fatty Liver Disease Associated With a Novel Lipa Variant, Archives of Iranian Medicine (2023)
15. Global, Regional, and National Burden of Rheumatoid Arthritis, 1990–2020, and Projections to 2050: A Systematic Analysis of the Global Burden of Disease Study 2021, The Lancet Rheumatology (2023)
16. Global, Regional, and National Incidence of Six Major Immune-Mediated Inflammatory Diseases: Findings From the Global Burden of Disease Study 2019, eClinicalMedicine (2023)
17. Global, Regional, and National Incidence of Six Major Immune-Mediated Inflammatory Diseases: Findings From the Global Burden of Disease Study 2019, eClinicalMedicine (2023)
18. Insights Into Organochlorine Pesticides Exposure in the Development of Cardiovascular Diseases: A Systematic Review, Archives of Iranian Medicine (2023)
19. Rna-Sequencing for Transcriptional Profiling of Whole Blood in Early Stage and Metastatic Pancreatic Cancer Patients, Cell Biology International (2023)
20. Climate Crises and Developing Vector-Borne Diseases: A Narrative Review, Iranian Journal of Public Health (2022)
21. Dynamic Changes in Kynurenine Pathway Metabolites in Multiple Sclerosis: A Systematic Review, Frontiers in Immunology (2022)
22. Global, Regional, and National Burden of Hepatitis B, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019, The Lancet Gastroenterology and Hepatology (2022)
23. Global, Regional, and National Burden of Hepatitis B, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019, The Lancet Gastroenterology and Hepatology (2022)
24. Gut Microbiota Modification Via Glucagon-Like Peptide-1 With Beneficial Neuroprotective Effects, Middle East Journal of Digestive Diseases (2022)
25. Pre-Clinical Studies Identifying Molecular Pathways of Neuroinflammation in Parkinson's Disease: A Systematic Review, Frontiers in Aging Neuroscience (2022)
26. Pre-Clinical Studies Identifying Molecular Pathways of Neuroinflammation in Parkinson's Disease: A Systematic Review, Frontiers in Aging Neuroscience (2022)
27. The Association of Dietary Intake and Plasma Fatty Acid Panel in Pancreatic Cancer Patients: Results From Golestan Cohort Study, Nutrition and Health (2022)
28. The Contribution of Gut-Brain Axis to Development of Neurological Symptoms in Covid-19 Recovered Patients: A Hypothesis and Review of Literature, Frontiers in Cellular and Infection Microbiology (2022)
29. Cigarette Smoking and Opium Use in Relation to the Oral Microbiota in Iran, Microbiology Spectrum (2021)
30. Circulating Plasma Fatty Acids and Risk of Pancreatic Cancer: Results From the Golestan Cohort Study, Clinical Nutrition (2021)
31. Dehydroepiandrosterone Modulates Oxidative Dna Damage in Pancreatic Cancer: A Case–Control Study, JGH Open (2021)
32. Diagnostic Significance of Serum Fatty Acid Synthase in Patients With Pancreatic Cancer, Middle East Journal of Digestive Diseases (2021)
33. Dietary Intake of Fatty Acids and Risk of Pancreatic Cancer: Golestan Cohort Study, Nutrition Journal (2021)
34. Gene Cluster Analysis of Marine Bacteria Seeking for Natural Anticancer Products, Jundishapur Journal of Natural Pharmaceutical Products (2021)
35. Seroprevalence of Immunoglobulin M and G Antibodies Against Sars-Cov-2 Virus: A Systematic Review and Meta-Analysis Study, Iranian Journal of Immunology (2021)
36. The Prognostic Value of Comorbidity for the Severity of Covid-19: A Systematic Review and Meta-Analysis Study, PLoS ONE (2021)
37. Critical Complications of Covid-19: A Descriptive Meta-Analysis Study, Reviews in Cardiovascular Medicine (2020)
38. Existing Antiviral Options Against Sars-Cov-2 Replication in Covid-19 Patients, Future Microbiology (2020)
39. Familial Adenomatous Polyposis: Diagnosis and Surveillance Strategies: Review Article, Tehran University Medical Journal (2020)
40. Heritability for Stroke: Essential for Taking Family History, Caspian Journal of Internal Medicine (2020)
41. Increasing Neutrophil Elastase and Decreasing Its Inhibitor, Alpha 1-Antitrypsin, in Patients With Non-Alcoholic Fatty Liver Disease, Hepatitis Monthly (2020)
42. Inflammatory Cytokines and Type 2 Diabetes, Koomesh (2020)
43. Oral Microbial Community Composition Is Associated With Pancreatic Cancer: A Case-Control Study in Iran, Cancer Medicine (2020)
44. The Effect of Vitamin D on Serum Asymmetric Dimethylarginine in Patients With Mild to Moderate Ulcerative Colitis, International Journal for Vitamin and Nutrition Research (2020)
45. An Increased Level of Aryl Hydrocarbon Receptor in Patients With Pancreatic Cancer, Middle East Journal of Digestive Diseases (2019)
46. Association of Delta-Aminolevulinic Acid Dehydratase Gene Variant With Serum Level of Alanine Aminotransferase, Hepatitis Monthly (2019)
47. Metabolomics Analysis of the Saliva in Patients With Chronic Hepatitis B Using Nuclear Magnetic Resonance: A Pilot Study, Iranian Journal of Basic Medical Sciences (2019)
48. Vitamin D Decreases Beck Depression Inventory Score in Patients With Mild to Moderate Ulcerative Colitis: A Double-Blind Randomized Placebo-Controlled Trial, Journal of Dietary Supplements (2019)
49. Kaempferol Increases Apoptosis in Human Acute Promyelocytic Leukemia Cells and Inhibits Multidrug Resistance Genes, Journal of Cellular Biochemistry (2018)
50. Mutations in Known and Novel Cancer Susceptibility Genes in Young Patients With Pancreatic Cancer, Archives of Iranian Medicine (2018)
51. On the Potential Role of Intestinal Microbial Community in Hepatocarcinogenesis in Chronic Hepatitis B, Cancer Medicine (2018)
52. Significant Snps Related to Telomere Length and Hepatocellular Carcinoma Risk in Chronic Hepatitis B Carriers, Asian Pacific Journal of Cancer Prevention (2018)
53. 8-Hydroxy-2’-Deoxyguanosin in Peripheral Leukocyte Associated With Hbsag in Patients With Chronic Hepatitis B, Jundishapur Journal of Microbiology (2017)
54. Genetics and Its Approach in the Diagnosis of Diseases With Familial History, Govaresh (2017)
55. Higher Serum Levels of Type I Interferon Receptor in Adults With Chronic Hepatitis B Leading to Hepatitis B Surface Antigen Clearance, Jundishapur Journal of Microbiology (2017)
56. Kaempferol Increases Apoptosis in Human Cervical Cancer Hela Cells Via Pi3k/Akt and Telomerase Pathways, Biomedicine and Pharmacotherapy (2017)
57. Pancreatic Cancer Is Associated With Peripheral Leukocyte Oxidative Dna Damage, Asian Pacific Journal of Cancer Prevention (2017)
58. Immune Responses to Hepatitis B Immunization 10–18 Years After Primary Vaccination: A Population-Based Cohort Study, Journal of Viral Hepatitis (2016)
59. Opium Use, Cigarette Smoking, and Alcohol Consumption in Relation to Pancreatic Cancer, Medicine (United States) (2016)
60. The Possible Impact of Sortilin in Reducing Hbsag Expression in Chronic Hepatitis B, Journal of Medical Virology (2016)
61. The Relationship Between Zinc Levels and Autism: A Systematic Review and Meta-Analysis, Iranian Journal of Child Neurology (2016)
62. Association of Mutations in the Basal Core Promoter and Pre-Core Regions of the Hepatitis B Viral Genome and Longitudinal Changes in Hbv Level in Hbeag Negative Individuals: Results From a Cohort Study in Northern Iran, Hepatitis Monthly (2015)
63. Central Obesity and Advanced Liver Stiffness in Hepatitis B: Result From Golestan Hepatitis B Cohort Study, Archives of Iranian Medicine (2015)
64. Downregulation of Plasma Mir-142-3P and Mir-26A-5P in Patients With Colorectal Carcinoma, International Journal of Cancer Management (2015)
65. Negative Association of Plasma Levels of Vitamin D and Mir-378 With Viral Load in Patients With Chronic Hepatitis B Infection, Hepatitis Monthly (2015)
66. Incarceration Is a Major Risk Factor for Blood-Borne Infection Among Intravenous Drug Users, Hepatitis Monthly (2011)
67. Hepatitis C Seroprevalence Among Intravenous Drug Users in Tehran, Journal of Research in Medical Sciences (2008)
68. Prevalence and Risk Factors of Hepatitis B Infection in Injection Drug Users, Tehran (2001-2002), Hepatitis Monthly (2008)