Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Display of B. Pumilus Chitinase on the Surface of B. Subtilis Spore As a Potential Biopesticide
Babak Negahdari
Babak Negahdari

Associate Professor of Medical Biotechnology

Department Medical Biotechnology

School of Advanced Technologies in Medicine

Metabolomics and Genomics Research Center

Endocrinology and Metabolism Research Institute

Tehran University of Medical Sciences

All Documents
1. Formulation, Characterization, and Potential Therapeutic Implications of Encapsulated Recombinant Alpha-Luffin in Niosomes, Current Pharmaceutical Biotechnology (2025)
2. Strategies for the Discovery and Design of Tissue Plasminogen Activators: Insights Into Bioengineering Objectives, Drug Development Research (2025)
3. Anticancer Effects of Simvastatin-Loaded Albumin Nanoparticles on Monolayer and Spheroid Models of Breast Cancer, Biochemical and Biophysical Research Communications (2024)
4. Determination of Morphine Using Carboxylated Multiwalled Carbon Nanotubes (Mwcnts) As the Label for an Immunochromatographic Assay (Ica), Analytical Letters (2024)
5. Milk-Derived Extracellular Vesicles: Biomedical Applications, Current Challenges, and Future Perspectives, Journal of Agricultural and Food Chemistry (2024)
6. Modulation of Fgf Pathway Signaling and Vascular Differentiation Using Designed Oligomeric Assemblies, Cell (2024)
7. Nanotechnology and Nano-Sized Tools: Newer Approaches to Circumvent Oncolytic Adenovirus Limitations, Pharmacology and Therapeutics (2024)
8. Oxaliplatin-Loaded Chitosan Nanoparticles Decorated With Cetuximab Single-Chain Variable Fragment for Human Colorectal Cancer Treatment, Cell Journal (2024)
9. Plasma Acylcarnitines and Amino Acids in Dyslipidemia: An Integrated Metabolomics and Machine Learning Approach, Journal of Diabetes and Metabolic Disorders (2024)
10. Treatment of Milk With Various Chemicals Differentially Affects the Physicochemical and Functional Characteristics of Extracellular Vesicles, Food Bioscience (2024)
11. Accurate Computational Design of Three-Dimensional Protein Crystals, Nature Materials (2023)
12. Amoxicillin-Docosahexaenoic Acid Encapsulated Chitosan-Alginate Nanoparticles As a Delivery System With Enhanced Biocidal Activities Against Helicobacter Pylori and Improved Ulcer Healing, Frontiers in Microbiology (2023)
13. An Anti-Taz Monoclonal Antibody Recognizing Cell Surface Expressed Taz Protein in Human Tumor Cells, Avicenna Journal of Medical Biotechnology (2023)
14. Antibacterial and Immunoregulatory Effects of Metformin Against Helicobacter Pylori Infection in Rat Model, BioMed Research International (2023)
15. Combining Non-Thermal Processing Techniques With Edible Coating Materials: An Innovative Approach to Food Preservation, Coatings (2023)
16. Design of a Dual-Function Agent by Fusing a Designed Anti-Vegf-A Binder and Cpg-2 Enzyme, Journal of Biomolecular Structure and Dynamics (2023)
17. Heterologous Prime-Boost Vaccination Using Adenovirus and Albumin Nanoparticles As Carriers for Human Papillomavirus 16 E7 Epitope, Current Pharmaceutical Biotechnology (2023)
18. Hnf4α Is Possibly the Missing Link Between Epithelial–Mesenchymal Transition and Warburg Effect During Hepatocarcinogenesis, Cancer Science (2023)
19. Mixed Oral Biofilms Are Controlled by the Interspecies Interactions of Fusobacterium Nucleatum, Oral Diseases (2023)
20. Nanovaccines for Cancer Immunotherapy: Focusing on Complex Formation Between Adjuvant and Antigen, International Immunopharmacology (2023)
21. Optimization of the Expression of Recombinant Cetuximab Single-Chain Fragment Variable and Comparative Its Purification With Magnetic Nanoparticles and Conventional Fast Protein Liquid Chromatography, Biointerface Research in Applied Chemistry (2023)
22. Polymeric Nanoparticles for Dna Vaccine-Based Cancer Immunotherapy: A Review, Biotechnology Letters (2023)
23. Silica Nps–Cytotoxicity Cross-Talk: Physicochemical Principles and Cell Biology Responses, Silicon (2023)
24. Vegfr2 Mimicking Peptide Inhibits the Proliferation of Human Umbilical Vein Endothelial Cells (Huvecs) by Blocking Vegf, Anti-Cancer Agents in Medicinal Chemistry (2023)
25. Bacteria-Derived Chimeric Toxins As Potential Anticancer Agents, Frontiers in Oncology (2022)
26. Binder Design for Targeting Sars-Cov-2 Spike Protein: An in Silico Perspective, Gene Reports (2022)
27. Clinical and Diagnostic Potential of Regulatory T Cell Markers: From Bench to Bedside, Transplant Immunology (2022)
28. Exosomal Micrornas and Long Noncoding Rnas: Novel Mediators of Drug Resistance in Lung Cancer, Journal of Cellular Physiology (2022)
29. Exosomal Micrornas and Long Noncoding Rnas: Novel Mediators of Drug Resistance in Lung Cancer, Journal of Cellular Physiology (2022)
30. Gastrointestinal Cancer Drug Resistance: The Role of Exosomal Mirnas, Molecular Biology Reports (2022)
31. Gastrointestinal Cancer Drug Resistance: The Role of Exosomal Mirnas, Molecular Biology Reports (2022)
32. Hepatogenesis and Hepatocarcinogenesis: Alignment of the Main Signaling Pathways, Journal of Cellular Physiology (2022)
33. Monoclonal Antibody Against Sortilin Induces Apoptosis in Human Breast Cancer Cells, Avicenna Journal of Medical Biotechnology (2022)
34. Oncolytic Virotherapy As Promising Immunotherapy Against Cancer: Mechanisms of Resistance to Oncolytic Viruses, Future Oncology (2022)
35. Rational Design of Anti-Angiogenic Peptides to Inhibit Vegf/Vegfr2 Interactions for Cancer Therapeutics, Anti-Cancer Agents in Medicinal Chemistry (2022)
36. Screening of Candidate Genes Associated With High Titer Production of Oncolytic Measles Virus Based on Systems Biology Approach, Virus Genes (2022)
37. Surface Modification of Titanium Implants Via Electrospinning of Sericin and Equisetum Arvense Enhances the Osteogenic Differentiation of Stem Cells, International Journal of Polymeric Materials and Polymeric Biomaterials (2022)
38. Vitamin D Receptor Gene Polymorphisms and Risk of Breast Cancer in Iranian Women, Annals of Medicine and Surgery (2022)
39. Advanced Therapeutic Modalities in Hepatocellular Carcinoma: Novel Insights, Journal of Cellular and Molecular Medicine (2021)
40. Autoimmune Manifestations Among 461 Patients With Monogenic Inborn Errors of Immunity, Pediatric Allergy and Immunology (2021)
41. Autoimmune Manifestations Among 461 Patients With Monogenic Inborn Errors of Immunity, Pediatric Allergy and Immunology (2021)
42. Chimeric Antigen Receptor T-Cell Therapy for Breast Cancer, Future Oncology (2021)
43. Combined Therapy of Mesenchymal Stem Cells With a Glp-1 Receptor Agonist, Liraglutide, on an Inflammatory-Mediated Diabetic Non-Human Primate Model, Life Sciences (2021)
44. Evaluating Gold Nanoparticles Parameters in Competitive Immunochromatographich Assay Via Dot Blot and Bradford Assay As New Approaches, Microchemical Journal (2021)
45. Exosomal Noncoding Rnas: Key Players in Glioblastoma Drug Resistance, Molecular and Cellular Biochemistry (2021)
46. Exosomal Noncoding Rnas: Key Players in Glioblastoma Drug Resistance, Molecular and Cellular Biochemistry (2021)
47. Heterologous Administration of Hpv16 E7 Epitope-Loaded Nanocomplexes Inhibits Tumor Growth in Mouse Model, International Immunopharmacology (2021)
48. Immunotherapy for Breast Cancer Treatment, Iranian Biomedical Journal (2021)
49. Introducing Electrospray As a Potent Technique to Deliver Chitosan/Pdna Nanoparticles to Eukaryotic Cells, Journal of Nano Research (2021)
50. Oncolytic Virotherapy: Challenges and Solutions, Current Problems in Cancer (2021)
51. Virus Against Virus: Strategies for Using Adenovirus Vectors in the Treatment of Hpv-Induced Cervical Cancer, Acta Pharmacologica Sinica (2021)
52. A Lectin-Coupled Porous Silicon-Based Biosensor: Label-Free Optical Detection of Bacteria in a Real-Time Mode, Scientific Reports (2020)
53. Autoimmunity As a Target for Chimeric Immune Receptor Therapy: A New Vision to Therapeutic Potential, Blood Reviews (2020)
54. Directed Differentiation of Regulatory T Cells From Naive T Cells and Prevention of Their Inflammation-Mediated Instability Using Small Molecules, Clinical and Experimental Immunology (2020)
55. Genetically Engineered Mesenchymal Stem Cells: Targeted Delivery of Immunomodulatory Agents for Tumor Eradication, Cancer Gene Therapy (2020)
56. Genetically Engineered Mesenchymal Stem Cells: Targeted Delivery of Immunomodulatory Agents for Tumor Eradication, Cancer Gene Therapy (2020)
57. Helicobacter Pylori Antibiotic Resistance and Correlation With Caga Motifs and Homb Gene, Postgraduate Medicine (2020)
58. Monogenic Primary Immunodeficiency Disorder Associated With Common Variable Immunodeficiency and Autoimmunity, International Archives of Allergy and Immunology (2020)
59. Monogenic Primary Immunodeficiency Disorder Associated With Common Variable Immunodeficiency and Autoimmunity, International Archives of Allergy and Immunology (2020)
60. Overcoming the Blood-Brain Barrier in Neurodegenerative Disorders and Brain Tumours, IET Nanobiotechnology (2020)
61. Silk Fibroin/Alumina Nanoparticle Scaffold Using for Osteogenic Differentiation of Rabbit Adipose-Derived Stem Cells, Materialia (2020)
62. Strategies for Enhancing Intratumoral Spread of Oncolytic Adenoviruses, Pharmacology and Therapeutics (2020)
63. Applications of Drug Anesthesia in Control Chronic Pain, Journal of Investigative Surgery (2019)
64. Cea Plasmid As Therapeutic Dna Vaccination Against Colorectal Cancer, Iranian Journal of Immunology (2019)
65. Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort, Journal of Allergy and Clinical Immunology: In Practice (2019)
66. Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort, Journal of Allergy and Clinical Immunology: In Practice (2019)
67. Electrospun Core-Sheath Poly(Vinyl Alcohol)/Silk Fibroin Nanofibers With Rosuvastatin Release Functionality for Enhancing Osteogenesis of Human Adipose-Derived Stem Cells, Materials Science and Engineering C (2019)
68. Fusobacterium Nucleatum and Colorectal Cancer: A Mechanistic Overview, Journal of Cellular Physiology (2019)
69. Gold Nanoparticles and Hepatitis B Virus, Artificial Cells# Nanomedicine and Biotechnology (2019)
70. Gold Nanoparticles and Hepatitis B Virus, Artificial Cells# Nanomedicine and Biotechnology (2019)
71. In Situ Forming Hydrogels Based on Polyethylene Glycol Itaconate for Tissue Engineering Application, Bulletin of Materials Science (2019)
72. Oncolytic Adenovirus: A Tool for Cancer Therapy in Combination With Other Therapeutic Approaches, Journal of Cellular Physiology (2019)
73. Osteogenic Potential of Rosuvastatin Immobilized on Silk Fibroin Nanofibers Using Argon Plasma Treatment, Biomedical Materials (Bristol) (2019)
74. Protective Responses of an Engineered Pspa Recombinant Antigen Against Streptococcus Pneumoniae, Biotechnology Reports (2019)
75. Regulation of Tumor Angiogenesis by Micrornas: State of the Art, Journal of Cellular Physiology (2019)
76. Targeting Sirna in Colorectal Cancer Therapy: Nanotechnology Comes Into View, Journal of Cellular Physiology (2019)
77. The Bioextraction of Bioplastics With Focus on Polyhydroxybutyrate: A Review, International Journal of Environmental Science and Technology (2019)
78. The Evaluation of Neutropenia in Common Variable Immune Deficiency Patients, Expert Review of Clinical Immunology (2019)
79. Advanced Biotechnology in Biorefinery: A New Insight Into Municipal Waste Management to the Production of High-Value Products, International Journal of Environmental Science and Technology (2018)
80. Antinociceptive Synergistic Interaction Between Achillea Millefolium and Origanum Vulgare L. Extract Encapsulated in Liposome in Rat, Artificial Cells# Nanomedicine and Biotechnology (2018)
81. Autoimmunity and Its Association With Regulatory T Cells and B Cell Subsets in Patients With Common Variable Immunodeficiency, Allergologia et Immunopathologia (2018)
82. Biosensors for the Detection of Environmental and Urban Pollutions, Journal of Cellular Biochemistry (2018)
83. Clinical, Immunologic, and Genetic Spectrum of 696 Patients With Combined Immunodeficiency, Journal of Allergy and Clinical Immunology (2018)
84. Clinical, Immunologic, and Genetic Spectrum of 696 Patients With Combined Immunodeficiency, Journal of Allergy and Clinical Immunology (2018)
85. Design, Expression and Evaluation of Novel Chimeric Protein Constructed From Colorectal Tumor-Associated Antigen, Journal of Cellular Biochemistry (2018)
86. Diabetic Ulcer Regeneration: Stem Cells, Biomaterials, Growth Factors, Artificial Cells# Nanomedicine and Biotechnology (2018)
87. Incorporation of Nanoalumina Improves Mechanical Properties and Osteogenesis of Hydroxyapatite Bioceramics, ACS Biomaterials Science and Engineering (2018)
88. Isolation and Characterization of Mesenchymal Stem Cells and Its Antitumor Application on Ovarian Cancer Cell Line, Artificial Cells# Nanomedicine and Biotechnology (2018)
89. Lung Regeneration Using Amniotic Fluid Mesenchymal Stem Cells, Artificial Cells# Nanomedicine and Biotechnology (2018)
90. Nanoparticles As New Tools for Inhibition of Cancer Angiogenesis, Journal of Cellular Physiology (2018)
91. Nanotechnology Application for Pain Therapy, Artificial Cells# Nanomedicine and Biotechnology (2018)
92. Nanotechnology Application to Local Anaesthesia (La), Artificial Cells# Nanomedicine and Biotechnology (2018)
93. Overexpression of Mir-219 Promotes Differentiation of Human Induced Pluripotent Stem Cells Into Pre-Oligodendrocyte, Journal of Chemical Neuroanatomy (2018)
94. Porous Mnfe2o4@Sio2 Magnetic Glycopolymer: A Multivalent Nanostructure for Efficient Removal of Bacteria From Aqueous Solution, Ecotoxicology and Environmental Safety (2018)
95. Stem Cell Therapy: A New Therapeutic Option for Cardiovascular Diseases, Journal of Cellular Biochemistry (2018)
96. Systematic Investigation for Underlying Causes of Recurrent Infections in Children: Surveillance of Primary Immunodeficiency, European Annals of Allergy and Clinical Immunology (2018)
97. ‘Inversed Turkevich’ Method for Tuning the Size of Gold Nanoparticles: Evaluation the Effect of Concentration and Temperature, Nanomedicine Research Journal (2018)
98. Cardiac Failure Detection in 30 Minutes: New Approach Based on Gold Nanoparticles, Journal of Microencapsulation (2017)
99. Cardioprotective Effect of Magnetic Hydrogel Nanocomposite Loaded N,Α-L-Rhamnopyranosyl Vincosamide Isolated From Moringa Oleifera Leaves Against Doxorubicin-Induced Cardiac Toxicity in Rats: In Vitro and in Vivo Studies, Journal of Microencapsulation (2017)
100. Designing a Chimeric Vaccine Against Colorectal Cancer, International Journal of Cancer Management (2017)
101. Drug Anesthesia for Children Undergoing Magnetic Resonance Imaging: A Review, Biomedicine and Pharmacotherapy (2017)
102. Effects of Mesenchymal Stem Cell-Derived Exosomes on Angiogenesis in Regenerative Medicine, Current Regenerative Medicine (2017)
103. Fabrication and Characterization of Nanofibrous Tricuspid Valve Scaffold Based on Polyurethane for Heart Valve Tissue Engineering, Nanomedicine Research Journal (2017)
104. Glucose Reinforced Fe3o4@Cellulose Mediated Amino Acid: Reusable Magnetic Glyconanoparticles With Enhanced Bacteria Capture Efficiency, Carbohydrate Polymers (2017)
105. Heart Targeted Nanoliposomal/Nanoparticles Drug Delivery: An Updated Review, Biomedicine and Pharmacotherapy (2017)
106. Measurement of Health-Related Quality of Life in Primary Antibody-Deficient Patients, Immunological Investigations (2017)
107. Melatonin As an Angiogenesis Inhibitor to Combat Cancer: Mechanistic Evidence, Toxicology and Applied Pharmacology (2017)
108. New Therapeutic Approach by Sirolimus for Enteropathy Treatment in Patients With Lrba Deficiency, European Annals of Allergy and Clinical Immunology (2017)
109. New Therapeutic Approach by Sirolimus for Enteropathy Treatment in Patients With Lrba Deficiency, European Annals of Allergy and Clinical Immunology (2017)
110. Paediatric Nanofibrous Bioprosthetic Heart Valve, IET Nanobiotechnology (2017)
111. Recent Advances in Cardiac Regeneration: Stem Cell, Biomaterial and Growth Factors, Biomedicine and Pharmacotherapy (2017)
112. Recent Advances in Magnetoliposome for Heart Drug Delivery, Artificial Cells# Nanomedicine and Biotechnology (2017)
113. Recent Progresses in Plastic Surgery Using Adipose-Derived Stem Cells, Biomaterials and Growth Factors, Journal of Microencapsulation (2017)
114. Retraction Notice to “Recent Advances in Cardiac Regeneration: Stem Cell, Biomaterial and Growth Factors” [Biomed. Pharmacother. 87 (2017) 37–45](S0753332216316316)(10.1016/J.Biopha.2016.12.071), Biomedicine and Pharmacotherapy (2017)
115. Role of Protease and Protease Inhibitors in Cancer Pathogenesis and Treatment, Biomedicine and Pharmacotherapy (2017)
116. Stem Cell, Biomaterials and Growth Factors Therapy for Hepatocellular Carcinoma, Biomedicine and Pharmacotherapy (2017)
117. Synthesis, Properties and Biomedical Applications of Carbon-Based Quantum Dots: An Updated Review, Biomedicine and Pharmacotherapy (2017)
118. Cohort of Iranian Patients With Congenital Agammaglobulinemia: Mutation Analysis and Novel Gene Defects, Expert Review of Clinical Immunology (2016)
119. Colon Cancer Targeting Using Conjugates Biomaterial 5-Flurouracil, Biomedicine and Pharmacotherapy (2016)
120. Design and Fabrication of a Nanofibrous Polycaprolactone Tubular Nerve Guide for Peripheral Nerve Tissue Engineering Using a Two-Pole Electrospinning System, Biomedical Materials (Bristol) (2016)
121. Identification of Novel Bacterial Dna Gyrase Inhibitors: An in Silico Study, Research in Pharmaceutical Sciences (2016)
122. Managing Patients With Side Effects and Adverse Events to Immunoglobulin Therapy, Expert Review of Clinical Pharmacology (2016)
123. Natriuretic Peptides and Their Therapeutic Potential in Heart Failure Treatment: An Updated Review, Cellular and Molecular Biology (2016)
124. Production of Human Epidermal Growth Factor Using Adenoviral Based System, Research in Pharmaceutical Sciences (2016)
125. Synthesis and Characterization of Chrysin-Loaded Pcl-Peg-Pcl Nanoparticle and Its Effect on Breast Cancer Cell Line, Biomedicine and Pharmacotherapy (2016)
126. A Structural Model of the Anaphase Promoting Complex Co-Activator (Cdh1) and in Silico Design of Inhibitory Compounds, Research in Pharmaceutical Sciences (2015)
127. Erratum to Evaluation of Optimal Concentration and Exposure Duration of Valproic Acid Alone or in Combination With Viraductin to Augment Adenovirus Transduction in Human Adipose Stem Cells [Cytotherapy, 16, (2014), 612-618], Cytotherapy (2015)