Tehran University of Medical Sciences

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Faculty Members have conducted research related to the Comparison of Outcomes With Midodrine and Fludrocortisone for Objective Recurrence in Treating Syncope (Comforts Trial): Rationale and Design for a Multi-Center Randomized Controlled Trial
Saeed Sadeghian
Saeed Sadeghian

Professor of Cardiology

Department Cardiology

School of Medicine

Tehran Heart Center

Tehran University of Medical Sciences

All Documents
1. Contribution of Genetic Variants in the Development of Familial Premature Coronary Artery Disease in a Cohort of Cardiac Patients, Clinical Genetics (2024)
2. Determining the Recurrence Rate of Premature Ventricular Complexes and Idiopathic Ventricular Tachycardia After Radiofrequency Catheter Ablation With the Help of Designing a Machine-Learning Model, Regenerative Therapy (2024)
3. Effectiveness of Applying Green Heart, a Smartphone-Based Self-Management Intervention to Control Smoking: A Randomized Clinical Trial, Archives of Iranian medicine (2024)
4. Epidemiology and Prevalence of Dyslipidemia Among Adult Population of Tehran: The Tehran Cohort Study, Archives of Iranian Medicine (2024)
5. Epidemiology of Substance and Opium Use Among Adult Residents of Tehran; a Comprehensive Report From Tehran Cohort Study (Tecs), BMC Psychiatry (2024)
6. Global Age-Sex-Specific Mortality, Life Expectancy, and Population Estimates in 204 Countries and Territories and 811 Subnational Locations, 1950–2021, and the Impact of the Covid-19 Pandemic: A Comprehensive Demographic Analysis for the Global Burden of Disease Study 2021, The Lancet (2024)
7. Global, Regional, and National Burden of Disorders Affecting the Nervous System, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021, The Lancet Neurology (2024)
8. Heart Surgery Over Two Decades: What We Have Learned About Results and Changing Risks, BMC cardiovascular disorders (2024)
9. Risk Factor Profile and Outcomes of Premature Acute Coronary Syndrome After Percutaneous Coronary Intervention: A 1-Year Prospective Design, Clinical Cardiology (2024)
10. Risk Factor Profile and Outcomes of Premature Acute Coronary Syndrome After Percutaneous Coronary Intervention: A 1-Year Prospective Design, Clinical Cardiology (2024)
11. Sex-Based Association Between High-Density Lipoprotein Cholesterol and Adverse Outcomes After Coronary Artery Bypass Grafting, BMC Cardiovascular Disorders (2024)
12. The Effectiveness of Green Heart Application to Manage Modifiable Risk Factors of Coronary Artery Disease in Tehran Heart Center: Study Protocol for a Randomized Controlled Trial, Heliyon (2024)
13. Trans-Apical Catheter Ablation of Ventricular Tachycardia in a Patient With Metallic Aortic and Mitral Valves, Journal of Cardiothoracic Surgery (2024)
14. 7-Year Outcomes in Diabetic Patients After Coronary Artery Bypass Graft in a Developing Country, BMC Cardiovascular Disorders (2023)
15. A Realistic Approach to Evaluating the Effect of Baseline Lipid Profile in Postcoronary Artery Bypass Grafting Surgery, Clinical Cardiology (2023)
16. Age and Gender Differences of Basic Electrocardiographic Values and Abnormalities in the General Adult Population; Tehran Cohort Study, BMC Cardiovascular Disorders (2023)
17. Atorvastatin Versus Placebo in Icu Patients With Covid-19: Ninety-Day Results of the Inspiration-S Trial, Thrombosis and Haemostasis (2023)
18. Brain Mri and Eeg Overemployment in Patients With Vasovagal Syncope: Results From a Tertiary Syncope Unit, BMC Cardiovascular Disorders (2023)
19. Clinical Associations of Injuries Caused by Vasovagal Syncope: A Cohort Study From a Tertiary Syncope Unit, Journal of the American Heart Association (2023)
20. Clinical Outcomes of Subcutaneous Implantable Cardiac Defibrillator Implantation – Iran Sicd Registry, PACE - Pacing and Clinical Electrophysiology (2023)
21. Clinical Outcomes of Subcutaneous Implantable Cardiac Defibrillator Implantation – Iran Sicd Registry, PACE - Pacing and Clinical Electrophysiology (2023)
22. Epidemiology and Prevalence of Tobacco Use in Tehran; a Report From the Recruitment Phase of Tehran Cohort Study, BMC Public Health (2023)
23. Factor V Leiden But Not the Factor Ii 20210G>A Mutation Is a Risk Factor for Premature Coronary Artery Disease: A Case-Control Study in Iran, Research and Practice in Thrombosis and Haemostasis (2023)
24. Global Investments in Pandemic Preparedness and Covid-19: Development Assistance and Domestic Spending on Health Between 1990 and 2026, The Lancet Global Health (2023)
25. Global, Regional, and National Burden of Meningitis and Its Aetiologies, 1990–2019: A Systematic Analysis for the Global Burden of Disease Study 2019, The Lancet Neurology (2023)
26. Global, Regional, and National Incidence of Six Major Immune-Mediated Inflammatory Diseases: Findings From the Global Burden of Disease Study 2019, eClinicalMedicine (2023)
27. Metabolic Risk Factors Attributed Burden in Iran at National and Subnational Levels, 1990 to 2019, Frontiers in Public Health (2023)
28. Opium As a Risk Factor for Early-Onset Coronary Artery Disease: Results From the Milano-Iran (Miran) Study, PLoS ONE (2023)
29. Opium Consumption and Long-Term Outcomes of Cabg Surgery in Patients Without Modifiable Risk Factors, Frontiers in Surgery (2023)
30. Predictors of Mortality and Clinical Outcomes Following Implantable Cardioverter-Defibrillator Therapy in Elderly Patients: A Retrospective Single-Center Cohort Study, Health Science Reports (2023)
31. Prevalence of Obesity and Overweight in an Adult Population of Tehran Metropolis, Journal of Diabetes and Metabolic Disorders (2023)
32. Prevalence, Years Lived With Disability, and Trends in Anaemia Burden by Severity and Cause, 1990–2021: Findings From the Global Burden of Disease Study 2021, The Lancet Haematology (2023)
33. The Prognostic Role of the Low and Very Low Baseline Ldl-C Level in Outcomes of Patients With Cardiac Revascularization; Comparative Registry-Based Cohort Design, Journal of Cardiothoracic Surgery (2023)
34. The Unfinished Agenda of Communicable Diseases Among Children and Adolescents Before the Covid-19 Pandemic, 1990–2019: A Systematic Analysis of the Global Burden of Disease Study 2019, The Lancet (2023)
35. Association Between Cognitive Representation of Illness and the Outcome of Patients With Premature Coronary Artery Disease, Journal of Psychosomatic Research (2022)
36. Atorvastatin Versus Placebo in Patients With Covid-19 in Intensive Care: Randomized Controlled Trial, The BMJ (2022)
37. Cardiovascular Health Effects of Wearing a Particulate-Filtering Respirator to Reduce Particulate Matter Exposure: A Randomized Crossover Trial, Journal of Human Hypertension (2022)
38. Compression Stockings for Treating Vasovagal Syncope (Comforts-Ii) Trial: Rationale and Design of a Triple-Blind, Multi-Center, Randomized Controlled Trial, American Heart Journal (2022)
39. Compression Stockings for Treating Vasovagal Syncope (Comforts-Ii) Trial: Rationale and Design of a Triple-Blind, Multi-Center, Randomized Controlled Trial, American Heart Journal (2022)
40. Effect of Different Blood Groups on Long-Term Outcomes of Surgical Revascularisation, Heart Lung and Circulation (2022)
41. Effect of Postoperative Atrial Fibrillation on Early and Mid-Term Outcomes of Coronary Artery Bypass Graft Surgery, European Journal of Cardio-thoracic Surgery (2022)
42. Global Mortality Associated With 33 Bacterial Pathogens in 2019: A Systematic Analysis for the Global Burden of Disease Study 2019, The Lancet (2022)
43. Implementation of Supervised Physical Training to Reduce Vasovagal Syncope Recurrence: A Randomized Controlled Trial, Journal of Cardiovascular Electrophysiology (2022)
44. Machine Learning Algorithms for Predicting Mortality After Coronary Artery Bypass Grafting, Frontiers in Cardiovascular Medicine (2022)
45. Neonate, Infant, and Child Mortality in North Africa and Middle East by Cause: An Analysis for the Global Burden of Disease Study 2019, Archives of Iranian Medicine (2022)
46. Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery Outcomes in Patients With Severe Left Ventricle Dysfunction: Inverse Probability Weighted Study, BMC Cardiovascular Disorders (2022)
47. Orphan Gpr26 Counteracts Early Phases of Hyperglycemia-Mediated Monocyte Activation and Is Suppressed in Diabetic Patients, Biomedicines (2022)
48. Outcome of Percutaneous Coronary Intervention in Old Patients Presenting With Acute Coronary Syndrome, Archives of Iranian Medicine (2022)
49. Predictors of In-Hospital Mortality in Diabetic Patients With Non-St-Elevation Myocardial Infarction, Egyptian Heart Journal (2022)
50. Prevalence, Awareness, Treatment, and Control of Hypertension Among Adult Residents of Tehran: The Tehran Cohort Study, Global Heart (2022)
51. Prevalence, Awareness, Treatment, and Control of Type 2 Diabetes Mellitus Among the Adult Residents of Tehran: Tehran Cohort Study, BMC Endocrine Disorders (2022)
52. Prognostic Significance of Positive Family History in Outcomes After Coronary Artery Bypass Grafting: Do We Need to Update Our Assumptions?, Journal of Cardiothoracic Surgery (2022)
53. Sex Difference in the Risk Factor Distributions and Outcomes After Coronary Artery Bypass Graft Surgery in the Young Population, European Journal of Cardio-thoracic Surgery (2022)
54. The Association Between Different Body Mass Index Levels and Midterm Surgical Revascularization Outcomes, PLoS ONE (2022)
55. The Global Burden of Adolescent and Young Adult Cancer in 2019: A Systematic Analysis for the Global Burden of Disease Study 2019, The Lancet Oncology (2022)
56. Utility of the Cha2ds2-Vasc Score in Prediction of Postoperative Atrial Fibrillation After Coronary Artery Bypass Graft Surgery, Journal of Cardiothoracic and Vascular Anesthesia (2022)
57. Atomoxetine As an Adjunct to Nonpharmacological Treatments for Preventing Vasovagal Attacks in Patients With Recurrent Vasovagal Syncope: A Pilot Randomized-Controlled Trial, IJC Heart and Vasculature (2021)
58. Clinical Implications and Indicators of Mortality Among Patients Hospitalized With Concurrent Covid-19 and Myocardial Infarction, Turk Kardiyoloji Dernegi Arsivi (2021)
59. Comparison of Outcomes With Midodrine and Fludrocortisone for Objective Recurrence in Treating Syncope (Comforts Trial): Rationale and Design for a Multi-Center Randomized Controlled Trial, American Heart Journal (2021)
60. Comparison of Outcomes With Midodrine and Fludrocortisone for Objective Recurrence in Treating Syncope (Comforts Trial): Rationale and Design for a Multi-Center Randomized Controlled Trial, American Heart Journal (2021)
61. Comparison of Trinitroglycerin and Adenosine As Provocative Agents for Head-Up Tilt Test in Patients With Unexplained Syncope: A Semi-Crossover Randomized Clinical Trial With Prospective Follow-Up, Journal of Interventional Cardiac Electrophysiology (2021)
62. Cost-Effectiveness Analysis of Mitral Valve Repair With the Mitraclip Delivery System for Patients With Mitral Regurgitation: A Systematic Review, Heart Failure Reviews (2021)
63. Cost-Effectiveness of Cardiac Resynchronization Therapy Plus an Implantable Cardioverter-Defibrillator in Patients With Heart Failure: A Systematic Review, Cost Effectiveness and Resource Allocation (2021)
64. Effect of Intermediate-Dose Vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With Covid-19 Admitted to the Intensive Care Unit: The Inspiration Randomized Clinical Trial, JAMA - Journal of the American Medical Association (2021)
65. Fluid Management in Acute Cardiac Condition and Superimposed Covid-19 Infection. Do We Need a Careful Revision?, Caspian Journal of Internal Medicine (2021)
66. Intermediate-Dose Versus Standard-Dose Prophylactic Anticoagulation in Patients With Covid-19 Admitted to the Intensive Care Unit: 90-Day Results From the Inspiration Randomized Trial, Thrombosis and Haemostasis (2021)
67. Mid-Term Outcomes of Off-Pump Versus On-Pump Coronary Artery Bypass Graft Surgery; Statistical Challenges in Comparison, BMC Cardiovascular Disorders (2021)
68. Predictive Inflammation-Related Micrornas for Cardiovascular Events Following Early-Onset Coronary Artery Disease, Archives of Medical Research (2021)
69. Prevalence and Trends of Coronary Artery Disease Risk Factors and Their Effect on Age of Diagnosis in Patients With Established Coronary Artery Disease: Tehran Heart Center (2005–2015), BMC Cardiovascular Disorders (2021)
70. Prognostic Impact of Prediabetes on Patient Outcomes After Coronary Artery Bypass Grafting: A Single-Center Cohort Study, Critical Pathways in Cardiology (2021)
71. Sex and Age Difference in Risk Factor Distribution, Trend, and Long-Term Outcome of Patients Undergoing Isolated Coronary Artery Bypass Graft Surgery, BMC Cardiovascular Disorders (2021)
72. Significance of Preoperative Left Ventricular Ejection Fraction in 5-Year Outcome After Isolated Cabg, Journal of Cardiothoracic Surgery (2021)
73. Tehran Cohort Study (Tecs) on Cardiovascular Diseases, Injury, and Mental Health: Design, Methods, and Recruitment Data, Global Epidemiology (2021)
74. The Syncope Unit of Tehran Heart Center, European Heart Journal (2021)
75. A Systematic Review of the Cost-Effectiveness of Heart Valve Replacement With a Mechanical Versus Biological Prosthesis in Patients With Heart Valvular Disease, Heart Failure Reviews (2020)
76. Can Respirator Face Masks in a Developing Country Reduce Exposure to Ambient Particulate Matter?, Journal of Exposure Science and Environmental Epidemiology (2020)
77. Comparison of Oral and Intravenous N-Acetyl Cysteine in Preventing Contrast Nephropathy, Indian Journal of Nephrology (2020)
78. Effect of Persistent Opium Consumption After Surgery on the Long-Term Outcomes of Surgical Revascularisation, European Journal of Preventive Cardiology (2020)
79. Intermediate Versus Standard-Dose Prophylactic Anticoagulation and Statin Therapy Versus Placebo in Critically-Ill Patients With Covid-19: Rationale and Design of the Inspiration/Inspiration-S Studies, Thrombosis Research (2020)
80. Left Atrial Size; a Missing Component in Scoring Systems for Predicting Atrial Fibrillation Following Coronary Artery Bypass Surgery, Acta Cardiologica Sinica (2020)
81. Opium and Cardiovascular Health: A Devil or an Angel?, Indian Heart Journal (2020)
82. Relationship Between the Severity of Coronary Artery Disease and Cardiovascular Risk Factors in Acute Coronary Syndrome: Based on Tehran Heart Center’S Data Registry, Journal of Tehran University Heart Center (2020)
83. Safety of Thrombolytic Therapy in Patients With Prosthetic Heart Valve Thrombosis Who Have High International Normalized Ratio Levels, Journal of Cardiac Surgery (2020)
84. Smoking Cessation After Surgery and Midterm Outcomes of Surgical Revascularization, Annals of Thoracic Surgery (2020)
85. The Association of Statins for Secondary Prevention With Progression to Diabetes in Patients With Prediabetic State After Coronary Artery Bypass Graft Surgery: A Retrospective Cohort Study, Journal of Diabetes and its Complications (2020)
86. The Impact of a Dedicated Coronavirus Disease 2019 Primary Angioplasty Protocol on Time Components Related to St-Segment Elevation Myocardial Infarction Management in a 24/7 Primary Percutaneous Coronary Intervention–Capable Hospital, Kardiologia Polska (2020)
87. The Need for Permanent Pacemaker After Restoration of Conduction Following Atrioventricular Block: A Retrospective Cohort Study; [Atriyoventrikuler Blogu Takiben Iletimin Restorasyonu Sonrasi Kalici Kalp Pili Gereksinmesi: Geriye Donuk Bir Kohort Calismasi], Turk Kardiyoloji Dernegi Arsivi (2020)
88. Twelve-Year History of Stemi Management in Tehran Heart Center: Concomitant Reduction of In-Hospital Mortality and Hospitalization Length, Archives of Iranian Medicine (2020)
89. Association Between Illness Perception and Health-Related Quality of Life in Patients With Preexisting Premature Coronary Artery Disease, Journal of Psychosomatic Research (2019)
90. Illness Perceptions in Patients With Premature Coronary Artery Disease: A Sex-Based Analysis 8 Years After the Diagnosis, Journal of Clinical Psychology in Medical Settings (2019)
91. Mid-Term Outcome and Prognosis of Prediabetic Patients After Coronary Artery Bypass Graft Surgery, Regardless of the First Month After Surgery, Critical Pathways in Cardiology (2019)
92. The Efficacy and Safety of Levetiracetam in the Prophylaxis of Migraine Headaches in Children - a Randomised Trial, Pediatria Polska (2019)
93. Are Prior Aspirin Users With St-Elevation Myocardial Infarction at Increased Risk of Adverse Events and Worse Angiographic Features?, Critical Pathways in Cardiology (2018)
94. Development of a Simple Risk Score Model to Predict Renal Artery Stenosis, Tehran University Medical Journal (2018)
95. Development of a Simple Risk Score Model to Predict Renal Artery Stenosis, Nephron (2018)
96. Non-Invasive Diagnosis of Early-Onset Coronary Artery Disease Based on Cell Type-Specific Gene Expression Analyses, Biomedicine and Pharmacotherapy (2018)
97. Non-Invasive Diagnosis of Early-Onset Coronary Artery Disease Based on Cell Type-Specific Gene Expression Analyses, Biomedicine and Pharmacotherapy (2018)
98. Novel Scoring System for Prediction of Cardiac Syndrome X: In Women With Typical Angina and a Positive Exercise Tolerance Test, Texas Heart Institute Journal (2018)
99. Application of Short Message Service to Control Blood Cholesterol: A Field Trial, BMC Medical Informatics and Decision Making (2017)
100. Effective Attenuation of Vascular Restenosis Following Local Delivery of Chitosan Decorated Sirolimus Liposomes, Carbohydrate Polymers (2017)
101. Effects of Injection-Site Splinting on the Incidence of Phlebitis in Patients Taking Peripherally Infused Amiodarone: A Randomized Clinical Trial, Journal of Vascular Nursing (2017)
102. Evaluation of Left Ventricular Longitudinal Deformation in Patients With and Without St Segment Depression During Supraventricular Tachycardia, Journal of Clinical Ultrasound (2017)
103. Impact of Sex on Long-Term Clinical Outcomes After Percutaneous Coronary Intervention, Critical Pathways in Cardiology (2017)
104. Physicochemical Characteristics of Liposomes Are Decisive for Their Antirestenosis Efficacy Following Local Delivery, Nanomedicine (2017)
105. Predictors of High-Sensitivity Cardiac Troponin T Elevation: In Patients With Acute Paroxysmal Supraventricular Tachycardia and Ischemic Heart Disease, Texas Heart Institute Journal (2017)
106. Preoperative Hemoglobin A1c and the Occurrence of Atrial Fibrillation Following On-Pump Coronary Artery Bypass Surgery in Type-2 Diabetic Patients, Critical Pathways in Cardiology (2017)
107. Sex-Dependent Effects of Diabetes Mellitus on the Revascularization Rate in Mid-Term Follow up of Young Patients With Coronary Artery Disease, Journal of Diabetes and its Complications (2017)
108. Analyzing Gensini Score As a Semi-Continuous Outcome, Journal of Tehran University Heart Center (2016)
109. Association Of-77T>C and Arg194trp Polymorphisms of Xrcc1 With Risk of Coronary Artery Diseases in Iranian Population, Iranian Journal of Basic Medical Sciences (2016)
110. Effect of Baseline Red Blood Cell Distribution Width on Short-And Intermediate-Term Mortality of Patients Under Primary Percutaneous Coronary Intervention a Survival Analysis, Critical Pathways in Cardiology (2016)
111. Factors Associated With Anxiety in Premature Coronary Artery Disease Patients: Thc-Pac Study, Acta Medica Iranica (2016)
112. Factors Associated With Depressive Symptoms in Young Adults With Coronary Artery Disease: Tehran Heart Center's Premature Coronary Atherosclerosis Cohort (Thc-Pac) Study, Iranian Journal of Psychiatry (2016)
113. Syncope Paradox in the Outcome of Patients With Pulmonary Thromboembolism: Short-Term and Midterm Outcome, Clinical Respiratory Journal (2016)
114. Assessment of Adherence to Acc/Aha Guidelines in Primary Management of Patients With Nstemi in a Referral Cardiology Hospital, Critical Pathways in Cardiology (2015)
115. Introducing the Tehran Heart Center's Premature Coronary Atherosclerosis Cohort: Thc-Pac Study, Journal of Tehran University Heart Center (2015)
116. Relationship Between Red Blood Cell Distribution Width and Mortality of Patients With Acute Myocardial Infarction Referring to Tehran Heart Center, Critical Pathways in Cardiology (2015)
117. The Role of Neutrophil-Gelatinase-Associated Lipocalin in Early Diagnosis of Contrast Nephropathy, Indian Journal of Nephrology (2015)