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Global, Regional, and National Burden of Migraine in 204 Countries and Territories, 1990 to 2019 Publisher Pubmed



Safiri S1, 2 ; Pourfathi H3 ; Eagan A4, 5 ; Mansournia MA6 ; Khodayari MT7 ; Sullman MJM8, 9 ; Kaufman J10 ; Collins G11, 12 ; Dai H13 ; Bragazzi NL13 ; Kolahi AA14
Authors
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Authors Affiliations
  1. 1. Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Anesthesiology and Pain Management, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Department of Global Health and Social Medicine, Harvard University, Boston, MA, United States
  5. 5. Department of Social Services, Tufts Medical Center, Boston, MA, United States
  6. 6. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Epidemiology and Biostatistics, School of Public Health, Maragheh University of Medical Sciences, Maragheh, Iran
  8. 8. Department of Social Sciences, University of Nicosia, Nicosia, Cyprus
  9. 9. Department of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus
  10. 10. Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, QC, Canada
  11. 11. Centre for Statistics in Medicine, NDORMS, Botnar Research Centre, University of Oxford, Oxford, United Kingdom
  12. 12. NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
  13. 13. Centre for Disease Modelling, York University, Toronto, ON, Canada
  14. 14. Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Pain Published:2022


Abstract

Data from the Global Burden of Disease Study 2019 were used to report the burden of migraine in 204 countries and territories during the period 1990 to 2019, through a systematic analysis of point prevalence, annual incidence, and years lived with disability (YLD). In 2019, the global age-standardised point prevalence and annual incidence rate of migraine were 14,107.3 (95% Uncertainty Interval [UI] 12,270.3-16,239) and 1142.5 (95% UI 995.9-1289.4) per 100,000, an increase of 1.7% (95% UI 0.7%-2.8%) and 2.1% (95% UI 1.1%-2.8%) since 1990, respectively. Moreover, the global age-standardised YLD rate in 2019 was 525.5 (95% UI 78.8-1194), an increase of 1.5% (95% UI -4.4% to 3.3%) since 1990. The global point prevalence of migraine in 2019 was higher in females and increased by age up to the 40 to 44 age group, then decreased with increased age. Belgium (22,400.6 [95% UI: 19,305.2-26,215.8]), Italy (20,337.7 [95% UI: 17,724.7-23,405.8]), and Germany (19,436.4 [95% UI: 16,806.2-22,810.3]) had the 3 highest age-standardised point prevalence rates for migraine in 2019. In conclusion, there were large intercountry differences in the burden of migraine, and this burden increased significantly across the measurement period. These findings suggest that migraine care needs to be included within the health system to increase population awareness regarding the probable risk factors and treatment strategies especially among young adults and middle-aged women, as well as to increase the data on migraines. © 2021 International Association for the Study of Pain
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